Introduction: The use of radioactive radiations in healthcare facilities must comply with radioprotection safety rules in order to avoid threatening the health of workers and patients. This study aimed to assess the w...
sponsored by the National Natural Science Foundation of China(82303681 and 82202950);Fundamental Research Funds for the Central Universities(3332022063);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-1-042);The National Natural Science Foundation of China(82202950);the Fundamental Research Funds for the Central Universities(3332022063);Feifei Xu,who participated in the research design.The National Natural Science Foundation of China(82303681);Wenfeng Gou,who participated in the research design;The Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-1-042);Wenbin Hou,who designed and conceived the study.
Objective:Camellia nitidissima Chi,a Chinese medicine commonly used by ethnic minorities in Guangxi,China,is beneficial for clearing heat,detoxifying,inducing diuresis,and suppressing swelling.It has various pharmacol...
supported by the Natural Science Foundation of Hunan Province(2021JJ30592);Health Commission Scientific Research Project of Hunan Province(D202309037942);Key Research Project of Education Department of Hunan Province(19A429);National Natural Science Foundation of China(81272994).
Background:Radiotherapy,a primary approach in cancer treatment,damages normal cells while targeting cancer cells.Therefore,it is crucial to identify drugs with minimal side effects,high reliability,and radioprotective...
supported by National Natural Science Foundation of China(82370929);Sichuan Science and Technology Program(2022NSFSC0002 and 2024NSFSC3508);Sichuan Province Youth Science and Technology Innovation Team(2022JDTD0021);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD03202302,RCDWJS2024-1);China Postdoctoral Science Foundation(GZB2023470);Sichuan Province Innovative Talent Funding Project for Postdoctoral Fellows(BX202317);The authors would like to thank Dr.Chenghui Li(Analytical&Testing Center,Sichuan University)for technical assistance in assisting with the particle size analysis.
Unnecessary exposure to ionizing radiation(IR)often causes acute and chronic oxidative damages to normal cells and organs,leading to serious physiological and even life-threatening consequences.Amifostine(AMF)is a val...
supported by the National Science Fund for Distinguished Young Scholars (82225025);National Natural Science Foundation of China (21877049,32171296,32101044);Guangdong Natural Science Foundation (2020B1515120043);K.C.Wong Education Foundation and China Postdoctoral Science Foundation (2022M711341).
Radiation-induced heart disease(RIHD),characterized by severe oxidative stress and immune dysregulation,is a serious condition affecting cancer patients undergoing thoracic radiation.Unfortunately,clinical interventio...
the National Natural Science Foundation of China(Nos.22175182,21471103);Sheng Yuan Cooperation(No.2021SYHZ0048);Beijing Natural Science Foundation(No.2202064);the directional institutionalized scientific research platform relies on Beijing Synchrotron Radiation Facility of Chinese Academy of Sciences.
Radiation damage can cause a series of gastrointestinal(GI)tract diseases.The development of safe and effective GI tract radioprotectants still remains a great challenge clinically.Here,we firstly report an oral radio...
Ionizing radiation caused by medical treatments,nuclear events or even space flights can irreversibly damage structure and function of brain cells.That can result in serious brain damage,with memory and behavior disor...
BACKGROUND Human Wharton’s jelly-derived mesenchymal stromal/stem cells(hWJ-MSCs)have gained considerable attention in their applications in cell-based therapy due to several advantages offered by them.Recently,we re...
The authors are thankful to the Center for Marine Bioproducts Development(CMBD)of Flinders University for providing the facility;The authors thank the Australian Research Council(ARC LP150100225);Gather Great Ocean Group,and Shanxi Tianzhirun Jujube Co Ltd.,China,Australian Kelp Products Pty Ltd.,Australia for their collaboration with the CMBD and the financial support.
Natural extracts and compounds from marine resources have gained intensive scientific and industry attention for radio-protective activities in the past ten years.However,the marine-derived radioprotectants have been ...
the National Key Rescarch and Development Program of China Stem Cell and Translational Research(2017YFA0104900,2016YFA0100600,and 2019YFA0110203);CAMS Initiative for Innovative Medi-cine(CAMS-12M)(2016-I2M-1-017 and 2017-I2M-1-015);CAMS Fundamental Rescarch Funds for Central RescarchInstitutes(2019PT320017);the National Natural ScienceFoundation of China(81670105,81970119,and 81421002).
Radioprotection was previously considered as a function of hematopoietic stem cells(HSCs).However,recent studies have reported its activity in hematopoietic progenitor cells(HPCs).To address this issue,we compared the...