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Bioprinting of inorganic-biomaterial/neural-stem-cell constructs for multiple tissue regeneration and functional recovery被引量：1: 《National Science Review》2024年第4期222-238,共17页Hongjian Zhang Chen Qin Zhe Shi Jianmin Xue Jianxin Hao Jinzhou Huang Lin Du Hongxu Lu Chengtie Wu; This work was supported by the National Key Research and Development Program of China(2023YFB3813000);the National Natural Science Foundation of China(32225028 and 32130062);the Chinese Academy of Sciences Project for Young Scientists in Basic Research(YSBR073);the Shanghai Pilot Program for Basic Research-Chinese Academy of Sciences,Shanghai Branch(JCYJ-SHFY-2022-003);the project supported by the Space Application System of the China Manned Space Program.; Tissue regeneration is a complicated process that relies on the coordinated effort of the nervous,vascular and immune systems.While the nervous system plays a crucial role in tissue regeneration,current tissue enginee...; 关键词：3D bioprinting neural stem cells inorganic biomaterials neural constructs multiple tissue regeneration

Biological scaffold as potential platforms for stem cells:Current development and applications in wound healing: 《World Journal of Stem Cells》2024年第4期334-352,共19页Jie-Yu Xiang Lin Kang Zi-Ming Li Song-Lu Tseng Li-Quan Wang Tian-Hao Li Zhu-Jun Li Jiu-Zuo Huang Nan-Ze Yu Xiao Long; Supported by CAMS Innovation Fund for Medical Sciences,No.2020-I2M-C&T-A-004;National High Level Hospital Clinical Research Funding,No.2022-PUMCH-A-210,No.2022-PUMCH-B-041,and No.2022-PUMCH-C-025;and National Key R&D Program of China,No.2020YFE0201600.; Wound repair is a complex challenge for both clinical practitioners and researchers.Conventional approaches for wound repair have several limitations.Stem cell-based therapy has emerged as a novel strategy to address ...; 关键词：Stem-cell-based therapy Biological scaffolds Wound healing Extracellular matrix mimicry Cellular activities enhancement Scaffold characteristics

Self-organization principles in stem-cell-derived synthetic embryo models被引量：1: 《The Innovation》2023年第1期20-21,共2页Min Bao; As embryos,we were extremely lucky to survive implantation,when we transitioned from a simple ball of undifferentiated cells to a complex structure of distinct lineages.During development,fertilization generates a tot...; 关键词：IMPLANTATION initially OUTSIDE

Surgical management of monomorphic epitheliotropic intestinal Tcell lymphoma followed by chemotherapy and stem-cell transplant:A case report and review of the literature被引量：1: 《World Journal of Gastrointestinal Oncology》2022年第11期2273-2287,共15页Abdul Saad Bissessur Ji-Chun Zhou Ling Xu Zhao-Qing Li Si-Wei Ju Yun-Lu Jia Lin-Bo Wang; BACKGROUND Monomorphic epitheliotropic intestinal T-cell lymphoma(MEITL)is a rare and rapidly progressive intestinal T-cell non-Hodgkin lymphoma associated with a very poor prognosis and a median survival of 7 mo.Adva...; 关键词：Monomorphic epitheliotropic intestinal T-cell lymphoma Gastrointestinal stromal tumor Immunophenotypically CHEMOTHERAPY Stem-cell transplant Case report

Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles被引量：4: 《World Journal of Stem Cells》2022年第7期453-472,共20页Victoria Pulido-Escribano Bárbara Torrecillas-Baena Marta Camacho-Cardenosa Gabriel Dorado MaríaÁngeles Gálvez-Moreno Antonio Casado-Díaz; Supported by “Instituto de Salud Carlos III”(ISCIII);“Ministerio de Economía y Competitividad”(MINECO) and European Union (EU),No. PI18/01659 and No. PI21/01935; The use of mesenchymal stem-cells(MSC)in cell therapy has received considerable attention because of their properties.These properties include high expansion and differentiation in vitro,low immunogenicity,and modulat...; 关键词：Cell priming Extracellular vesicles HYPOXIA Hypoxia-inducible factor Mesenchymal stemcells Regenerative medicine

Higher efficacy of oral etoposide for mobilization of peripheral blood stem cells in patients with multiple myeloma: 《Blood Science》2022年第2期76-82,共7页Wanting Qiang Hua Jiang Pei Guo Jing Lu Jin Liu Lu Li Haiyan He Xiaoxia Hu Weijun Fu Juan Du; This work was supported in part by the National Natural Science Foundation of China(NFSC 81372543,NFSC 81870164).; This study compares the efficacy,toxicity,hematopoietic recovery,and cost of stem-cell mobilization using intermediate-dose cyclophosphamide(IDCy)plus granulocyte colony-stimulating factor(G-CSF)compared with etoposid...; 关键词：APHERESIS ETOPOSIDE Intermediate-dose cyclophosphamide Multiple myeloma ORAL Peripheral blood stem-cell mobilization

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair被引量：2: 《National Science Review》2022年第4期111-122,共12页Shenqiang Wang Letao Yang Bolei Cai Fuwei Liu Yannan Hou Hua Zheng Fang Cheng Hepeng Zhang Le Wang Xiaoyi Wang Qianxin Lv Liang Kong Ki-Bum Lee Qiuyu Zhang; financial support from the National Natural Science Foundation of China (51673156);funding support from the National Natural Science Foundation of China (82171568);funding support from the National Natural Science Foundation of China (82171009);the Fundamental Research Funds for the Central Universities(310201911fz051);the Science and Technology Project of Shenzhen (JCYJ20190806155814624);funding support from the New Jersey Commission on Spinal Cord Research (CSCR17IRG010 and CSCR16ERG019)。; Cartilage injuries are o?ten devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repa...; 关键词：injectable nanoscaffold 3D cell culture tissue engineering cartilage repair stem-cell therapy

Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy:long-term results from a non-randomised,open-label,phase 1/2 trial and expanded access: 《四川生理科学杂志》2021年第11期2002-2002,共1页Francesca Fumagalli; Background:Effective treatment for metachromatic leukodystrophy(MLD)remains a substantial unmet medical need.In this study we investigated the safety and efficacy of atidarsagene autotemcel(arsa-cel)in patients with M...; 关键词：DYSTROPHY diagnosis expanded

Empty nose syndrome pathogenesis and cell-based biotechnology products as a new option for treatment: 《World Journal of Stem Cells》2021年第9期1293-1306,共14页Inna M Gordiienko Olga S Gubar Roman Sulik Taras Kunakh Igor Zlatskiy Alona Zlatska; Empty nose syndrome (ENS) is a rare complication that develops after partial orcomplete turbinectomy. The main feature of ENS is paradoxical nasal obstructionfeeling despite objectively wide nasal airway. ENS pathogen...; 关键词：Empty nose syndrome Stem-cell-based technologies Implants biomaterials GRAFTS HYDROGELS Mesenchymal stem cells

Printed elastic membranes for multimodal pacing and recording of human stem-cell-derived cardiomyocytes: 《npj Flexible Electronics》2020年第1期109-116,共8页Markos Athanasiadis Dzmitry Afanasenkau Wouter Derks Christoph Tondera Francesca Murganti Volker Busskamp Olaf Bergmann Ivan R.Minev; We acknowledge funding from Volkswagen Foundation(Freigeist 91690);ERC starting grant(804005‐IntegraBrain)and Center for Advancing Electronics Dresden(cfaed).V.B.was supported by the Volkswagen Foundation(Freigeist A110720);by an ERC starting grant(678071-ProNeurons).; Bioelectronic interfaces employing arrays of sensors and bioactuators are promising tools for the study,repair and engineering of cardiac tissues.They are typically constructed from rigid and brittle materials process...; 关键词：RECORDING MODAL CLOSER

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