相关期刊:《International Journal of Organic Chemistry》《Journal of Agricultural Chemistry and Environment》《Organic Chemistry Frontiers》《Science China Chemistry》更多>>
Nicotine is an alkaloid mainly found in leaves of tobacco and is used therapeutically for patients seeking relief from tobacco dependence in the form of products such as gums, patches, lozenges etc. In these products,...
the Marie Skłodowska-Curie actions for an Individual Fellowship(V.C.,GA No.702385);the Leverhulme Trust for funding(H.G.G.,RPG-2015-003);the EPSRC for additional support(EP/S013172/1).
As products of genome mining,the stereochemical assignment of the macrolide antibiotics stambomycins A-D has been made on the basis of sequence analysis of the associated polyketide synthase,aside from two stereocentr...
support from the National Natural Science Foundation of China(21931010);the National Key R&D Program of China(grant No.2017YFA0207302).
A seven-step total synthesis of(+)-cylindricine D and epi-cylindricine D is described.The efficiency relies on the highly diastereoselective reductive bis-functionalization of N,O-protected(S)-pyroglutaminol by our re...
The purpose of this study was to compare pharmacokinetic(PK)parameters obtained using two newly developed assays,HPLC-UV and UPLC-ESI-MS/MS.Selection of assay and results obtained therefrom are very important in PK st...
A direct enantio-,diastereo-,and chemo-selective high-performance liquid chromatographic method was developed for determining the content,enantiomeric purity,and related substances of the chiral antidepressant drug se...
Morpholine fungcides have certain antibacterial side effect, dodemorph being the most active among them. The diequatorial (cis-)?form of dodemorph expressed higher antibacterial activity than the axial-equatorial (tra...
supported by USA NIH(GM095086);the Georgia Cancer Coalition(GCC) Distinguished Cancer Clinicians and Scientists;USA National Science Foundation(MCB-0824837)
Modified deoxy-and ribo-nucleoside triphosphates are chemically synthesized in multiple steps due to the protection and deprotection of the nucleoside functionalities.To conveniently synthesize the S-modified triphosp...
financially supported by National Water Pollution Control and Management Technology Major Projects(No.2009ZX07210-009);Scientific and Technological Developing Project of Shandong Province(No. 2009GG20001021-9);Open Research Fund Program of Shandong Provincial Key Laboratory of Eco-Environmental Science for Yellow River Delta(No.2009KFJJ01);Basic Foundation of Shandong Academy of Sciences and Analysis and Test center of Shandong province
A novel temperature controlled ionic liquid dispersive liquid phase microextracfion (TCIL-DLPME) coupled with rapid resolution liquid chromatography-electrospray tandem mass spectrometry (RRLC-ESI-MS-MS) has been ...
Keeping in view the biological activities of 1,3,2-dioxaphosphorinane-2-one and oxime esters. some compounds possessing these two moieties have been synthesized. The configurational assignment and the ratio of cis/tra...