Glutathione(GSH),a tripeptide that is present in all mammalian tissues,is especially highly concentrated in the liver.GSH synthesis occurs via two adenosine triphosphate(ATP)-requiring enzymatic steps:the first is rat...
the Natural Science Foundation of Hubei Province(No.2018CFC819);Health Commission of Hubei Province Scientific Research Project(No.WJ2019F163 and No.WJ2019F165).
MiRNAs are integral for maintaining immune homeostasis and self-tolerance.In this study,qPCR analyses were performed to determine which miRNAs play an important role in wound healing.Next,an experiment in a model of w...
the National Natural Science Foundation of China(81320108023 to XM,81600171 to ZZ,and 81770215 to BC);the Natural Science Foundation of Jiangsu Higher Education Institutes of China(17KJA180010 to XM);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD to XM);the Jiangsu Key Laboratory for Neuro-Psycho-Diseases(BK2013003 to XM);The study was also partly supported by the Suzhou Key Laboratory for Pediatric Leukemia(SZS201615 to XM);the Suzhou Key Medical Center(Szzx201506 to YZ).
c-Maf is a critical oncogenic transcription factor that contributes to myelomagenesis.Our previous studies demonstrated that the deubiquitinase USP5 stabilizes c-Maf and promotes myeloma cell proliferation and surviva...