MONOPHOSPHATE

作品数：92被引量：261H指数：8
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相关领域：医药卫生更多>>
相关作者：肖明芳应汉杰杨晓亮吕浩何明芳更多>>
相关机构：南京工业大学南京大学福建中医药大学中国人民解放军第一军医大学更多>>
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相关基金：国家自然科学基金福建省自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats
《Infectious Diseases of Poverty》2023年第3期51-66,共16页Yu Shen Bin Zheng Hao Sun Songrui Wu Jiyuan Fan Jianzu Ding Meng Gao Qingming Kong Di Lou Haojie Ding Xunhui Zhuo Shaohong Lu 
supported by the National Natural Science Foundation of China(No.81871684,No.81802037);the Provincial Key R&D program of Zhejiang Department of Science and Technology(No.2019C03057);the Zhejiang Provincial Natural Science Foundation of China(No.LY22H190003);the Zhejiang Medical and Health Science and Technology Plan(WKJ-ZJ-2203);the Central Leading Local Science and Technology Development Fund Project(2023ZY1019);the Key Discipline of Zhejiang Province in Public Health and Preventive Medicine(First Class,Category A),Hangzhou Medical College.
Background Toxoplasma gondii is an obligate intracellular apicomplexan parasite and is responsible for zoonotic toxoplasmosis.It is essential to develop an effective anti-T.gondii vaccine for the control of toxoplasmo...
关键词：Toxoplasma gondii Orotidine-5’-monophosphate decarboxylase PHOSPHORIBOSYLTRANSFERASE Live attenuated vaccine IMMUNIZATION Mouse Cat 
Orotidine Monophosphate Decarboxylase——A Fascinating Workhorse Enzyme with Therapeutic Potential被引量：2
《Journal of Genetics and Genomics》2015年第5期221-234,共14页Masahiro Fujihashi Jagjeet S.Mnpotra Ram Kumar Mishra Emil F.Pai Lakshmi P.Kotra 
partly supported by a Grant-in-Aid for Scientific Research (C) (24570130 to M.F.). E.F.P.;support through a Canada Research Chair. L.P.K.;the funding support over the years from Canadian Institutes of Health Research (MOP62704 to EFP and LPK; DDP-79122 to LPK, KCK and EFP); ISTPCanada (ICRD08-15);Ministry of Research and Innovation (Ontario, Canada) and Bio Discovery Toronto
Orotidine 5＇-monophosphate decarboxylase （ODCase） is known as one of the most proficient enzymes. The enzyme catalyzes the last reaction step of the de novo pyrimidine biosynthesis, the conversion from orotidine 5...
关键词：Pyrimidine biosynthesis Orotidine monophosphate decarboxylase Ligand-enzyme interactions Antimalarial agents 
A unique insertion of low complexity amino acid sequence underlies protein-protein interaction in human malaria parasite orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase被引量：1
《Asian Pacific Journal of Tropical Medicine》2014年第3期184-192,共9页Waranya Imprasittichai Sittiruk Roytrakul Sudaratana R.Krungkrai Jcrapan Krungkrai 
supported in part by Faculty of Graduate School(to W.L);Faculty of Medicine(contract no. RAH/54(1) to J.K.),Chulalongkorn University
Objective:To investigate the multienzyine complex formation of human malaria parasite Plasmodium falciparum[P.falciparum)orotate phosphoribosyltransferase(OPRT)and orotidine5'-monophosphate decarboxylase(OMPDC),the fi...
关键词：Malaria PLASMODIUM FALCIPARUM PYRIMIDINE biosynthesis Orotate PHOSPHORIBOSYLTRANSFERASE Orotidine 5’-monophosphate DECARBOXYLASE Multienzyme complex Proteomics 
Cloning of le-pyrG, an Orotidine-5＇-monophosphate Decarboxylase Encoding Gene from Lentinula edodes被引量：1
《食用菌学报》2009年第2期17-20,共4页BAO Dapeng FENG Aiping ZHANG Meiyan TAN Qi CHEN Mingjie NIU Liying PAN Yingjie 
关键词：食用菌 栽培技术 基因 克隆技术 
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