financially supported by the National Key Research and Development Program of China(No.2019YFA0705803);the National Natural Science Foundation of China Youth Fund(Nos.51803174,82102470);the Natural Science Foundation of Sichuan Province(No.24NSFSC4798);the Foundation of Sichuan Engineering Technology Research Center of Basalt Fiber Composites Development and Application of Southwest Petroleum University(No.2022SCXWYXWFC002);the support from the School of New Energy and Materials of Southwest Petroleum University;Sichuan International Science and Technology Cooperation Base;Dalian Institute of Chemical Physics of Chinese Academy of Sciences。
Fe-based Fenton agents can generate highly reactive and toxic hydroxyl radicals(·OH)in the tumor microenvironment(TME)for chemodynamic therapy(CDT)with high specificity.However,the low pH environment and insufficient...
supported by grants from the Natural Science Foundation of Anhui Province(grant number 2208085MH253);the National Natural Science Foundation(grant number 81702560);the Fundamental Research Funds for the Central Universities(grant number WK9110000110),People's Republic of China.
Lactobacillus crispatus is a commonly found species in the urogenital tract(UGT)of healthy females and can also colonize other niches,such as the gastrointestinal tract(GIT).Although its potential protective role in c...
Natural Science Foundation of Hubei Province,Grant/Award Number:2019CFB606;National Natural Science Foundation of China,Grant/Award Number:52072139;Innovation Platform for Academicians of Hainan Province。
Destruction of cellular redox homeostasis to induce cancer cell apoptosis is an emerging tumor therapeutic strategy. To achieve this goal, elevating exogenous oxidative stress or impairing the antioxidant defense syst...
supported by the National Natural Science Foundation of China(32001481);the Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences;the China Agriculture Research System,the National Modern Agricultural Industry Technology System of China(CARS-18–05);the Provincial Key R&D and Promotion Special Projects in Henan(232102110178);the Program for Key Areas of Science and Technology of Xinjiang Production and Construction Corps Third Division and Tumsuk City(KY2021GG08);the Central Public-interest Scientific Institution Basal Research Fund(1610162023019)。
Background Ensuring that seeds germinate and emerge normally is a prerequisite for cotton production,esp.in areas with salinized soil.Priming with mepiquat chloride(MC)can promote seed germination and root growth unde...
supported by National Natural Science Foundation of China(No.21763028);Science and Technology project of Shaanxi Province(Nos.2022NY-071,2022QFY07-05,2022JZ-49)。
With the rapid development of economy, industrial and agricultural pollutants have caused great damage to the ecological environment and the normal development of organisms, posing a serious threat to global public he...
The results presented in"The anthocyanin biosynthetic regulator MdMYBl positively regulates ascorbic acid biosynthesis in apple"(An et al.#this issue)provide evidence for a new mechanism for the elevation of ascorbate...
Pancreatic ductal adenocarcinoma(PDAC)is a lethal disease with limited therapeutic options.Despite extensive clinical research over the past several decades,meaningful improvements in care standards have been challeng...
BACKGROUND The effectiveness of colonoscopy strictly depends on adequate bowel cleansing.Recently,a 1 L polyethylene glycol plus ascorbate(PEG-ASC)solution(Plenvu;Norgine,Harefield,United Kingdom)has been introduced o...
supported by grants from the National Key Research&Development Plan(2018YFD1000800,2016YFD0100204-21);National Natural Science Foundation of China(31991182,31972426,and 31672166);Fundamental Research Funds for the Central Universities(2662018PY073);Wuhan Frontier Projects for Applied Foundation(2019020701011492).
Ascorbic acid(AsA),an important antioxidant and growth regulator,and it is essential for plant development and human health.Specifically,humans have to acquire AsA from dietary sources due to their inability to synthe...
National Science Foundation of China(21272018,90813032);Beijing Municipal Natural Science Foundation(7112144).
Importance: Clinical observations have implied a central origin for tinnitus and potential therapeutic effects of ascorbic acid (AA);however, the detailed mechanisms remain undetermined. Objective: To investigate chan...