supported by the scholarships provided by São Paulo Research Foundation(FAPESP),No.2013/02371-6(to LANM),No.2013/01604-7(to SFGZP),No.2013/14353-2(to TFCFS),No.2015/06706-8(to LANM)and No.2019/15980-7(to MBD);financial support grants No.2013/26257-8;São Paulo Research Foundation(FAPESP)and No.307269/2017-5;the National Council for Scientific and Technological Development(CNPq),to AS.
Multiple sclerosis is an autoimmune treatable but not curable disease.There are a multiplicity of medications for multiple sclerosis therapy,including a class entitled disease-modifying drugs that are mainly indicated...
supported by a grant from Universidad Anahuac México Norte(No.201425)
Copolymer-1(Cop-1) is a peptide with immunomodulatory properties, approved by the Food and Drug Administration of United States in the treatment of multiple sclerosis. Cop-1 has been shown to exert neuroprotective e...
supported by Prémios Santa Casa Neurociências-Prize Meloe Castro for Spinal Cord Injury Research;Portuguese Foundation for Science and Technology(Financiado noambito do Projecto 3599-Promover a Producao Científica e Desenvolvimento Tecnológico e a Constituicao de Redes Temáticas(3599-PPCDT);project:PTDC/DTP-FTO/5109/2014;Post-Doctoral fellowship-SFRH/BPD/97701/2013-to N.A.Silva;IF Development Grant to A.J.Salgado
The initial trauma to the spinal cord is just the starting point for a cascade of endogenous events that will collectively determine the injury extension. These secondary events include, but are not limited to: gluta...
partially supported by the Zanvyl and Isabelle Krieger Fund,Baltimore,Maryland,USA;Israel Scientific Foundation,ISF(1189/12,NGC)
The promising role of cellular therapies in the preservation and restoration of visual function has prompted intensive efforts to characterize embryonic, adult, and induced pluripotent stem cells for regenerative purp...
Increasing evidence shows that extremely low frequency electromagnetic fields(ELF-EMFs) stimulation is able to exert a certain action on autoimmunity and immune cells. In the past, the efficacy of pulsed ELFEMFs in ...
supported by grants from the Shandong Province Science and Technology Program, GrantNo.2011GSF11801;the Innovation Fund Project of Shandong University, Grant No.2012ZD023;the Major StateBasic Research Development Program, Grant No.2012CB966504
The immunomodulatory and anti-oxidative activities of differentiated mesenchymal stem cells contribute to their therapeutic efficacy in cell-replacement therapy. Mesenchymal stem cells were isolated from human umbilic...
BACKGROUND: Humoral autoimmunity in patients with multiple sclerosis is often asymptomatic and transient during interferon therapy. OBJECTIVE: To analyze the frequency of positivity to autoantibodies in multiple scl...