ICOTINIB

作品数:17被引量:72H指数:5
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相关领域:医药卫生更多>>
相关作者:赵晶晶李亚楠彭冲刘魏王芹芳更多>>
相关机构:温州医科大学北京交通大学青岛市肿瘤医院华北制药集团新药研究开发有限责任公司更多>>
相关期刊:《药学进展》《Asian Journal of Social Pharmacy》《World Journal of Gastroenterology》《Oncology and Translational Medicine》更多>>
相关基金:国家自然科学基金更多>>
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Sequential chemotherapy and icotinib as first-line treatment for advanced epidermal growth factor receptor-mutated non-small cell lung cancer被引量:2
《World Journal of Clinical Cases》2022年第18期6069-6081,共13页Sheng-Jie Sun Jin-Di Han Wei Liu Zhi-Yong Wu Xiao Zhao Xiang Yan Shun-Chang Jiao Jian Fang 
BACKGROUND Icotinib could have potential effect and tolerability when used sequentially with chemotherapy for advanced epidermal growth factor receptor(EGFR)-mutated non-small cell lung cancer(NSCLC).AIM To evaluate t...
关键词:Advanced stage CHEMOTHERAPY Epidermal growth factor receptor mutation First-line treatment ICOTINIB 
Efficacy of the apatinib and icotinib combination therapy in the treatment of icotinib-resistant advanced lung adenocarcinoma:A case study
《TMR Cancer》2021年第5期4-7,共4页Ling-Juan Gao 
A patient with advanced lung adenocarcinoma who was unable to tolerate chemotherapy was controlled after combined treatment with apatinib.This case provides a basis for the treatment of this disease using this method....
关键词:Apatinib EGFR-TKI Lcotinib hydrochloride tablets agedness lung adenocarcinoma 
Lung adenocarcinoma harboring rare epidermal growth factor receptor L858R and V834L mutations treated with icotinib:A case report
《World Journal of Clinical Cases》2020年第17期3841-3846,共6页Shu-Sen Zhai Hui Yu Tian-Tian Gu Yan-Xia Li Yan Lei Hai-Yan Zhang Tong-Huan Zhen Yun-Ge Gao 
BACKGROUND Epidermal growth factor receptor(EGFR)tyrosine-kinase inhibitors are widely used for the treatment of non-small-cell lung cancer with EGFR mutations.However,patients with rare,even compound EGFR mutations h...
关键词:Icotinib hydrochloride Epidermal growth factor receptor L858R/V834L Nonsmall cell lung cancer Stable disease Case report 
Durable response to pulsatile icotinib for central nervous system metastases from EGFR-mutated non-small cell lung cancer: A case report
《World Journal of Clinical Cases》2020年第2期370-376,共7页Hui-Ying Li Yu Xie Ting-Ting Yu Yong-Juan Lin Zhen-Yu Yin 
Supported by the Key Project of Nanjing Health Bureau,No.ZKX16031;the Healthcare Project of Nanjing Science and Technology Committee,No.201715020;the Medical Key Science and Technology Development Project of Nanjing,No.ZKX18014;the Cadre Health Care Project of Jiangsu Province,No.BJ18006;the Cancer Research Funding of CSCO-Hausen,No.Y-HS2019-5
BACKGROUND Central nervous system(CNS) metastases are a catastrophic complication of nonsmall cell lung cancer(NSCLC), including brain and leptomeningeal carcinomatosis, and are always accompanied by a poor prognosis....
关键词:Non-small cell lung cancer Central nervous system metastases EGFR mutation Pulsatile icotinib Case report 
Pharmacoeconomic Study on the Treatment of Terminal Non-small Cell Lung Cancer with Icotinib and Pemetrexed Combined with Cisplatin
《Asian Journal of Social Pharmacy》2019年第4期204-208,共5页Chai Dongye Zhang Fang 
Objective To provide theoretical basis for clinical treatment of patients with terminal non-small cell lung cancer through the analysis of the cost and adverse reactions of the joint treatment of icotinib and pemetrex...
关键词:NON-SMALL cell lung cancer(NSCLC) ICOTINIB PEMETREXED CISPLATIN 
Bevacizumab Combined with Icotinib Overcomes Osimertinib Resistance in a Patient of Non-Small Cell Lung Cancer被引量:2
《Chinese Medical Sciences Journal》2019年第4期292-296,共5页张玲 孙雷 穆晓燕 季有信 
A 61-year-old Chinese woman was diagnosed as primary pulmonary adenocarcinoma of left superior lobe with epidermal growth factor receptor(EGFR)19 del mutation positive.Treatment with icotinib was given,but her disease...
关键词:Epidermal growth factor receptor-tyrosine kinase inhibitor resistant mutation nonsmall cell lung cancer BEVACIZUMAB 
Icotinib plus osimertinib overcome epidermal growth factor receptor 19del/T790 M/C797S/V834L quadruplet resistance mutation in a patient with non-small cell lung cancer被引量:2
《Chinese Medical Journal》2019年第9期1115-1116,共2页Chao Zhu Yun-Hong You Ke-Ke Nie You-Xin Ji 
To the Editor:A 66-year-old woman presented with a severe cough and was admitted into hospital in April 2014.Positron emission tomography/computed tomography (PET/CT) scan showed a 2.0 cm×2.0 cm node located on the l...
关键词:EDITOR WOMAN LUNG 
Achievable complete remission of advanced non-small-cell lung cancer: Case report and review of the literature被引量:5
《World Journal of Clinical Cases》2018年第7期150-155,共6页Ning-Ning Yang Fei Xiong Qing He Yong-Song Guan 
Surgery is the first choice of treatment for patients with non-small-cell lung cancer(NSCLC), but few patients can be treated surgically because of either advanced disease or poor pulmonary function. Other therapies i...
关键词:TYROSINE kinase inhibitor BRONCHIAL artery infusion ICOTINIB HYDROCHLORIDE EPIDERMAL growth factor receptor ADVANCED non-small-cell lung cancer 
Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1被引量:7
《Acta Pharmaceutica Sinica B》2017年第6期657-664,共8页Xuewei Cheng Xia Lv Hengyan Qu Dandan Li Mengmeng Hu Wenzhi Guo Guangbo Ge Ruihua Dong 
financially supported by National Natural Science Foundation of China (81403002, 81473181, and 81573501);the First Affiliated Hospital of Zhengzhou University (201613);Innovative Entrepreneurship Program of High-Level Talents in Dalian (2016RQ025)
UDP-glucuronosyltransferase 1A1(UGT1A1) plays a key role in detoxification of many potentially harmful compounds and drugs. UGT1A1 inhibition may bring risks of drug–drug interactions(DDIs), hyperbilirubinemia and dr...
关键词:ICOTINIB ERLOTINIB UGT1A1 Inhibitory effects Drug–drug interactions(DDIs) 
Icotinib, an EGFR-TKI, for the treatment of brain metastases in non-small cell lung cancer:a retrospective study
《Oncology and Translational Medicine》2016年第6期268-274,共7页Qunhui Wang Hua Zheng Ying Hu Baohua Lu Fanbin Hu Hongmei Zhang Baolan Li 
Objective Treatment of brain metastases from non-small cell lung cancer(NSCLC) is a challenge because of the poor prognosis. Icotinib is a new type of oral epidermal growth factor receptor(EGFR) tyrosine kinase inhibi...
关键词:non-small cell lung cancer(NSCLC) brain metastases ICOTINIB epidermal growth factor receptor(EGFR) 
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