TORPOR

作品数：14被引量：8H指数：1
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相关领域：生物学更多>>
相关机构：中国医学科学院更多>>
相关期刊：《World Journal of Gastroenterology》《Journal of Clinical & Translational Research》《Neural Regeneration Research》《Bulletin of the Chinese Academy of Sciences》更多>>
相关基金：国家自然科学基金国家科技重大专项更多>>
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Pathogenic strategies of Pseudogymnoascus destructans during torpor and arousal of hibernating
《四川生理科学杂志》2024年第7期1641-1641,共1页Marcos Isidoro-Ayza 
Millions of hibernating bats across North America have died from white-nose syndrome(WNS),an emerging disease caused by a psychrophilic(cold-loving)fungus,Pseudogymnoascus destructans,that invades their skin.Mechanism...
关键词：INVASION NAT FUNGUS 
The future of artificial hibernation medicine:protection of nerves and organs after spinal cord injury被引量：1
《Neural Regeneration Research》2024年第1期22-28,共7页Caiyun Liu Haixin Yu Zhengchao Li Shulian Chen Xiaoyin Li Xuyi Chen Bo Chen 
supported by the Key Projects of the National Natural Science Foundation of China,No.11932013(to XC);Key Military Logistics Research Projects,No.B WJ21J002(to XC);the Key projects of the Special Zone for National Defence Innovation,No.21-163-12-ZT006002-13(to XC);the National Nature Science Foundation of China No.82272255(to XC);the National Defense Science and Technology Outstanding Youth Science Fund Program,No.2021-JCIQ-ZQ-035(to XC);the Scientific Research Innovation Team Project of Armed Police Characteristic Medical Center,No.KYCXTD0104(to ZL);the National Natural Science Foundation of China Youth Fund,No.82004467(to BC)。
Spinal cord injury is a serious disease of the central nervous system involving irreversible nerve injury and various organ system injuries.At present,no effective clinical treatment exists.As one of the artificial hi...
关键词：artificial hibernation central thermostatic-resista nt regulation hypothermia multi-system protection neuroprotection organ protection spinal cord injury synthetic torpor 
Successful Hypothermia in Nonhuman Primate Paves the Way for Future Application in Human Torpor
《Bulletin of the Chinese Academy of Sciences》2022年第4期245-246,共2页ZHANG Xiaomin 
Hibernation is a state adopted by certain mammals as an adaptation to adverse winter conditions.Typical features of hibernation include greatly reduced metabolic activity and lowered body temperature.As warm-blooded a...
关键词：temperature. artificial HIBERNATE 
Torpor发生机制最新研究进展被引量：1
《药学学报》2021年第6期1532-1536,共5页朱子玉 姜剑伟 张建军 
国家自然科学基金:资助项目(81773715,81630094);国家科技重大新药创制专项项目(2018ZX09711001-001-012)。
Torpor是指在食物供应减少时期,为维持生存,动物体内代谢活性大幅降低的一种状态,表现为体温、代谢水平和运动水平大幅降低。哺乳动物拥有一套严格的体温调节系统以维持体温恒定,当能量长时间供给不足时,部分哺乳动物会进入冬眠状态,tor...
关键词：TORPOR adcyap神经元 瘦素 QRFP神经元 交感神经系统 
Continuous growth through winter correlates with increased resting metabolic rate but does not affect daily energy budgets due to torpor use
《Current Zoology》2021年第2期131-145,共15页Jan S.BORATYNSKI Karolina IWINSKA Paulina A.SZAFRANSKA Piotr CHIBOWSKI Wiestaw BOGDANOWICZ 
J.S.B.was supported by a grant from Polish National Science Center on the basis of decision number 2019/35/D/NZ8/03626.
Small mammals that are specialists in homeothermic thermoregulation reduce their self-maintenance costs of normothermy to survive the winter.By contrast,heterothermic ones that are considered generalists in thermoregu...
关键词：growth rate HETEROTHERMY phenotypic fexibiliy resting metabolic rate TORPOR 
Responding to the weather:energy budgeting by a small mammal in the wild
《Current Zoology》2020年第1期15-20,共6页Taylor HUME Fritz GEISER Shannon E.CURRIE Gerhard KORTNER Clare STAWSKI 
This research was supported by Honours research funds from the University of New England to T.H.,the University of New England Deputy Vice-Chancellor(Research)Award to C.S.and the Australian Research Council to F.G.
Energy conservation is paramount for small mammals because of their small size,large surface area to volume ratio,and the resultant high heat loss to the environment.To survive on limited food resources and to fuel th...
关键词：antechinus HETEROTHERMY MARSUPIAL semelparous TEMPERATURE TORPOR 
On the immunological limitations of hibernation and synthetic torpor as a supporting technique for astronauts’ radioprotection in deep space missions被引量：1
《World Journal of Immunology》2019年第1期1-4,共4页Joseph J Bevelacqua James Welsh Seyed Mohammad Javad Mortazavi 
Although human hibernation has been introduced as an effective technique in space exploration,there are concerns regarding the intrinsic risks of the approach(i.e.,synthetic torpor)and other factors involved in this p...
关键词：Space radiation HIBERNATION RADIOPROTECTION Synthetic torpor Immunology 
Potential role of the gut microbiota in synthetic torpor and therapeutic hypothermia被引量：1
《World Journal of Gastroenterology》2017年第3期406-413,共8页Claudia Sisa Silvia Turroni Roberto Amici Patrizia Brigidi Marco Candela Matteo Cerri 
Therapeutic hypothermia is today used in several clinical settings, among them the gut related diseases that are influenced by ischemia/reperfusion injury. This perspective paved the way to the study of hibernation ph...
关键词：Therapeutic HYPOTHERMIA GUT MICROBIOTA HIBERNATION DYSBIOSIS Synthetictorpor 
Primate Torpor: Regulation of Stress-activated Protein Kinases During Daily Torpor in the Gray Mouse Lemur, Microcebus murinus被引量：1
《Genomics, Proteomics & Bioinformatics》2015年第2期81-90,共10页Kyle K.Biggar Cheng-Wei Wu Shannon N.Tessier Jing Zhang Fabien Pifferi Martine Perret Kenneth B.Storey 
supported by a Discovery grant from the Natural Sciences and Engineering Research Council (NSERC) of Canada (Grant No. 6793);a grant from the Heart and Stroke Foundation of Canada (Grant No. G-140005874) to KBS. KBS holds the Canada Research Chair in Molecular Physiology;KKB, CWW, and SNT all held NSERC postgraduate scholarships
Very few selected species of primates are known to be capable of entering torpor. This exciting discovery means that the ability to enter a natural state of dormancy is an ancestral trait among primates and, in phylog...
关键词：Metabolic rate depression Signal transduction Mitogen activated protein kinase 
Regulation of the PI3K/AKT Pathway and Fuel Utilization During Primate Torpor in the Gray Mouse Lemur, Microcebus murinus
《Genomics, Proteomics & Bioinformatics》2015年第2期91-102,共12页Shannon N.Tessier Jing Zhang Kyle K.Biggar Cheng-Wei Wu Fabien Pifferi Martine Perret Kenneth B.Storey 
supported by a Discovery grant from the Natural Sciences and Engineering Research Council (NSERC) of Canada (Grant No. 6793);a grant from the Heart and Stroke Foundation of Canada (Grant No. G-14-0005874) to KBS. KBS holds the Canada Research Chair in Molecular Physiology;SNT, KKB, and CWW all held NSERC postgraduate scholarships
Gray mouse lemurs（Microcebus murinus） from Madagascar present an excellent model for studies of torpor regulation in a primate species. In the present study, we analyzed the response of the insulin signaling pathway...
关键词：Insulin signaling pathway PI3K/AKT m TOR GSK3 Pyruvate dehydrogenase Metabolic rate depression 
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