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Lard reduces obesity in mice compared with corn oil and canola oil via modulating gut microbiota and bile acid metabolism
《Food Science and Human Wellness》2025年第3期1080-1091,共12页Wusun Li Weida Wu Yuhui Zhang Xiaoyan Tang Xin Zheng Xinyuan Huang 
funded by Basic Research Fund of Chinese Academy of Agricultural Sciences(CAAS)(1610072021001);the China Agriculture Research System(CARS-35);the Agricultural Science and Technology Innovation Program of CAAS。
The association between dietary fat types and obesity is controversial,and the underlying mechanism remains unclear.This study aimed to evaluate the effect of different dietary fat sources(lard,corn oil or canola oil)...
关键词：Dietary fats OBESITY LARD Gut microbiota Bile acid Farnesoid X receptor 
Unsaponifiable matter from walnut oil ameliorate memory deficits and mitochondrial dysfunction in aging mice via activating Nrf2 signaling pathway
《Food Science and Human Wellness》2025年第3期1127-1138,共12页Dan Hong Xiao Xiao Aijin Ma Zhou Chen Siting Li Junxia Xia Yiling Tian Yingmin Jia 
supported by the National Key Research and Development Program(2022YFD1600402);Hebei Provincial Major Science and Technology Achievement Transformation Project(21287101Z);Hebei Provincial Innovation and Entrepreneurship Team Project(215A7102D)。
Aging is an inevitable biological phenomenon that involves a multitude of physiological alterations.Dietary interventions are being considered as potential strategies for delaying age-related dysfunction.Unsaponifiabl...
关键词：Unsaponifiable matter Memory impairment mitochondrial dysfunctions Nrf2 signaling pathway Antioxidant stress 
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT
《Oncology Research》2025年第5期1121-1133,共13页WENYING ZHENG YANYAN SHANG KAI DU AILING LUO LIJUN PEI MEIQI LI GUOPING ZHANG MIN DENG 
supported by the National Natural Science Foundation of China(Nos.81972771,82173062);the Key Areas Project of Education Department of Guangdong Province(No.2021ZDZX2017);the Tertiary Education Scientific Research Project of Guangzhou Municipal Education Bureau(No.202235387);the Guangzhou Science and Technology Project of Guangzhou Municipal Science and Technology Bureau(No.2023A03J0428);the Natural Science Foundation of Guangdong Province,China(No.2024A1515013082);the Guangdong Basic and Applied Basic Research 21 Foundation(No.2021A1515010403).
Background:Alterations in splicing factors contribute to aberrant alternative splicing(AS),which subsequently promotes tumor progression.The splicing factor polypyrimidine tract binding protein 1(PTBP1)has been shown ...
关键词：Hepatocellular carcinoma Alternative splicing PTBP1 MAPT 
A Fuzzy Multi-Objective Framework for Energy Optimization and Reliable Routing in Wireless Sensor Networks via Particle Swarm Optimization
《Computers, Materials & Continua》2025年第5期2773-2792,共20页Medhat A.Tawfeek Ibrahim Alrashdi Madallah Alruwaili Fatma M.Talaat 
funded by Deanship of Graduate studies and Scientific Research at Jouf University under grant No.(DGSSR-2023-2-02038).
Wireless Sensor Networks(WSNs)are one of the best technologies of the 21st century and have seen tremendous growth over the past decade.Much work has been put into its development in various aspects such as architectu...
关键词：Wireless sensor networks particle swarm optimization fuzzy multi-objective framework routing stability 
策展式商业空间 打造属于南京路的全新集体记忆 via·1719吴良材新视场
《室内设计与装修》2025年第5期28-31,共4页无 云眠(摄影) 
当一座建筑成为一个城市的集体记忆时,它所承载的意义便与众不同;人们每每提及,总会分享与它互动的故事,回忆那个年代它最鲜明的变化——南京路上的七重天大厦正是这样一座饱含情感的老建筑。如今,大宛携手拥有三百年匠心与传统的老字...
关键词：南京路 集体记忆 大宛 七重天大厦 吴良材 
Effect of ranibizumab on diabetic retinopathy via the vascular endothelial growth factor/STAT3/glial fibrillary acidic protein pathway
《World Journal of Diabetes》2025年第5期234-253,共20页Ye-Ting Lin Jian Tan Yu-Lin Tao Wei-Wen Hu Yi-Cang Wang Jing Huang Qiong Zhou Ang Xiao 
Supported by the Natural Science Foundation of Jiangxi Province,No.20242BAB25489;National Natural Science Foundation of China,No.82260211 and No.81460092;Key Research and Development Project in Jiangxi Province,No.20203BBG73058;Chinese Medicine Science and Technology Project in Jiangxi Province,No.2020A0166。
BACKGROUND Diabetic retinopathy(DR)is the leading cause of vision loss in patients with diabetes.The vascular endothelial growth factor(VEGF)pathway plays a critical role in the pathogenesis of DR,and ranibizumab,an a...
关键词：Diabetic retinopathy RANIBIZUMAB Early stage Vascular endothelial growth factor Signal transducer and activator of transcription 3 Glial fibrillary acidic protein 
Inferring a spinning black hole in an expanding universe via the S2 star around the galactic center
《Chinese Physics C》2025年第4期249-258,共10页Jin-Tao Yao Xin Li 
Supported by the National Natural Science Foundation of China(12275034,12347101)。
The nearest black hole to Earth,Sagittarius A^(*)(Sgr A^(*)),with its intense gravitational field,provides a unique opportunity to explore black hole mysteries.Over the past few decades,monitoring of the S2 star has p...
关键词：spinning black hole equations of motion 2-body problem in General Relativity 
Prediction of perioperative complications in colorectal cancer via artificial intelligence analysis of heart rate variability
《World Journal of Gastrointestinal Surgery》2025年第4期290-299,共10页Miao-Miao Ge Li-Wen Wang Jun Wang Jiang Liu Peng Chen Xin-Xin Liu Gang Wang Guan-Wen Gong Zhi-Wei Jiang 
Supported by The Natural Science Foundation of Nanjing University of Chinese Medicine,No.XZR2021019;The Outstanding Young Doctor Program of Jiangsu Province of Chinese Medicine,No.2023QB0140;Project of National Clinical Research Base of Traditional Chinese Medicine in Jiangsu Province,No.JD2022SZ18;The Natural Science Foundation of Nanjing University of Chinese Medicine,No.KYCX21_1710.
BACKGROUND Heart rate variability(HRV)represents efferent vagus nerve activity,which is suggested to be related to fundamental mechanisms of tumorigenesis and to be a predictor of prognosis in various cancers.Therefor...
关键词：Colorectal cancer Heart rate variability COMPLICATIONS Perioperative period PREDICTION 
Hydrogen Sulfide Alleviates Lipid Peroxidation-Mediated Carbonyl Stress in Uranium-Intoxicated Kidney Cells via Nrf2/ARE Signaling
《Biomedical and Environmental Sciences》2025年第4期484-500,共17页Jialin Liu Min Wang Rui Zhang Jifang Zheng Xixiu Jiang Qiaoni Hu 
supported by the National Natural Science Foundation of China(No.82160627);the Natural Science Foundation of the Guangxi Autonomous Region(No.2020GXNFSAA297262)。
Objective To explore the protective effects and underlying mechanisms of H_2S against lipid peroxidation-mediated carbonyl stress in the uranium-treated NRK-52E cells.Methods Cell viability was evaluated using CCK-8 a...
关键词：Hydrogen sulfide(H_2S) Carbonyl stress Lipid peroxidation URANIUM NEPHROTOXICITY NRF2 
Attenuation of Richtmyer-Meshkov instability growth of fluid layer via double shock
《Science China(Physics,Mechanics & Astronomy)》2025年第4期144-151,共8页Chenren Chen Jiaxuan Li He Wang Zhigang Zhai Xisheng Luo 
supported by the National Natural Science Foundation of China(Grant Nos.12372281,12102425,12388101,and 123B2034);the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB0620201);the Youth Innovation Promotion Association CAS。
Suppression of the hydrodynamic instabilities involved in the inertial confinement fusion has attracted much attention but remains a challenge.In this work,we report the first theoretical analysis and experimental val...
关键词：shock waves Richtmyer-Meshkv instability fluid layer 
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