[Objectives]To optimize the water extraction process of Fagopyri Dibotryis Rhizoma.[Methods]The entropy weight method was used to determine the weight of epicatechin extraction rate and dry extract rate and calculate ...
supported by the National Key Research and Development Program of China under Grant(2022YFF1102800);the Graduate Scientific Research Innovation Project of Tianji(2022SKY109);the Project of Tianjin Science and Technology Program(22JCYBJC00360);the Project of Tianjin Science and Technology Program(21ZYJDJC00060)。
Epicatechin(EC)was used in this study to antagonize the cognitive dysfunction caused by lead(Pb)exposure in mice.Eight-week-old male Kunming mice were treated with PbCl_(2)(20 mg/kg)and/or EC(50 mg/kg)by gavage admini...
Coronavirus disease-19(COVID-19)is the ongoing pandemic affecting millions of people worldwide.Several vaccine candidates have been designed and developed for the causative virus,SARS-CoV-2.However high mu-tation rate...
This work was supported financially by National Natural Science Foundation of China(NSFC)(NO.32172234);national food science and engineering first-class discipline construction project(NO.JUFSTR20180204,China);the national key research and development plan in the 13th Five-Year(NO.2017YFD0400803,China).
(-)-Epicatechin gallate(ECG),as a naturalα-amylase inhibitor,has received extensive attention.However,poor liposolubility of ECG limits its application.In this study,lipophilic derivatives of ECG(1A-ECG,2A-ECG,1B-ECG...
This work was supported by College Students Innovation and Entrepreneurship Training Program in 2021(No.202110163003).
Epicatechin gallate(ECG)is one of the polyphenolic compounds and has attracted much attention due to its various bioactivities.In this study,the neuroprotective eff ect of ECG against H_(2)O_(2)-induced oxidative inju...
This work was financially supported by College Students Innovation and Entrepreneurship Training Program in 2021(No.202110163009).
An efficient method for producing trimeric procyanidin C1(PCC1)was developed through degradation of grape seed polymeric procyanidins(PPCs),using epicatechin(EC)as nucleophile and hydrochloric acid as catalyst.With th...
Catechin and epicatechin are two isomeric flavonoids. Despite the vital properties highlighted by numerous scientific studies, very little data is available on the intrinsic reactivity of these compounds. To provide m...
funded by Hubei Science and Technology Plan Key Project(G2019ABA100);Open fund of Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization(201932103);fund from Assessment and Comprehensive Utilization of Characteristic Biological resources in Dabie Mountains(4022019006)。
(–)-Epicatechin-3-gallate(ECG),a bioactive polyphenolic compound,has contributed a lot to the health benefits of green tea.Great attention has been focused on(–)-epigallocatechin-3-gallate(EGCG),but limited research...
This work was supported by the grants from the National Natural Science Foundation of China(Nos.81703828,81873100 and 81673732);the research and innovation project of graduate students in the Tianjin University of Traditional Chinese Medicine(No.YJSKC-20191023).
Lipid metabolism disorder caused by the upregulation of lipogenic genes is a typical feature of prostate cancer.The synthesis of fatty acids is enhanced to accelerate the development of prostate cancer and is consider...
Natural Sciences Foundation of China(NSFC,Grant No.81872913);National High-tech R&D Program(863 Program,Grant No.2015AA020911)。
Theβ-lactam antibiotic resistance caused by NDM-1 has become a major crisis of global public health.We have previously screened out(-)-epicatechin gallate(ECG)as a potent NDM-1 inhibitor.We further discussed its inhi...