MONOPHOSPHATE

作品数：89被引量：261H指数：8
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Endogenous nucleotide as drug carrier:base-paired guanosine-5’-monophosphate:pemetrexed vesicles with enhanced anticancer capability
《Science China Chemistry》2020年第2期244-253,共10页Lei Xu Chunyang Yu Dali Wang Ji Pang Leilei Shi Yue Su Lidong Gong Deyue Yan Xinyuan Zhu 
supported by the Shanghai Municipal Government(18JC1410800);the National Natural Science Foundation of China(51690151,21774077)
Endogenous substance such as nucleotide as a drug carrier has been proposed as a novel drug delivery system.The nucleotide guanosine-5’-monophosphate(GMP) is used to transport an anticancer drug pemetrexed disodium h...
关键词：endogenous carrier hydrogen bonding NANOVESICLES drug delivery cancer therapy 
Fast electron transfer repair of oxidizing OH adduct of dGMP by chlorogenic acid
《Science China Chemistry》1998年第5期556-560,共5页马建华 钱素平 林维真 姚思德 
ProjectsupportedbytheNationalNaturalScienceFoundationofChina (GrantNo .39130 0 5 0 )
Pulse radiolysis of chlorogenic acid (CGA) as well as CGA and 2′\|deoxyguanosine\|5′\|monophosphate (dGMP) has been carried out in aqueous solution using pulse radiolytic technique. From detailed kinetic analyses, t...
关键词：pulse RADIOLYSIS chlorogenic acid 2′\|deoxyguanosine\|5′\|monophosphate. 
THE EFFECTS OF PERFUSION OF LATERAL VENTRICLE WITH CaCl_2 ON THE FEBRILE RESPONSE AND cAMP CONTENT IN PLASMA AND CEREBROSPINAL FLUID DURING LP-INDUCED FEVER被引量：1
《Science China Chemistry》1991年第3期317-326,共10页张怡 李楚杰 
Artificial cerebrospinal fluid (c.s.f.) containing 40 mmol/L excess calcium was perfus-ed through the lateral ventricles of New Zealand white rabbits in order to reduce the Na^+/Ca^(++) ratio in the brain and the effe...
关键词：ADENOSINE cyclic MONOPHOSPHATE sodium calcium PYROGEN FEVER 
EFFECTS OF SODIUM SALICYLATE ON THE FEBRILE RESPONSE AND INCREASED LEVELS OF CYCLIC AMP IN CEREBRO-SPINAL FLUID DURING ENDOGENOUS PYROGEN-INDUCED FEVER IN RABBITS
《Science China Chemistry》1989年第10期1215-1223,共9页刘晓莹 李楚杰 
To further evaluate the causality between endogenous pyrogen (EP)-induced fever andcyclic adenosine- 3’, 5’- monophosphate (cyclic AMP) level. the effects of sodium salicylate(SS) on the febrile response and increas...
关键词：sodium SALICYLATE PYROGEN FEVER ADENOSINE cyclic MONOPHOSPHATE 
STUDY ON THE MECHANISM OF INTERFERON ACTION (Ⅺ)——EFFECT OF pppA2'p5'A2'p5'A ON THE LEVEL OF cAMP AND cGMP IN MACROPHAGES
《Science China Chemistry》1989年第8期970-975,共6页尹桂山 杜秀全 王桂香 王学孟 张牧霞 赵文政 陈寅 姚曼华 郑宏大 刘新垣 
the National Natural Science Foundation of China.
In this paper, the increase of cellular cAMP and cGMP levels in macrophages induced bypppA2'p5'A2'p5'A (briefly 2'-5'P_3A_3) is first reported. The optimal concentration of 2'-5'P_3A_3 for the elevation of cellular cG...
关键词：INTERFERON 2'-5'-oligoadenylate (2'-5' P_3A_3) adenosine-3' 5'-monophosphate (cAMP) guanosine-3' 5'-monophosphate (cGMP) macrophage 
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