SALMETEROL

作品数：18被引量：54H指数：4
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相关作者：孙滨倪殿涛丁黎更多>>
相关机构：第四军医大学西京医院新疆维吾尔自治区人民医院中国药科大学更多>>
相关期刊：《Chinese Medical Journal》《国外新药介绍》《Chemical Research in Chinese Universities》《广东药科大学学报》更多>>
相关基金：国家重点基础研究发展计划国家自然科学基金博士科研启动基金国家科技支撑计划更多>>
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Efficacy ofβ2-adrenergic receptor agonist combined with corticosteroid in the treatment of children with cough variant asthma被引量：3
《World Journal of Clinical Cases》2023年第31期7610-7618,共9页Jun-Yi Cao Ying-Chun Wang Xiao-Xia Deng 
BACKGROUND Cough variant asthma(CVA)is one of the most common respiratory diseases in children,which has a serious impact on the quality of life and daily activities of children.For severe CVA,immunomodulatory drugs a...
关键词：SALMETEROL BUDESONIDE Cough variant asthma PEDIATRICS Efficacy analysis 
Clinical Effect of Salmeterol and Fluticasone Powder Inhalation Combined with Aminophylline Injection in the Treatment of Senile Bronchial Asthma
《外文科技期刊数据库(文摘版)医药卫生》2022年第6期090-094,共5页CHENLiling 
Objective: to analyze the therapeutic effect of salmeterol fluticasone powder inhalation combined with aminophylline injection on senile bronchial asthma. Methods: 62 elderly patients with bronchial asthma in our hosp...
关键词：salmeterol fluticasone powder inhalation aminophylline injection old age bronchial asthma lung function index the effective rate of treatment inflammatory factor index 
Efficacy and safety of salmeterol/fluticasone compared with montelukast alone (or add-on therapy to fluticasone) in the treatment of bronchial asthma in children and adolescents: a systematic review and meta-analysis被引量：27
《Chinese Medical Journal》2021年第24期2954-2961,共8页Xiao-Jian Zhou Zhen Qin Jiao Lu Jian-Guo Hong 
Background:Despite the recommendation of inhaled corticosteroids(ICSs)plus long-acting beta 2-agonist(LABA)and leukotriene receptor antagonist(LTRA)or ICS/LTRA as stepwise approaches in asthmatic children,there is a l...
关键词：Bronchial asthma Fluticasone/salmeterol MONTELUKAST Systematic review Pediatric 
Discovery of β-arrestin-biased β2-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives被引量：2
《Acta Pharmacologica Sinica》2019年第8期1095-1105,共11页Yiu-Ho Woo Xin-yue Ge Li Pan Gang Xing Yong-mei Mo Rui-juan Xing Xiao-ran Li Yu-yang Zhang Irving W. Wainer Mao-sheng Cheng Rui-ping Xiao 
We thank Dr. Joseph Kozocas from SRI international, California, USA for providing (R,/T)-FEN and (&R1-MNF for the analysis and Dr. Wei Liang and his team from WuXi AppTec, Shanghai, China for technical assistance in the cAMP assay. This work was supported by the Ministry of Science and Technology of the People's Republic of China under the National Key Research and Development Program of China [grant number 2018YFA0507603 (to R-PX)];the National Science and Technology Major Project [grant numbers 2013ZX09507001-001002 (to AY-HW), 2013ZX09301305-001 (to LP), 2013ZX09508104 (to R-PX), 2018ZX09739009 (to M-SC)];the National Basic Research Program [grant number 2012CB518000 (to R-PX)];the National Natural Science Foundation of China [grant numbers 81673355 (to AY-HW), 81872752 (to MSC), 31521062, 81630008, 81790621 (to R-PX)];Beijing Municipal Science & Technology Commission [grant number Z171100000417006 (to R-PX)], and the intramural research program of the NIH, USA (to IWW).
β-Arrestins are a small family of proteins important for signal transduction at G protein-coupled receptors (GPCRs).β-Arrestins are involved in the desensitization of GPCRs. Recently, biased ligands possessing diffe...
关键词：β2-adrenoceptor AGONISTS cAMP Β-ARRESTIN biased AGONISM FENOTEROL SALMETEROL heart failure asthma 
美国FDA批准哮喘药Advair Diskus首个仿制药上市
《广东药科大学学报》2019年第1期96-96,共1页夏训明(编译) 
葛兰素史克(Glaxo SmithKline)公司的哮喘/慢性阻塞性肺病治疗药物Advair Diskus的专利到期,该药是复方药,有效成分为丙酸氟替卡松(fluticasone propionate,CAS登记号为80474-14-2)和沙美特罗(salmeterol,CAS登记号为89365-50-4),剂型...
关键词：美国FDA 哮喘药 仿制药 FDA批准 上市 SALMETEROL 慢性阻塞性肺病 pulmonary 
Development and validation of a novel UPLC-MS/MS method for the simultaneous determination of fluticasone propionate and salmeterol in human plasma
《Journal of Chinese Pharmaceutical Sciences》2017年第4期271-283,共13页高宇雄 丁黎 梁文忠 蒋华芳 
Combined administration of fluticasone propionate and salmeterol xinofoate has been widely used for the treatment of asthma in recent decades. In this investigation, we developed and validated a novel and sensitive ul...
关键词：Fluticasone propionate Salmeterol xinofoate UPLC-MS/MS Human plasma Chinese subjects 
Stereoselective Synthesis of （R）-Salmeterol via Asymmetric Cyanohydrin Reaction
《Chemical Research in Chinese Universities》2014年第5期770-773,共4页LI Wei HUANG Hai JIN Xiaodong LIU Yujian XU Chaohang ZHU Hongjun 
The authors described a short and highly enantioselective route to （R）-salmeterol involving asymmetric synthesis of cyanohydrin followed by nucleophilic substitution with 6-（4-phenylbutoxy） hexyl methanesulfonate.
关键词：Asymmetric synthesis CATALYSIS CYANOHYDRIN ETHANOLAMINE METHANESULFONATE 
Budesonide/formoterol maintenance and reliever therapy in Chinese patients with asthma被引量：8
《Chinese Medical Journal》2012年第17期2994-3001,共8页LIN Jiang-tao CHEN Ping ZHOU Xin SUN Tie-ying XIE Can-mao XIU Qing-yu YAO Wan-zhen YANG Lan YIN Kai-sheng ZHANG Yong-ming 
Background Many studies have shown the superior efficacy of budesonide （BUD）/formoterol （FORM） maintenance and reliever therapy, but still lack evidence of its efficacy in Chinese asthma patients in a relative lar...
关键词：ASTHMA BUDESONIDE/FORMOTEROL EXACERBATION salmeterol/iquticasone 
Salmeterol attenuates the inflammatory response in asthma and decreases the pro-inflammatory cytokine secretion of dendritic cells被引量：9
《Cellular & Molecular Immunology》2012年第3期267-275,共9页Zhenli Hu Ruohua Chen Zhijian Cai Lei Yu Yang Fei Lixia Weng Jinghan Wang Xiahui Ge Tianyi Zhu Jianli Wang Chong Bai 
Salmeterol is a long-acting β2-agonist that activates adenylate cyclase, causing long-lasting bronchodilation and has been used for many years to control asthma. However, little information is available about the imm...
关键词：ASTHMA dendritic cells pro-inflammatory cytokines SALMETEROL 
FDA建议明确标示儿童使用沙美特罗的潜在危险
《药学进展》2008年第4期F0003-F0003,共1页孙大柠 
关键词：沙美特罗 SALMETEROL 哮喘 儿童 
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