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Exploring the significance of extracellular vesicles:Key players in advancing cancer and possible theranostic tools: 《Cancer Pathogenesis and Therapy》2025年第2期109-119,共11页Bhaumik Patel Shreyas Gaikwad Sahdeo Prasad; Metastasis remains a critical challenge in cancer treatment and the leading cause of cancer-related mortality.Ongoing research has demonstrated the key role of extracellular vesicles(EVs)in facilitating communication ...; 关键词：Extracellular vesicle(EV) Cancer metastasis BIOMARKER Bioengineered EV

Photothermal lanthanide nanomaterials: From fundamentals to theranostic applications: 《BMEMat(BioMedical Engineering Materials)》2024年第4期1-17,共17页Zhuo Li Jiacheng Gong Shan Lu Xingjun Li Xiaobo Gu Jin Xu Jawairia Umar Khan Dayong Jin Xueyuan Chen; National Key Research and Development Program of China,Grant/Award Number:2022YFB3503700;National Natural Science Foundation of China,Grant/Award Numbers:12174392,22175179,22135008,U22A20398;Natural Science Foundation of Fujian Province,Grant/Award Numbers:2021I0040,2022I0035,2021L3024,2021J01524;Self-deployment Project Research Program of Haixi Institutes,Chinese Academy of Sciences,Grant/Award Numbers:CXZX-2022-GH10,CXZX-2022-GS01。; Photothermal lanthanide nanomaterials with unique photophysical properties have been innovatively explored for diagnostics and non‐invasive therapies,and hold great promise for precision theranostics.In this review,w...; 关键词：lanthanide nanomaterials optical imaging photothermal mechanism photothermal therapy temperature feedback THERANOSTICS

An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy:Real-time tumor-tracking and chemical-enhanced photodynamic therapy: 《Chinese Chemical Letters》2024年第12期254-259,共6页Jia-Qi Feng Xiang Tian Rui-Ge Cao Yong-Xiu Li Wen-Long Liu Rong Huang Si-Yong Qin Ai-Qing Zhang Yin-Jia Cheng; financially supported by Natural Science Foundation of China(Nos.52173295,52273313,22377152,52202357);the Fundamental Research Funds for the Central Universities,South-Central Minzu University(Nos.CZQ23036,CZY22005);the Knowledge Innovation Program of Wuhan-Basic Research(No.2023020201010150)。; The combination of diagnostic and therapeutic agents in the form of theranostic platforms to enhance tumor therapeutic efficacy is receiving increasing attention in recent years.However,simultaneous encapsulation,embe...; 关键词：Photodynamic-chemotherapy Co-assembly AIE photosensitizer Peptide drug THERANOSTICS

Recent biological applications of corroles:From diagnosis to therapy: 《无机化学学报》2024年第12期2303-2317,共15页XU Jialiang CUI Jiabin; 国家自然科学基金青年项目(No.22104105);江苏省自然科学基金青年项目(No.bk20210702);姑苏创新创业青年领军人才项目(No.zxl2022515)资助。; Corrole,a representative branch of porphyrin,has recently gained popularity.These molecules,viewed as ring‑contracted porphyrinoids containing direct pyrrole‑pyrrole linkages due to the absence of a meso‑carbon atom,e...; 关键词：CORROLE metallocorrole photodynamic therapy in vivo imaging THERANOSTIC

3D-printed aerogels as theranostic implants monitored by fluorescence bioimaging: 《Bioactive Materials》2024年第11期471-484,共14页Ana Iglesias-Mejuto Rui Pinto Pedro Faísca JoséCatarino João Rocha Luisa Durães Maria Manuela Gaspar Catarina Pinto Reis Carlos A.García-González; MICIU/AEI/10.13039/501100011033[Grants PID2020-120010RB-I00 and PDC2022-133526-I00];ERDF/EU and European Union NextGenerationEU/PRTR,Fundação para a Ciência e Tecnologia(FCT),doi:10.54499/UIDB/00645/2020,doi:10.54499/UIDP/00645/2020,UIDB/04138/2020,UIDP/04138/2020,doi:10.54499/UIDB/00102/2020 and doi:10.54499/UIDP/00102/2020;The work was carried out in the framework of the COST Innovators Grant IG18125“Technical,commercial and societal innovations on aerogels towards circular economy”(ECO-AERoGELS)funded by the European Commission.A.I.-M.; Aerogel scaffolds are nanostructured materials with beneficial properties for tissue engineering applications.The tracing of the state of the aerogels after their implantation is challenging due to their variable biod...; 关键词：Upconversion nanoparticles AEROGELS Theranostic implants In vivo fluorescence

Photoluminescence and photothermal conversion in boric acid derived carbon dots for targeted microbial theranostics: 《Chinese Chemical Letters》2024年第9期232-237,共6页Yiqiao Chen Ao Liu Biwen Yang Zhenzhen Li Binggang Ye Zhouyi Guo Zhiming Liu Haolin Chen; supported by the National Natural Science Foundation of China(Nos.32071399 and 62175071);the Guangdong Basic and Applied Basic Research Foundation(Nos.2021A1515011988 and 2021A1515110265);the Science and Technology Program of Guangzhou(No.2019050001);the Project on the Education Department of Guangdong(Nos.2021KTSCX238 and 2022ZDZX2077);the Natural Science Research Project of Guangdong Food and Drug Vocational College(Nos.2020ZR01 and 2022ZR02).; Theranostic carbon dots(CDs)have attracted widespread attention recently due to their tunable optical properties and diverse bioactivities.Beyond fluorescent imaging application,the photothermal property endows CDs wi...; 关键词：Theranostic carbon dots Fluorescence imaging Phenylboronic acid Photothermal therapy Nanotheranostic

pH-Responsive Theranostic Colloidosome Drug Carriers Enable Real-Time Imaging of Targeted Thrombolytic Process with Near-Infrared-II for Deep Venous Thrombosis: 《Research》2024年第3期17-33,共17页Yaxin Ye Zhechang Chen Shengzhang Zhang Paul Slezak Fei Lu Ruiqi Xie Dongwon Lee Guangqian Lan Enling Hu; the National Natural Science Foundation of China(No.52103096);the Natural Science Foundation of Chongqing,China(cstb2022nscq-msx0555);the Fundamental Research Funds for Central Universities(No.SWU-XDPY22010).; Thrombosis can cause life-threatening disorders. Unfortunately, current therapeutic methods for thrombosis using injecting thrombolytic medicines systemically resulted in unexpected bleeding complications. Moreover, t...; 关键词：INFRARED enable eliminated

Development and Characterization of Novel FAP-Targeted Theranostic Pairs: A Bench-to-Bedside Study: 《Research》2024年第3期473-485,共13页Wei Huang Yizhen Pang Qiufang Liu Chenyi Liang Shuxian An Qianyun Wu You Zhang Gang Huang Haojun Chen Jianjun Liu Weijun Wei; the National Key Research and Development Program of China(Grant No.2020YFA0909000);the National Natural Science Foundation of China(Grant Nos.82372014,82001878,and 82071961);the Shen Kang-United Imaging Joint Research and Development Plan(Grant No.SKLY2022CRT301).; Fibroblast activation protein (FAP) is among the most popular targets in nuclear medicine imaging and cancer theranostics. Several small-molecule moieties (FAPI-04, FAPI-46, etc.) are used for developing FAP-targeted ...; 关键词：DOTA EXPRESSING labeled

pH-responsive metal nanoparticles as high contrast theranostic agents for selective imaging and synergistic cancer therapy: 《Science China Chemistry》2024年第9期3063-3070,共8页Sichao Tian Xiaofeng He Xiao Wu Dongxue Hu Qing-Hua Xu; supported by the Science and Technology Project of Jiangsu Province(BZ2022056);the Ministry of Education,Singapore(Tier 1 A-8000013-00-00)。; The low signal-to-noise ratio(S/N)and single functionality of fluorescence imaging agents have limited their practical applications.Bright two-photon excitation(2PE)imaging probes are highly desirable in vivo with lar...; 关键词：metal nanoparticles two-photon excitation high contrast imaging agents fluorescence imaging cancer therapy

Active molecule-based theranostic agents for tumor vasculature normalization and antitumor efficacy: 《Chinese Chemical Letters》2024年第8期229-234,共6页Jin Wang Xiaoyan Pan Junyu Zhang Qingqing Zhang Yanchen Li Weiwei Guo Jie Zhang; supported by the National Natural Science Foundation of China(NSFC,Nos.82373793,82173742);the Science Fund for Distinguished Young Scholars of Shaanxi Province(No.2022JC-54);the Key Research and Development Program of Shaanxi Province(No.2023-YBSF-131).; Tumor vascular normalization has emerged as a promising strategy for synergistic therapy recently.Based on the strategy of“fluorescence turn on-controllable release”,a novel bifunctional candidate was con-structed b...; 关键词：Tumor vasculature normalization Diagnosis and treatment CYTOTOXICITY Depleting glutathione Ferroptosis Immune activation

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