IMMUNOMODULATORY

作品数：145被引量：596H指数：14
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相关领域：医药卫生更多>>
相关作者：王景昌吴涛欧剑锋白海路继红更多>>
相关机构：华中科技大学兰州军区兰州总医院郑州大学第一附属医院苏州大学更多>>
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Potential benefits of Nigella Sativa(black seeds)in the management of“Chandipura virus infection”–an insight
《Food and Health》2025年第2期3-14,共12页Naina Mohamed Pakkir Maideen 
The Chandipura vesiculovirus(CHPV),a single-stranded,negative sense RNA arbovirus with five structural proteins-the G,N,M,P,and L proteins-is the source of Chandipura virus infection.Children between the ages of 9 mon...
关键词：Chandipura virus ENCEPHALITIS Nigella Sativa black seeds black cumin seeds THYMOQUINONE antiviral anti-inflammatory antioxidant IMMUNOMODULATORY 
Immunomodulatory behavior of CircRNAs in tumor microenvironment
《Oncology Research》2025年第5期1105-1119,共15页HAISU LIANG WEI YAN ZHI LIU YUNBO HE JIAO HU ZHIWEI SHU HUIHUANG LI BELAYDI OTHMANE WENBIAO REN CHAO QUAN DONGXU QIU MINFENG CHEN WEI XIONG BINGNAN ZHANG PEIHUA LIU 
supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).
Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...
关键词：Circular RNA(circRNA) Immune response Metabolic reprogramming TUMOR Tumor microenvironment(TME) 
Molecular mechanism of exopolysaccharide biosynthesis regulated by wze and wzd genes on the immunomodulatory effects of probiotic Lacticaseibacillus paracasei S-NB
《Food Science and Human Wellness》2025年第1期293-306,共14页Luyao Xiao Qian Yang Changliang Zhang Kai Ma Xiaogan Zhao Xin Rui Wei Li 
co-financed by the International Science&Technology Cooperation Program of Hainan Province(GHYF2023009);Jiangsu Provincial Key Research and Development Program(BE2022325);Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX23_0777);Qing Lan Project of Jiangsu Province and Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
The surface macromolecules of probiotic bacteria play crucial roles in modulating immune responses in the host.Exopolysaccharide(EPS)from lactic acid bacteria(LAB)have been widely reported to exhibit immunomodulatory ...
关键词：Lacticaseibacillus paracasei Exopolysaccharide(EPS) BIOSYNTHESIS IMMUNOMODULATORY 
Immunomodulatory hydrogel neutralizes tumor acidity to augment immune responses for the prevention of post-surgical recurrence of melanoma
《Science China Materials》2025年第1期270-279,共10页Zhiyuan Quan Linghui Chen Beibei Chen Kangli Guo Pengfei Tian Haobo Pan Yang Li Nana Zhao Fu-Jian Xu 
National Key Research and Development Program of China (2021YFC2400500);National Natural Science Foundation of China (52173271, 52361165659, and 52221006);Beijing Outstanding Young Scientist Program(BJJWZYJH01201910010024)。
Post-resection recurrence remains a severe problem in melanoma treatment.New therapeutic strategies,such as chemodynamic therapy(CDT),exhibit high specificity and responsiveness,demonstrating potential to elicit antit...
关键词：borosilicate glasses tumor microenvironment chemodynamic therapy tumor acidity melanoma immunotherapy 
Extended protective effects of three dimensional cultured human mesenchymal stromal cells in a neuroinflammation model
《World Journal of Stem Cells》2025年第1期53-65,共13页Ok-Hyeon Kim Hana Kang Eun Seo Chang Younghyun Lim Young-Jin Seo Hyun Jung Lee 
Supported by National Research Foundation of Korea,No.RS-2024-00409554,No.2023R1A2C2006894,and No.2021R1A6A3A01088243.
BACKGROUND Human mesenchymal stromal cells(MSCs)possess regenerative potential due to pluripotency and paracrine functions.However,their stemness and immunomod-ulatory capabilities are sub-optimal in conventional two-...
关键词：Mesenchymal stromal cells Three-dimensional culture Immunomodulatory function NEUROINFLAMMATION Cell therapy 
Role of immunomodulatory probiotics in alleviating bacterial diarrhea in piglets:a systematic review
《Journal of Animal Science and Biotechnology》2024年第6期2175-2199,共25页Sudeb Saha Fu Namai Keita Nishiyama Julio Villena Haruki Kitazawa 
supported by Grants-in-Aid for Scientific Research(A)(19H00965,23H00354 HK);Grant-in-Aid for Scientific Research(B)(23H02358,KN);Grant-in-Aid for Research Activity Start-up(23K19327,FN);Challenging Research(Exploratory,23K18072,HK);JSPS Fellows(22F22080,HK)from the Japan Society for the Promotion of Science(JSPS);supported by the Research Program on Development of Innovative Technology Grants(JPJ007097)from the Project of the Bio-Oriented Technology Research Advancement Institution(BRAIN)and by the Japan Racing Association to HK;supported by the JSPS Core-to-Core Program,A.Advanced Research Networks,titled Establishment of the International Agricultural Immunology Research Core for Quantum Improvement in Food Safety。
Diarrhea is a common enteric disease in piglets that leads to high mortality and economic losses in swine production worldwide.Antibiotics are commonly used to prevent or treat diarrhea in piglets.However,irrational a...
关键词：CLOSTRIDIUM DIARRHEA E.COLI Immunomodulatory effect PIGLETS PROBIOTICS 
Efficient suppression of oral squamous cell carcinoma through spatial dimension conversion drug delivery systems-enabled immunomodulatory-photodynamic therapy
《Chinese Chemical Letters》2024年第12期239-244,共6页Jiechen Liu Xiaoguang Li Ruiyang Xia Yuqi Wang Fenghe Zhang Yongzhi Pang Qing Li 
supported by the National Natural Science Foundation of China(No.81802709);the Shandong Provincial Natural Science Foundation,China(Nos.ZR2023MH230,ZR2023MH096);the Shandong Provincial Postdoctoral Innovative Talents Funded Scheme;Plan of Young Scholars of Shandong University。
Patients with oral squamous cell carcinoma(OSCC)encounter challenges in achieving efficient antitumor immunity,primarily due to the inherent pathophysiological characteristics of solid tumors affecting drug accumulati...
关键词：OSCC IMMUNOTHERAPY PDT SDDDSs Downsize 
Next-generation aluminum adjuvants:Immunomodulatory layered double hydroxide NanoAlum reengineered from first-line drugs
《Acta Pharmaceutica Sinica B》2024年第11期4665-4682,共18页Zhenwei Su Hamz oucetta Jiahui Shao Jinling Huang Ran Wang Aining Shen Wei He Zhi Ping Xu Lingxiao Zhang 
European Union's Research and Innovation Program under the Marie Skłodowska-Curie grant agreement(No.101064861);National Natural Science Foundation of China(Nos.32101123,82073782 and 82241002);Guangdong Basic and Applied Basic Research Foundation(No.2022A1515110109,China);Natural Science Foundation of Ningbo(No.2022J273,China).
Aluminum adjuvants(Alum),approved by the US Food and Drug Administration,have been extensively used in vaccines containing recombinant antigens,subunits of pathogens,or toxins for almost a century.While Alums typicall...
关键词：Aluminum adjuvants Layered double hydroxide Nano-aluminum adjuvants Cancer immunotherapy T cell immunity IMMUNOMODULATORY Immunogenic cell death Metal cations 
Nanomaterial‑Based Repurposing of Macrophage Metabolism and Its Applications
《Nano-Micro Letters》2024年第11期494-528,共35页Tingting Meng Danfeng He Zhuolei Han Rong Shi Yuhan Wang Bibo Ren Cheng Zhang Zhengwei Mao Gaoxing Luo Jun Den 
financially supported by the National Natural Science Foundation of China(Nos.92168106 and 82222039).
Macrophage immunotherapy represents an emerging therapeutic approach aimed at modulating the immune response to alleviate disease symptoms.Nanomaterials(NMs)have been engineered to monitor macrophage metabolism,enabli...
关键词：Immunomodulatory nanomaterial Macrophage polarization Macrophage metabolic reprogramming Immune engineering 
Interfacial delivery of carbon monoxide via smart titanium implant coating for enhanced soft tissue integration with switchable antibacterial and immunomodulatory properties被引量：1
《Bioactive Materials》2024年第10期318-333,共16页Minghao Zhou Gangfeng Li Jingwei Yu Qian Zhou Kun Wang Jiaxin Kang Tengjiao Wang Peng Li Hongbo Wei 
support from the Natural Science Foundation of China(52073224 and 52073230);the Shaanxi Provincial Science Fund for Distinguished Young Scholars(2023-JC-JQ-32);Key Research and Development Program of Shaanxi(2024SFYBXM-438 and 2022SF-165);Natural Science Foundation of Chongqing(CSTB2023NSCQ-MSX0225).
Soft tissue integration around titanium(Ti)implants is weaker than that around natural teeth,compromising long-term success of Ti implants.Carbon monoxide(CO)possesses distinctive therapeutic properties,rendering it a...
关键词：Gastrotransmitters Soft tissue integration Immune microenvironment Ti implants ANTIBACTERIAL 
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