GRANISETRON

作品数:12被引量:18H指数:2
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相关领域:医药卫生更多>>
相关作者:周中梅汪丽川徐光川刘茂珍朱玲更多>>
相关机构:中山医科大学肿瘤医院华西医科大学更多>>
相关期刊:《当代医学》《World Journal of Gastroenterology》《Neural Regeneration Research》《癌症》更多>>
相关基金:国家自然科学基金更多>>
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5-Hydroxytryptamine:a potential therapeutic target in amyotrophic lateral sclerosis被引量:2
《Neural Regeneration Research》2023年第9期2047-2055,共9页Shi-Shi Jiang Meng-Ni Gong Wei Rao Wen Chai Wen-Zhi Chen Xiong Zhang Hong-Bing Nie Ren-Shi Xu 
supported by the National Natural Science Foundation of China,Nos.30560042,81160161,81360198;82160255;Education Department of Jiangxi Province,Nos.GJJ13198 and GJJ170021;Jiangxi Provincial Department of Science and Technology,Nos.20142BBG70062,20171 BAB215022,20192BAB205043;Health and Family Planning Commission of Jiangxi Province,No.20181019 (all to RSX)。
Previous studies have indicated that the pathogenesis of amyotrophic lateral sclerosis(ALS) is closely linked to 5-hydroxytryptamine(5-HT).To investigate this further,we administered 5-HT receptor antagonists to SOD1*...
关键词:5-HYDROXYTRYPTAMINE amyotrophic lateral sclerosis ASTROCYTES GRANISETRON MICROGLIA neuron piboserod RITANSERIN SOD1-G93A TAR DNA-binding protein 43 
Theoretical Investigation of Adsorption Effects of Granisetron Anticancer Drug over BN(7,7-7) Nanotube as a Factor of Drug Delivery: a DFT Study
《Chinese Journal of Structural Chemistry》2019年第9期1421-1431,共11页ZIBA Tavakoli 
supported by the Islamic Azad University of Genaveh
In the present work, the interaction between drug Granisetron(GRS) and BN(7,7-7) nanotube by density functional theory(DFT) calculations in the solvent water has been investigated. The non-bonded interaction effects o...
关键词:GRANISETRON BN(7 7-7) NANOTUBE DFT adsorption NBO 
Carbon monoxide contributes to the constipating effects of granisetron in rat colon被引量:1
《World Journal of Gastroenterology》2016年第42期9333-9345,共13页Carmela Nacci Margherita Fanelli Maria Assunta Potenza Valentina Leo Monica Montagnani Maria Antonietta De Salvia 
Supported by Universitàdegli Studi di Bari,protocol No.10110 tit-VIII/2
AIM To investigate the mechanisms underlying the potential contribution of the heme oxygenase/carbon monoxide(HO/CO) pathway in the constipating effects of granisetron. METHODS For in vivo studies, gastrointestinal mo...
关键词:GRANISETRON Carbon monoxide Heme oxygenase COLON CONTRACTION Neurogenic response Myogenic response 
Cathodic adsorptive stripping voltammetry of an anti-emetic agent Granisetron in pharmaceutical formulation and biological matrix
《Journal of Pharmaceutical Analysis》2012年第6期443-449,共7页Rajeev Jain Ramkishor Sharma 
Granisetron showed one well-defined reduction peak at Hanging Mercury Drop Electrode (HMDE) in the potential range from -1.3 to -1.5 V due to reduction of C=N bond. Solid-phase extraction technique was employed for ...
关键词:GRANISETRON Human plasma Solid-phase extraction Pharmaceuticalformulation VOLTAMMETRY Hanging mercury dropelectrode 
Granisetron Transdermal Patch for Treatment of Nausea in Patients Undergoing Cisplatin Based Chemotherapy for Cervical Cancer
《Journal of Cancer Therapy》2012年第6期1159-1163,共5页Helen Dunnington Rodney Hunter Michael Frumovitz Judith Smith 
Objective: The purpose of this study was to define the incidence of chemotherapy-induced nausea and vomiting (CINV) in newly diagnosed cervical cancer patients receiving cisplatin and radiation treatment;and to determ...
关键词:GRANISETRON NAUSEA VOMITING CISPLATIN Radiation 
Effect of granisetron in preventing vomiting after chemiotherapy
《中国临床康复》2003年第7期1211-1211,共1页王中华 陈冬波 
关键词:格拉司琼 预防 化学疗法 呕吐 
CLINICAL COMPARISON OF THE SELECTIVE SEROTONIN_3 ANTAGONISTS RAMOSETRON AND GRANISETRON IN TREATING ACUTE CHEMOTHERAPY-INDUCED EMESIS,NAUSEA AND ANOREXIA被引量:2
《Chinese Medical Sciences Journal》2002年第3期168-172,共5页冯奉仪 张频 何友兼 李宇红 周美珍 陈刚 李琳 
Feng Fengyi , Zhang Pin , He Youjian 1, Li Yuhong1 , Zhou Meizhen2 , Chen Gang2 and Li Lin2 The Cancer Hospital of the CAMS & PUMC, Beijing 1000211 The Cancer Hospital of Sun Yat Sen University of Medical Sciences, G...
关键词:HT3 antagonist ramosetron granisetronObjective. The efficacies of the selective 5  hydroxytryptamine3 (5  HT3) antagonists——ramosetron (0.3 mg) and granisetron (3 mg) in treating acute chemotherapy  induced digestive system dysfunction were 
GRANISETRON COMPARED WITH ONDANSETRON PLUS DEXAMETHASONE IN THE PREVENTION OF NAUSEA AND VOMITING INDUCED BY A INTENSELY EMETOGENIC CHEMOTHERAPY REGIMEN:A RANDOMIZED CROSS-OVER STUDY
《Chinese Journal of Cancer Research》1996年第1期60-63,共4页于丁 邓华邦 范玉华 付小玉 柯玉华 胡艳萍 周运华 杨玲 
Fifty-two patients with chemotherapy comprise cisplatin, adriamycin and dacarbazine underwent antiemetic therapy form September 1994 to June 1995. The chemotherapy regimens include CAP-VDS, ACO, EP,CHOP, AMF and MFP. ...
关键词:ANTIEMETICS CHEMOTHERAPY Vomiting granisetron Ondansetrou Dexamethasone. 
Granisetron——一种防治癌症化疗所致呕吐的新药被引量:1
《四川生理科学杂志》1996年第1期33-35,共3页朱玲 
Granisetron为一种新型镇吐药,是5-HT_3受体选择性竞争拮抗剂,能有效地防治癌症化疗所致的恶心、呕吐,对放疗引起的呕吐也有效。Granisetron与其它镇吐药相比,疗效确实,病人容易接受,极具应用潜力,最近已为美国FDA批准应用于临床。
关键词:GRANISETRON 化疗所致呕吐 防治癌症 受体拮抗剂 延迟呕吐 锥体外系反应 镇吐药 灭吐灵 癌症化疗 临床试验 
联合使用地塞米松与granisetron预防化疗时引起的恶心呕吐效果良好
《当代医学》1995年第1期55-55,共1页张竟春 
1992年12月至1994年1月连续入院的428名首次接受中度致吐化疗的病人被纳入一个双盲、随机与多中心的关于三种抗呕吐治疗方案的效用与毒性的评价研究中。化疗方案为:环磷酰胺600~1000mg/m^2,阿霉素≥50mg/m^2,表柔比星≥75mg/m^2或者卡...
关键词:地塞米松 联合使用 预防化疗 评价研究 治疗方案 表柔比星 单独作用 阿霉素 静脉注射 恶心呕吐 
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