AZOREDUCTASE

作品数：7被引量：12H指数：2
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相关领域：环境科学与工程生物学更多>>
相关期刊：《Journal of Applied Mathematics and Physics》《Frontiers of Environmental Science & Engineering》《Journal of Environmental Sciences》《Chinese Journal of Natural Medicines》更多>>
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Application of a Pulsed Electric Field to Modify the Free Energy of the Active Site of an Azoreductase
《Journal of Applied Mathematics and Physics》2024年第1期249-255,共7页Jesus Magyber de Jesus Miranda Pedro Guillermo Reyes-Romero Jorge Mulia-Rodríguez Daniel Osorio-González 
The Gibbs free energy is strongly related to the stability and catalytic function of an enzyme through the energetic changes that occur in the chemical reactions the enzyme catalyzes. In this in silico study, a pulsed...
关键词：Pulsed Electric Field Molecular Dynamics DOCKING AZOREDUCTASE 
A near-infrared multifunctional fluorescent probe for hypoxia monitoring and tumor-targeted therapy被引量：2
《Chinese Chemical Letters》2022年第3期1589-1594,共6页Yuxun Lu Jiajia Xu Zongyun Jia Siyu Kong Yimu Qiao Lin Li Qiong Wu Ying Zhou 
supported by the National Natural Science Foundation of China (No. 22067019);China-Sweden Joint Mobility Project(No. 51811530018);the Scientific Researchof Yunnan Provincial Department of Education (No. 2021Y031)。
Hypoxia is one of the key characteristics of solid tumors. The over-expression of azoreductase resulting from hypoxia can be used as a target to visualize hypoxic levels and a trigger of the drug release system in tum...
关键词：AZOREDUCTASE HYPOXIA THERANOSTIC Tumor 
Identification of a new azoreductase driven prodrug from bardoxolone methyl and 5-aminosalicylate for the treatment of colitis in mice
《Chinese Journal of Natural Medicines》2021年第7期545-550,共6页QIAO Xin GONG Yan MOU Yi ZHANG Yi-Hua HUANG Zhang-Jian WEN Xiao-Dong 
supported by the National Natural Science Foundation of China(Nos.81773573 and 21977116);the Natural Science Fund for Colleges and Universities in Jiangsu Province(No.17KJB350011);the Open Project of State Key Laboratory of Natural Medicines(No.SKLNMZZCX201824);the State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia(No.SKL-HIDCA-2018-1).
For local treatment of ulcerative colitis,a new azoreductase driven prodrug CDDO-AZO from bardoxolone methyl(CDDO-Me)and 5-aminosalicylate(5-ASA)was designed,synthesized and biologically evaluated.It is proposed that ...
关键词：Ulcerative colitis AZOREDUCTASE PRODRUG Bardoxolone Methyl 5-Aminosalicylate 
Application of 2D fluorescence correlation method to investigate the dilution-induced heterogeneous distribution of the bound FMN in azoreductase
《Chinese Chemical Letters》2015年第2期210-214,共5页Juan Feng Ting Han Mi-Qing Zhang Yu Zhou Qing-Qin Wu 
fund by sub-project of National Science and Technology Major Project on Water Pollution Prevention and Control(No.2012ZX07203-003-Z04);supported by the Fundamental Research Funds for the Central Universities(No. ZYGX2012J112)
AzoR is a homodimeric,flavin mononucleotide（FMN）-containing,NADH-dependent azoreductase from Escherichia coli.In this paper,we investigated the effect of the concentration of both AzoR and R59 G on the spectral beha...
关键词：Azoreductase FMN 2D fluorescence correlation spectra Heterogeneous distribution 
Decolorization of azo dyes by a salt-tolerant Staphylococcus cohnii strain isolated from textile wastewater被引量：2
《Frontiers of Environmental Science & Engineering》2012年第6期806-814,共9页Bin YAN Cuihong DU Meilan XU Wenchao LIAO 
The salt-tolerant Staphylococcus cohnii strain, isolated from textile wastewater, has been found effective on decolorizing several kinds of azo dyes with different structures. The optimal conditions for azo dye acid r...
关键词：Staphylococcus cohnii DECOLORIZATION salt azoreductase Nicotineamide adenine dinucleotide-dichlor-ophenol indophenol （NADH-DCIP） reductase 
Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases被引量：4
《Protein & Cell》2010年第8期780-790,共11页Ali Ryan Chan-Ju Wang Nicola Laurieri Isaac Westwood Edith Sim 
Azoreductases are involved in the bioremediation by bacteria of azo dyes found in waste water.In the gut flora,they activate azo pro-drugs,which are used for treatment of inflammatory bowel disease,releasing the activ...
关键词：AZOREDUCTASE enzyme mechanism NAD(P)H quinone oxidoreductase enzyme characterisation convergent evolution 
Biodegradation of azo dyes by genetically engineered azoreductase被引量：4
《Journal of Environmental Sciences》2005年第4期545-550,共6页WANGJing YANBin ZHOUJi-ti BAOYong-ming LUHong YUANXiao-dong 
TheFoundationoftheCross centuryTalentofMinistryofEducationChina
A azoreductase gene with 537 bp was obtained by PCR amplification from Rhodobacter sphaeroides AS1 1737 The enzyme, with a molecular weight of 18 7 kD, was efficiently expressed in Escherichia coli and its biodegr...
关键词：genetically engineered microorganisms AZOREDUCTASE BIODEGRADATION azo dyes 
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