云南高校图书馆联盟文献共享服务平台- JUNB

JUNB: 作品数：44被引量：95H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：宋涛郭成杨雪张雷刘青光更多>>; 相关机构：厦门大学中南大学汕头大学西安交通大学医学院第一附属医院更多>>; 相关期刊：《海南医学》《Science Bulletin》《癌变．畸变．突变》《细胞与分子免疫学杂志》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中央高校基本科研业务费专项资金山东省医药卫生科技发展计划项目更多>>

EGCG alleviates vascular calcification via the MAPK/JunB signaling pathway: 《Genes & Diseases》2025年第1期89-92,共4页Tiantian Li Fei Fang Hongmei Yin Zhen Zhang Xiangxiu Wang Erxiang Wang Hongchi Yu Yang Shen Guixue Wang Weihong He Xiaoheng Liu; supported by the National Natural Science Foundation of China(No.11932014,12372315,31971239);Sichuan Science and Technology Program(Sichuan,China)(No.2022NSFSC0765,2022ZYD0079,2023YFS0297);Science and Technology Innovation Project of JinFeng Laboratory,Chongqing,China(No.jfkyjf202203001).; Vascular calcification is a pathophysiological change characterized by abnormal deposition of hydroxyapatite crystals in the vascular walls,contributing to increased morbidity and mortality from cardiovascular disease...; 关键词：INHIBITING CALCIFICATION restrain

SF3B1/FOXM1/JUNB轴调控SOX21表达对宫颈癌细胞生物学行为的影响研究: 《成都医学院学报》2025年第1期1-5,10,共6页高洁阿依努尔·色义提谢丽夏依拉·艾合买提侯友翔; 国家自然基金地区科学基金项目(No:82260520,No:81860528)。; 目的分析剪接因子3B亚基1/叉头框转录因子M1/转录因子活化蛋白激酶B(SF3B1/FOXM1/JUNB)轴调控转录因子21抗体(SOX21)表达对宫颈癌细胞生物学行为的影响。方法选取2022年3月至2023年12月新疆医科大学附属肿瘤医院收治的50例宫颈癌患者的...; 关键词：剪接因子3B亚基1/叉头框转录因子M1/转录因子活化蛋白激酶B 转录因子21抗体宫颈癌细胞迁移侵袭增殖

Growth differentiation factor 7 alleviates the proliferation and metastasis of hepatocellular carcinoma: 《Liver Research》2024年第4期259-268,共10页Jianyong Zhuo Huigang Li Peiru Zhang Chiyu He Wei Shen Xinyu Yang Zuyuan Lin Runzhou Zhuang Xuyong Wei Shusen Zheng Xiao Xu Di Lu; the National Key Research and Development Programof China(No.2021YFA1100500);the Major Research Plan of the National Natural Science Foundation of China(No.92159202);the Key Research&Development Plan of Zhejiang Province(No.2021C03118);the National Natural Science Foundation of China(No.82303387 and No.82300742);the Natural Science Foundation of Zhejiang Province(No.LQ23H160048 and No.LQ22H160052);the Health Science&Technology Plan of Zhejiang Province(No.2022RC060);supported by the Construction Fund of Medical Key Disciplines of Hangzhou(No.OO20200093).; Background and aims:Inflammatory factors play significant roles in the development and occurrence of hepatocellular carcinoma(HCC).However,the tumor-protective functions of growth differentiation factors(GDFs)in HCC a...; 关键词：Hepatocellular carcinoma(HCC) Growth differentiation factor 7(GDF7) JunB proto-oncogene(JUNB) Epithelial-mesenchymal transition(EMT) PROLIFERATION METASTASIS

MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB: 《Signal Transduction and Targeted Therapy》2024年第11期5267-5285,共19页Xiujian Wang Xiao Tao Pengjie Chen Penglei Jiang Wenxiao Li Hefeng Chang Cong Wei Xinyi Lai Hao Zhang Yihan Pan Lijuan Ding Zuyu Liang Jiazhen Cui Mi Shao Xinyi Teng Tianning Gu Jieping Wei Delin Kong Xiaohui Si Yingli Han Huarui Fu Yu Lin Jian Yu Xia Li Dongrui Wang Yongxian Hu Pengxu Qian He Huang; supported by the National Key Research and Development Program of China(2022YFA1103500 to P.Q.);the National Key Nature Science Foundation of China(82130003 to H.H.);the Key Project of Science and Technology Department of Zhejiang Province(2019C03016 and 2020C03G2013586 to H.H.,Z24H080001 to P.Q.);the National Natural Science Foundation of China(82200248 and 82000194 to H.H.,82222003 and 82161138028 to P.Q.);the Key R&D Program of Zhejiang(2024SSYS0023 to H.H.,2024SSYS0024 to P.Q.,2024SSYS0025 to Y.H.);the Fundamental Research Funds for the Central Universities(226-2024-00007 to P.Q.).; Clinical evidence supports the notion that T cell exhaustion and terminal differentiation pose challenges to the persistence and effectiveness of chimeric antigen receptor-T(CAR-T)cells.MEK1/2 inhibitors(MEKIs),widely...; 关键词：JUNB metabolism STIMULATION

Galectin 3-binding protein(LGALS3BP)depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1(TGF-β1)availability and inhibits hepatocarcinogenesis: 《Cancer Communications》2024年第10期1106-1129,共24页Dae-Hwan Kim Minjeong Sung Myong-Suk Park Eun-Gene Sun Sumin Yoon Kyung Hyun Yoo Kamalakannan Radhakrishnan Sung Yun Jung Woo-Kyun Bae Sang-Hee Cho Ik-Joo Chung; Bio&Medical Technology Development Program of the National Research Foundation,Grant/Award Numbers:NRF-2020M3A9G3080281,NRF-2020R1A5A2031185;Korean Government。; Background:Increased Galectin 3-binding protein(LGALS3BP)serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma(HCC).Considering the crucial role of transforming gro...; 关键词：F-ACTIN FAK hepatic carcinogenesis IntegrinαV Interferonα JUNB LGALS3BP metabolic dysfuntion-associated steatohepatitis tensile force TGF-Β1

绿茶多酚EGCG通过调控转录因子JunB抑制血管钙化: 《医用生物力学》2024年第S01期353-353,共1页李甜甜房飞李春丽王尔祥杨涵荞刘肖珩; 国家自然科学基金项目,12372315,11932014;四川省科技计划项目,2022NSFSC0765,2022ZYD0079; 目的血管钙化是钙磷等羟基磷灰石晶体在血管壁的异常沉积,增加了心血管疾病的发病率和死亡率。目前,针对血管钙化还缺乏有效的治疗方法。绿茶多酚,表没食子儿茶素没食子酸酯(EGCG)对心血管系统有积极的保护作用,但补充EGCG是否会抑制血...; 关键词：血管钙化鼠主动脉心血管系统绿茶多酚主动脉环慢性肾病心血管疾病 VIT

电针心经穴位对急性心肌缺血模型大鼠内侧隔核白细胞介素-2、JunB蛋白及c-fos表达水平的影响: 《安徽中医药大学学报》2024年第2期38-42,共5页李锦航周美启; 国家自然科学基金项目(81674058)。; 目的观察电针心经对急性心肌缺血(acute myocardial ischemia,AMI)大鼠内侧隔核白细胞介素(interleukin,IL)-2水平、JunB蛋白及c-fos表达水平的影响,探究内侧隔核在针刺抗AMI中的作用及机制。方法将大鼠分为伪手术组、模型组和电针组,每...; 关键词：急性心肌缺血内侧隔核 JunB蛋白 C-FOS 电针

Jianpi Qinghua Formula Alleviates Diabetic Myocardial Injury Through Inhibiting JunB/c-Fos Expression: 《Current Medical Science》2024年第1期144-155,共12页Lin WANG Qing-guang CHEN Hao LU; supported by grants from the National Natural Science Foundation of China(No.81874434 and No.81804053);Yangtze River Delta Traditional Chinese Medicine Endocrinology and Metabolic Disease Specialist Alliance(No.ZY2021-2023-0302).; Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,m...; 关键词：Jianpi Qinghua formula diabetic cardiomyopathy AP-1 transcription factor apoptosis inflammation

JunB condensation attenuates vascular endothelial damage under hyperglycemic condition: 《Journal of Molecular Cell Biology》2023年第12期34-49,共16页Xuxia Ren Zexu Cui Qiaoqiao Zhang Zhiguang Su Wei Xu Jinhui Wu Hao Jiang; supported by grants from the National Natural Science Foundation of China(32090043 and 31771505);the National Key Research and Development Program of China(2017YFC0840101 and 2018YFA0108302);Sichuan Science and Technology Program,the Central Government Guides Local Science and Technology Development Projects(2022ZYD0078);Sichuan Science and Technology Program(2023YFQ0008);Science and Technology Department of Tibet,the Central Government Guides Local Science and Technology Development Projects(XZ202102YD0026C);the 1.3.5 Project for Disciplines of Excellence(ZYYC20001,ZYGD20010,and ZY2017201);the Project of Max Cynader Academy of Brain Workstation,WCHSCU(HXYS19005);the National Clinical Research Center for Geriatrics(Z20191011,Z20201009,and Z2023YY003).; Endothelial damage is the initial and crucial factor in the occurrence and development of vascular complications in diabetic patients,contributing to morbidity and mortality.Although hyperglycemia has been identified ...; 关键词：HYPERGLYCEMIA JUNB phase separation endothelial damage

JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis被引量：5: 《Acta Biochimica et Biophysica Sinica》2023年第11期1784-1796,共13页Suyao Li Yichou Wei Xun Sun Mengling Liu Mengxuan Zhu Yitao Yuan Jiayu Zhang Yu Dong Keshu Hu Sining Ma Xiuping Zhang Bei Xu Hesheng Jiang Lu Gan Tianshu Liu; supported by the grants from the Foundation of Shanghai Science and Technology Committee (No.19DZ1910102);the Natural Science Foundation of Shanghai (No.23ZR1421300).; tients,and chemotherapy resistance is one of the main reasons for treatment failure.Thus,it is important to reveal the mechanism of oxaliplatin resistance and to seek effective intervention strategies to improve chemo...; 关键词：gastric cancer JUNB ATAC-seq oxaliplatin resistance MAPK signaling pathway chromatin accessibility

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