supported by the National Natural Science Foundation of China (81790624 and C-0052);Natural Science Foundation of Hubei Province (2020CFA016)。
Myocarditis is an inflammatory cardiac disease characterized by the destruction of myocardial cells, infiltration of interstitial inflammatory cells, and fibrosis, and is becoming a major public health concern. The ae...
Idiopathic nephrotic syndrome(INS)describes a group of rare glomerular diseases characterized by massive proteinuria and hypoalbuminemia in the absence of glomerular inflammatory lesions or immunoglobulin deposits.INS...
supported by the scholarships provided by São Paulo Research Foundation(FAPESP),No.2013/02371-6(to LANM),No.2013/01604-7(to SFGZP),No.2013/14353-2(to TFCFS),No.2015/06706-8(to LANM)and No.2019/15980-7(to MBD);financial support grants No.2013/26257-8;São Paulo Research Foundation(FAPESP)and No.307269/2017-5;the National Council for Scientific and Technological Development(CNPq),to AS.
Multiple sclerosis is an autoimmune treatable but not curable disease.There are a multiplicity of medications for multiple sclerosis therapy,including a class entitled disease-modifying drugs that are mainly indicated...
Despite the advances in therapy,hepatitis B virus(HBV)and hepatitis C virus(HCV)still represent a significant global health burden,both as major causes of cirrhosis,hepatocellular carcinoma,and death worldwide.HBV is ...
Crimean-Congo hemorrhagic fever virus(CCHFV) is responsible for widespread tick-borne zoonotic viral disease CCHF in African, Middle Eastern, Asian, and European countries. CCHFV can be spread to humans through tick b...
This study was supported by the National Natural Foundation of China(81770710);Key Research and Development Plan of Zhejiang Province(2019C03028);the Major projects jointly constructed by the Zhejiang Province,and National Health Commission(WKJ-ZJ-1908).
Background Idiopathic nephrotic syndrome is a common form of glomerular nephropathy in children,with an incidence rate of 1.15-16.9/100,000 depending on different nationalities and ethnicities.The etiological factors ...
Although 80%of individuals infected with the severe acute respiratory syndromecoronavirus 2(SARS-CoV-2)recover without antiviral treatments,the other 20%progress to severe forms of pulmonary disease,suggesting that th...
supported by grants from the Emergency Prevention and Control of COVID-19 Project of Henan Province(grant no.201100310900);the 2020 Science and Technology Project of Henan Province(grant no.202102310039);the National Natural Science Foundation of China(grant nos.91942314,U1804281,81602024);the State’s Key Project of Research and Development Plan(grant nos.2018YFC1313400,2016YFC1303500)。
The recent novel coronavirus disease(COVID-19)outbreak,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is seeing a rapid increase in infected patients worldwide.The host immune response to SARS-C...
Supported by National Natural Science Foundation of China(No.81200719);China Postdoctoral Science Foundation(No.2013M543579; No.2014T71013);Key Specialized Projects in Nanjing(No.SZDZK2016008)
Currently, thyroid-associated ophthalmopathy (TAO) lacks effective treatment due to our lack of clarity in its immunopathogenesis. Orbital fibroblasts play a key role in altering inflammation and immune response in TA...
supported by a grant from the National Natural Science Foundation of China(81170375)
BACKGROUND: The integrative analysis of microRNA and mRNA expression profiles can elucidate microRNA-targeted gene function. We used this technique to elucidate insights into the immunological pathology of non-alcoho...