HONOKIOL

作品数：41被引量：175H指数：9
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相关领域：医药卫生更多>>
相关作者：白小红王晓园全红陈璇曾燕如更多>>
相关机构：重庆医科大学河南科技大学山西医科大学浙江林学院更多>>
相关期刊：《Chinese Herbal Medicines》《Journal of Animal Science and Biotechnology》《Green Energy & Environment》《Chinese Journal of Integrative Medicine》更多>>
相关基金：国家自然科学基金泰国研究基金山西省自然科学基金重庆市渝中区科技计划项目更多>>
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Honokiol Prevents Intestinal Barrier Dysfunction in Mice with Severe Acute Pancreatitis and Inhibits JAK/STAT1 Pathway and Acetylation of HMGB1被引量：1
《Chinese Journal of Integrative Medicine》2024年第6期534-542,共9页LI Jie CHEN Ya-feng GAO Lei LI Yi-jie FENG Dian-xu 
Supported by National Natural Science Foundation of China(No.81803920 and 81673789);Key Medical Specialty Construction Project of Shanghai Municipal Health Commission(No.ZK2019B18);Shanghai Putuo District Health Commission Characteristic Disease Construction Project(No.2020TSZB03)。
Objective To investigate the effect of honokiol(HON)and the role of high-mobility group protein B1(HMGB1)on the pathogenesis of severe acute pancreatitis(SAP).Methods Thirty mice were numbered according to weight,and ...
关键词：severe acute pancreatitis intestinal barrier dysfunction HONOKIOL high-mobility group protein B1 Januskinase signal transducerand activatorof transcription1 
Revealing the role of honokiol in human glioma cells by RNA-seq analysis
《BIOCELL》2024年第6期945-958,共14页YUNBAO GUO XU LIU QI XU XIAOTONG ZHOU JIAWEI LIU YANYAN XU YAN LU HAIYAN LIU 
The study was supported by the Natural Science Foundation of Jilin Province(Grant No.20200201444JC).
Background:Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve tissue.Honokiol is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark ...
关键词：Human glioma HONOKIOL RNA-SEQ APOPTOSIS Ferroptosis MAPK 
Comprehensive reutilization of herbal waste:Coproduction of magnolol,honokiol,and β-amyrin from Magnolia officinalis residue被引量：1
《Green Energy & Environment》2024年第2期403-412,共10页Lukun Xiao Anyi Zhao Jie Qiu An Liu Sha Chen Jinzhu Jiang Jun Zhang Cong Guo Jipeng Di Jintang Cheng Chang Chen Kangxin Hou Aiping Zhang Yan Liu Caixia Wang 
supported by the National Key Research and Development Project(2019YFC1906601);China the Scientific and Technological Innovation Project of the Chinese Academy of Chinese Medical Sciences(C12021A04111);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ13-YQ-040).
Herbal extraction residues(HERs)cause serious environmental pollution and resource waste.In this study,a novel green route was designed for the comprehensive reutilization of all components in HERs,taking Magnolia off...
关键词：Magnolia officinalis residues(MOR) Comprehensive utilization Metal-organic frame material BIOSYNTHESIS 
Effect of honokiol regulating SIRT3 on chronic hypoxia-induced microglia and astrocyte polarization
《Journal of Hainan Medical University》2024年第2期1-6,共6页ZHANG Miao GAO Xing-hong HU Yuan 
National Natural Science Foundation of China(No.82101280)。
Objective:To investigate the effect of honokiol on microglia polarization and the underlying mechanism.Methods:Inflammatory factors were detected using ELISA to determine the optimal concentration of cobalt chloride t...
关键词：Honokiol Astrocyte POLARIZATION Sirutin3 
Compound from Magnolia officinalis Ameliorates White Matter Injury by Promoting Oligodendrocyte Maturation in Chronic Cerebral Ischemia Models被引量：1
《Neuroscience Bulletin》2023年第10期1497-1511,共15页Zhi Zhang Xin Shu Qian Cao Lushan Xu Zibu Wang Chenggang Li Shengnan Xia Pengfei Shao Xinyu Bao Liang Sun Yuhao Xu Yun Xu 
This work was supported by the National Natural Science Foundation of China(81920108017 and 82130036);the Key Research and Development Program of Jiangsu Province of China(BE2020620);the Jiangsu Province Key Medical Discipline(ZDXKA2016020).
Chronic cerebral hypoperfusion leads to white matter injury(WMI),which subsequently causes neurodegeneration and even cognitive impairment.However,due to the lack of treatment specifically for WMI,novel recognized and...
关键词：HONOKIOL White matter injury OLIGODENDROCYTE Vascular dementia 
Honokiol attenuates acetaminophen-induced acute liver injury by inhibiting hepatic CYP1A2 activity and improving liver mitochondrial dysfunction被引量：3
《Chinese Herbal Medicines》2023年第2期231-239,共9页Xiaolei Miao Chengting Jin Jiao Liu Junjun Wang Yong Chen 
supported by the Department of Education of Hubei Province,China(No.Q20181004).
Objective:Acetaminophen(APAP)overdose is a common cause of liver injury.This study aimed to investigate the protective effect of honokiol(Hon)against APAP-induced hepatotoxicity and its potential mechanism.Methods:C57...
关键词：ACETAMINOPHEN CYP1A2 HONOKIOL liver mitochondrial dysfunction Magnolia officinalis Rehd.et Wils. oxidant stress 
Honokiol attenuates mitochondrial fission and cell apoptosis by activating Sirt3 in intracerebral hemorrhage被引量：2
《Chinese Medical Journal》2023年第6期719-731,共13页Xuecheng Zheng Junling Gao Manman Zhao Lingling Han Dexin Zhang Kaijie Wang Jianzhong Cui 
Natural Science Foundation of Hebei Province(No.H2019105137)
Background:Sirtuin-3(Sirt3)has been documented to protect against mitochondrial dysfunction and apoptosis.Honokiol(HKL)is a Sirt3 pharmacological activator with reported neuroprotective effects in multiple neurologica...
关键词：APOPTOSIS Drp1 HONOKIOL Intracerebral hemorrhage Mitochondrial fission Sirt3 
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis被引量：2
《Acta Pharmaceutica Sinica B》2023年第2期577-597,共21页Yujun Zhou Jingshu Tang Jiaqi Lan Yong Zhang Hongyue Wang Qiuyu Chen Yuying Kang Yang Sun Xinhong Feng Lei Wu Hongtao Jin Shizhong Chen Ying Peng 
supported by the grants from National Natural Science Foundation of China(Nos.82073835 and 81872855);National Key R&D Program of China(No.2019YFC1708901);CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1028);Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study(BZ0150,China);Disciplines construction project(201920200802,China)。
Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease affecting both upper and lower motor neurons(MNs)with large unmet medical needs.Multiple pathological mechanisms are considered to contribut...
关键词：Amyotrophic lateral sclerosis GLUTATHIONE HONOKIOL Mitochondrial biogenesis Mitochondrial dynamics NRF2 Oxidative stress SOD1-G93A 
Liposomal Honokiol induces ROS-mediated apoptosis via regulation of ERK/p38-MAPK signaling and autophagic inhibition in human medulloblastoma被引量：4
《Signal Transduction and Targeted Therapy》2022年第3期625-627,共3页Shenglan Li Jinyi Chen Yaqiong Fan Ce Wang Can Wang Xiaohong Zheng Feng Chen Wenbin Li 
This study was funded by the National Natural Science Foundation of China(No.81972338);Clinical Major Specialty Projects of Beijing(2-1-2-038).
Dear Editor,Nowadays,medulloblastoma accounts for approximately 25% of all pediatric brain tumors.1 Even with the successful treatment of primary tumors,there are still serious side effects.Honokiol(HNK)is defined as ...
关键词：TUMORS pediatric LIPO 
Supplemental magnolol or honokiol attenuates adverse effects in broilers infected with Salmonella pullorum by modulating mucosal gene expression and the gut microbiota被引量：13
《Journal of Animal Science and Biotechnology》2022年第1期288-302,共15页Fang Chen Hao Zhang Encun Du Qiwen Fan Na Zhao Feng Jin Wei Zhang Wanzheng Guo Shaowen Huang Jintao Wei 
supported by the project of Hubei innovation center of agricultural science and technology(grant number 2016-620-000-001-028);National Natural Science Foundation of China(31702309);the Youth Fund of Hubei Academy of Agricultural Sciences(2019NKYJJ03).
Background:Salmonella pullorum is one of the most harmful pathogens to avian species.Magnolol and honokiol,natural compounds extracted from Magnolia officinalis,exerts anti-inflammatory,anti-oxidant and antibacterial ...
关键词：BROILER Gut microbiota HONOKIOL Immune MAGNOLOL Salmonella pullorum 
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