MEBENDAZOLE

作品数:10被引量:3H指数:1
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相关领域:医药卫生农业科学更多>>
相关作者:李朝军更多>>
相关机构:新疆医科大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Pharmacy and Pharmacology》《Asian Journal of Pharmaceutical Sciences》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis
《Acta Pharmacologica Sinica》2019年第12期1568-1577,共10页Xue-han Chen Yu-jia Xu Xiao-ge Wang Peng Lin Bi-yin Cao Yuan-ying Zeng Qi Wang Zu-bin Zhang Xin-liang Mao Tie Zhang 
the National Natural Science Foundation of China(81320108023 to XM,81600171 to ZZ,and 81770215 to BC);the Natural Science Foundation of Jiangsu Higher Education Institutes of China(17KJA180010 to XM);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD to XM);the Jiangsu Key Laboratory for Neuro-Psycho-Diseases(BK2013003 to XM);The study was also partly supported by the Suzhou Key Laboratory for Pediatric Leukemia(SZS201615 to XM);the Suzhou Key Medical Center(Szzx201506 to YZ).
c-Maf is a critical oncogenic transcription factor that contributes to myelomagenesis.Our previous studies demonstrated that the deubiquitinase USP5 stabilizes c-Maf and promotes myeloma cell proliferation and surviva...
关键词:C-MAF USP5 MEBENDAZOLE multiple myeloma UBIQUITINATION 
Effect of Albendazole and Mebendazole on Hydatid Cyst of Mice
《Open Journal of Epidemiology》2017年第4期307-316,共10页Ekram Ismail Fagiree Ismail Mohammed Bahaa Eldeen Ahmed Saad Aisha Abass Elsadig 
In the current study, hydatid cysts from livers and lungs of camels were obtained from Tambool slaughter house and protoscoleces were separated aseptically. 36-weeks-old Swiss mice (25 - 30 gram body weight males and ...
关键词:HYDATID CYST MEBENDAZOLE ALBENDAZOLE 
Physicochemical Characterization and Solubility Enhancement Studies of Mebendazole Solid Dispersions in Solvent Mixtures
《Journal of Pharmacy and Pharmacology》2016年第7期351-358,共8页Pefia Maria Angeles Escalera Begofia Torrado Guillermo Natalini Paola 
Abstract: The objective was to obtain solid dispersion to improve the dissolution rate, solubility and oral absorption of MB (mebendazole), poor water-soluble drugs. The new formulation was characterized by DSC (d...
关键词:MEBENDAZOLE PVP K30 SOLUBILITY solid dispersion solubility parameter. 
Development of nanocrystal formulation of mebendazole with improved dissolution and pharmacokinetic behaviors
《Asian Journal of Pharmaceutical Sciences》2016年第1期122-123,共2页Naofumi Hashimoto Kayo Yuminoki Haruka Takeuchi Chiaki Okada 
Nanosizing by wet beads milling is a method to improve the solubility of poorly water soluble compounds[1,2].Mebendazole(MBZ)is a well-known anthelmintic drug in wide clinical use.There were some reports that MBZ had ...
关键词:MEBENDAZOLE Nanocrystal WET BEADS MILLING ORAL absorption 
Disseminated toxocariasis in an immunocompetent host
《Asian Pacific Journal of Tropical Biomedicine》2014年第10期838-840,共3页Madan Raj Aryal Paras Karmacharya Amrit Pokharel Smith Giri Ranjan Pathak Richard Alweis 
Toxocariasis is a zoonotic infection caused by Toxocara canis,or less commonly,Toxocara cati,which is one of the most common zoonotic infections worldwide.It commonly affects the pediatric and immunocompromised popula...
关键词:TOXOCARIASIS TOXOCARA CANIS MEBENDAZOLE ALBENDAZOLE 
New Crystalline Forms of Mebendazole with n-Alkyl Carboxylic Acids Neutral and Ionic Status
《Chinese Journal of Chemistry》2013年第5期635-640,共6页Jiamei Chen Tongbu Lu 
Structural information on the crystalline forms of mebendazole, an anti-parasitic drug, is limited, although three polymorphic forms of this drug have been reported. The present work investigates the structures and pr...
关键词:crystal engineering hydrogen bond supramolecular synthon crystalline form MEBENDAZOLE 
Current status of the efficacy and effectiveness of albendazole and mebendazole for the treatment of Ascaris lumbricoides in North-Western Indonesia被引量:1
《Asian Pacific Journal of Tropical Medicine》2012年第8期605-609,共5页Inke Nadia Diniyanti Lubis Syahril Pasaribu Chairuddin Panusunan Lubis 
Objective:To investigate the efficacy and effectiveness of albendazole and mebendazole in the treatment of Ascaris lumbricoides(A.lumbricoides) in the North-Western Indonesia.Methods: 229 primary school children who w...
关键词:ASCARIS lumbricoides ALBENDAZOLE MEBENDAZOLE DRUG resistance 
In vitro activities of acetonic extracts from leaves of three forage legumes(Calliandra calotyrsus,Gliricidia sepium and Leucaena diversifolia) on Haemonchus contortus被引量:2
《Asian Pacific Journal of Tropical Medicine》2011年第2期125-128,共4页Wabo Pone J Kenne Tameli Florence Mpoame Mbida Pamo Tedonkeng E Bilong Bilong CF 
Objective:To assess ovicidal activity of three acetonic extracts from the leaves of three forage legume,Calliandra calotyrsus(C.calotyrsus),Gliricidia sepium(G.sepium) and Leucaena diversifolia(L.diversifolia) in vitr...
关键词:Extract CALLIANDRA calotyrsus GLIRICIDIA sepium LEUCAENA diversifolia MEBENDAZOLE HAEMONCHUS contortus Cameroon 
Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children
《World Journal of Gastroenterology》2006年第39期6366-6370,共5页Roberto Caete Angel A Escobedo María E González Pedro Almirall 
AIM: To compare the efficacy and safety of five days apostrophe therapy of mebendazole (MBZ) versus quinacrine (QC) on human giardiasis in children.METHODS: A clinical trial was carried out in paediatric patien...
关键词:Giardia infection/drug therapy CHILDREN Me- bendazole/therapeutic use Quinacrine/therapeutic use Benzimidazoles/therapeutic use Giardiasis/drug therapy Cuba 
THE EVALUATION OF THE EFFECT OF MEBENDAZOLE ON TREATING ASCARIS LUMBRICOIDES AND TRICHURIS TRICHURA INFECTION WITH TWO KINDS OF THERAPY
《Journal of Pharmaceutical Analysis》1994年第1期60-62,66,共4页魏润民 熊印纲 魏平 杜贤彦 徐波 
A total of 309 cases infected with ascariasis and trichuriasis were selected as subjects, of whom 177 cases received mebendazole tablet 500mg/d for the treatment of ascariasis and trichuriais,132 cases received mebend...
关键词:Trichuris trichura ascaris lumbricoides MEBENDAZOLE EVALUATION 
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