EPICATECHIN

作品数:23被引量:28H指数:3
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相关领域:医药卫生轻工技术与工程更多>>
相关作者:张泽萍马云保漆淑华吴大刚罗晓东更多>>
相关机构:中国科学院郑州大学贵州医科大学华中科技大学更多>>
相关期刊:《Chinese Herbal Medicines》《Medicinal Plant》《Mechanobiology in Medicine》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金中国科学院西部之光基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Optimization of Extraction Process of Fagopyri Dibotryis Rhizoma by Orthogonal Experiment
《Medicinal Plant》2024年第3期26-29,共4页Jian YU 
[Objectives]To optimize the water extraction process of Fagopyri Dibotryis Rhizoma.[Methods]The entropy weight method was used to determine the weight of epicatechin extraction rate and dry extract rate and calculate ...
关键词:Fagopyri Dibotryis Rhizoma ORTHOGONAL EXPERIMENT EPICATECHIN DRY EXTRACT 
Epicatechin attenuates lead(Pb)-induced cognitive impairment in mice:regulation on Nrf2 signaling pathway,and interference on the interaction between Pb with albumin
《Food Science and Human Wellness》2024年第2期1065-1078,共14页Dai Cheng Qianqian Yu Kexin Zhu Dingdong Bu Zijian Wu 
supported by the National Key Research and Development Program of China under Grant(2022YFF1102800);the Graduate Scientific Research Innovation Project of Tianji(2022SKY109);the Project of Tianjin Science and Technology Program(22JCYBJC00360);the Project of Tianjin Science and Technology Program(21ZYJDJC00060)。
Epicatechin(EC)was used in this study to antagonize the cognitive dysfunction caused by lead(Pb)exposure in mice.Eight-week-old male Kunming mice were treated with PbCl_(2)(20 mg/kg)and/or EC(50 mg/kg)by gavage admini...
关键词:LEAD EPICATECHIN Bovine serum albumin Interaction Oxidative stress 
In silico study unfolds inhibitory potential of epicatechin gallate against SARS-CoV-2 entry and replication within the host cell
《Mechanobiology in Medicine》2023年第2期54-66,共13页Prem Rajak Abhratanu Ganguly 
Coronavirus disease-19(COVID-19)is the ongoing pandemic affecting millions of people worldwide.Several vaccine candidates have been designed and developed for the causative virus,SARS-CoV-2.However high mu-tation rate...
关键词:Epicatechin gallate FLAVONOIDS SARS-CoV-2 COVID-19 Molecular docking 
Synthesis of ECG ((-)-epicatechin gallate) acylated derivatives as new inhibitors of α-amylase and their mechanism on delaying starch digestion
《Food Bioscience》2023年第2期1018-1027,共10页Shan Wang Chao Jiang Huijuan Jing Xiaojing Du Song Zhu Hongxin Wang Chaoyang Ma 
This work was supported financially by National Natural Science Foundation of China(NSFC)(NO.32172234);national food science and engineering first-class discipline construction project(NO.JUFSTR20180204,China);the national key research and development plan in the 13th Five-Year(NO.2017YFD0400803,China).
(-)-Epicatechin gallate(ECG),as a naturalα-amylase inhibitor,has received extensive attention.However,poor liposolubility of ECG limits its application.In this study,lipophilic derivatives of ECG(1A-ECG,2A-ECG,1B-ECG...
关键词:ECG derivatives Α-AMYLASE Fluorescence quenching Molecular docking Simulated digestion 
RNA-seq analysis of protective effect of epicatechin gallate on H_(2)O_(2)-induced oxidative injury in PC12 cells
《Journal of Polyphenols》2022年第1期1-16,共16页Nan Cheng Xinxin Lin Jiayue Xu Kai Wang Kaile Wang Zhengping Liu Parhat Kamel Fang Wang 
This work was supported by College Students Innovation and Entrepreneurship Training Program in 2021(No.202110163003).
Epicatechin gallate(ECG)is one of the polyphenolic compounds and has attracted much attention due to its various bioactivities.In this study,the neuroprotective eff ect of ECG against H_(2)O_(2)-induced oxidative inju...
关键词:epicatechin gallate H_(2)O_(2) oxidative injury RNA-SEQ cell cycle 
Efficient semisynthetic approach for large preparation of procyanidin C1 through degradation of grape seed polymeric procyanidins
《Journal of Polyphenols》2022年第1期32-41,共10页Qian Li Lina Zhang Danyang Wang Mengyao Zhao Baoshan Sun Shuting Zhang 
This work was financially supported by College Students Innovation and Entrepreneurship Training Program in 2021(No.202110163009).
An efficient method for producing trimeric procyanidin C1(PCC1)was developed through degradation of grape seed polymeric procyanidins(PPCs),using epicatechin(EC)as nucleophile and hydrochloric acid as catalyst.With th...
关键词:PROCYANIDINS EPICATECHIN DEGRADATION grape seed 
Catechin and Epicatechin. What’s the More Reactive?
《Computational Chemistry》2022年第2期53-70,共18页Essoh Akpa Eugène N’guessan Boka Robert Adenidji Ganiyou Yapo Kicho Denis Adjou Ané Bamba El Hadji Sawaliho 
Catechin and epicatechin are two isomeric flavonoids. Despite the vital properties highlighted by numerous scientific studies, very little data is available on the intrinsic reactivity of these compounds. To provide m...
关键词:CATECHIN EPICATECHIN NBO ACIDITY DFT Normal Modes 
Health promoting activities and corresponding mechanism of(–)-epicatechin-3-gallate
《Food Science and Human Wellness》2022年第3期568-578,共11页Zhiliang Li Changchun Feng Hongjin Dong Weibin Jin Wenying Zhang Jianfeng Zhan Shuzhen Wang 
funded by Hubei Science and Technology Plan Key Project(G2019ABA100);Open fund of Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization(201932103);fund from Assessment and Comprehensive Utilization of Characteristic Biological resources in Dabie Mountains(4022019006)。
(–)-Epicatechin-3-gallate(ECG),a bioactive polyphenolic compound,has contributed a lot to the health benefits of green tea.Great attention has been focused on(–)-epigallocatechin-3-gallate(EGCG),but limited research...
关键词:(-)-Epicatechin-3-gallate Polyphenolic compounds Pharmacological properties Anticarcinogenic agent Natural antioxidants Antimicrobial properties 
Epicatechin gallate prevents the de novo synthesis of fatty acid and the migration of prostate cancer cells被引量:2
《Acta Biochimica et Biophysica Sinica》2021年第12期1662-1669,共8页Luyao Chen Yaping Guo Zixuan Wu Shuwu Zhao Zhaiyi Zhang Fang Zheng Likang Sun Zheng Hao Chen Xu Tao Wang Yanfei Peng 
This work was supported by the grants from the National Natural Science Foundation of China(Nos.81703828,81873100 and 81673732);the research and innovation project of graduate students in the Tianjin University of Traditional Chinese Medicine(No.YJSKC-20191023).
Lipid metabolism disorder caused by the upregulation of lipogenic genes is a typical feature of prostate cancer.The synthesis of fatty acids is enhanced to accelerate the development of prostate cancer and is consider...
关键词:epicatechin gallate fatty acid synthesis MIGRATION prostate cancer 
(-)-Epicatechin gallate serves as a novel new delhi metallo-β-lactamase-1(NDM-1)inhibitor被引量:1
《Journal of Chinese Pharmaceutical Sciences》2021年第9期716-724,共9页Qian Wang Chennan Liu Jiangxue Han Sihan Liu Chunling Xiao Yan Guan Xinghua Li Ying Wang Xiao Wang Jianzhou Meng Maoluo Gan Yishuang Liu 
Natural Sciences Foundation of China(NSFC,Grant No.81872913);National High-tech R&D Program(863 Program,Grant No.2015AA020911)。
Theβ-lactam antibiotic resistance caused by NDM-1 has become a major crisis of global public health.We have previously screened out(-)-epicatechin gallate(ECG)as a potent NDM-1 inhibitor.We further discussed its inhi...
关键词:NDM-1 (-)-Epicatechin gallate INHIBITOR Antibiotics resistance 
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