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Restoration of HBV-specific CD8+T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-αtherapy被引量：7: 《Signal Transduction and Targeted Therapy》2021年第12期3684-3696,共13页Dongyao Wang Binqing Fu Xiaokun Shen Chuang Guo Yanyan Liu Junfei Zhang Rui Sun Ying Ye Jiabin Li Zhigang Tian Haiming Wei; This work was supported by the Natural Science Foundation of China(Nos.81330071,31390433 and 81922028);the Fundamental Research Funds for the Central Universities(WK9110000168);the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2019442).; Patients with chronic hepatitis B(CHB)undergoing interferon(IFN)-α-based therapies often exhibit a poor HBeAg serological response.Thus,there is an unmet need for new therapies aimed at CHB.This study comprised two c...; 关键词：PATIENTS TREATMENT RESTORATION

Efficacy and safety of bimatoprost in glaucoma and ocular hypertension in non-responder patients: 《International Journal of Ophthalmology(English edition)》2017年第8期1251-1254,共4页Nicholas Brennan Mohammad H Dehabadi Sandhya Nair Aria Quartilho Catey Bunce Ian Reekie Raal Obikpo; AIM： To establish the efficacy and safety of bimatoprost 0.03% monotherapy in glaucoma and ocular hypertension （OHT） patients with inadequate intraocular pressure （lOP） on current therapy. METHODS： Pre- and pos...; 关键词：GLAUCOMA ocular hypertension BIMATOPROST LATANOPROST

Unsolved problems and future perspectives of hepatitis B virus vaccination被引量：2: 《World Journal of Gastroenterology》2015年第23期7074-7083,共10页Kazuto Tajiri Yukihiro Shimizu; Hepatitis B virus(HBV) infection is still a serious worldwide problem, and vaccination is the most effective strategy for primary prevention of the infection. Although universal vaccination may be required for total e...; 关键词：ESCAPE MUTANT IMMUNOLOGY Hepatitis Bvirus VACCINATION NON-RESPONDER Universal VACCINATION

Atrioventricular intrinsic conduction and cardiac resynchronization therapy被引量：1: 《Chinese Medical Journal》2011年第3期436-439,共4页WANG Ru-xing GUO Tao; Cardiac resynchronization therapy （CRT） is a major breakthrough in therapy for patients with advanced congestive heart failure, however, a number of key clinical research questions remain, perhaps most importantly t...; 关键词：heart failure cardiac resynchronization therapy atrioventricular intrinsic conduction NON-RESPONDER

Initial experiences of maintaining atrioventricular intrinsic conduction during cardiac resynchronization therapy in non-responders被引量：7: 《Chinese Medical Journal》2009年第20期2455-2460,共6页WANG Ru-xing GUO Tao HUA Bao-tong HAN Ming-hua ZHAO Ling YANG Jun LI Shu-min LIU Zhong-mei LUO Zhi-ling; Background Cardiac resynchronization therapy （CRT） is a major breakthrough in therapy for advanced heart failure patients; however, a number of key clinical research questions remain, perhaps most importantly the is...; 关键词：heart failure cardiac resynchronization therapy atrioventricular intrinsic conduction NON-RESPONDER

T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals被引量：1: 《World Journal of Gastroenterology》2008年第16期2529-2533,共5页Martin R Weihrauch Michael von Bergwelt-Baildon Milos Kandic Martin Weskott Winfried Klamp Joachim Rsler Joachim L Schultze; Supported by Sofia-Kovalevskaja Award of the Alexander von Humboldt Foundation (JL Schultze), No. 37888309, Koeln Fortune (MR Weihrauch); AIM: To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS: Fourty-seven health care employees were enrolled in ...; 关键词：Hepatitis B T cell NON-RESPONDER VACCINATION

Combination of pegylated interferon and lamivudine for patients with chronic hepatitis B who have failed treatment被引量：3: 《Hepatobiliary & Pancreatic Diseases International》2006年第3期374-380,共7页Shiv K.Sarin Manoj Kumar Syed Hissar Barjesh C.Sharma; BACKGROUND: Treatment of chronic hepatitis B (CHB) alone with interferon or lamivudine alone or in combination is effective in only a small proportion of patients. Treatment of patients in whom antiviral therapy fails...; 关键词：chronic hepatitis B pegylated interferon LAMIVUDINE NON-RESPONDER

INTRAMUSCULAR VERSUS INTRADERMAL HEPATITIS B REVACCINATIONIN HEALTHY NON-RESPONDER CHILDREN: A 5-YEAR PROSPECTIVE RANDOMIZED STUDY: 《Journal of Pharmaceutical Analysis》2005年第1期40-44,共5页庄贵华颜虹王学良吴谦王丽荣高海燕; ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina(No.30271143).; Objective With the same times of injection to compare low-dose intradermal regimen with routine-dose intramuscular inoculation in revaccination of non-responders to hepatitis B vaccine. Methods 40 healthy non-responde...; 关键词：hepatitis B vaccine NON-RESPONDER REVACCINATION

Effect of interferon and ribavirin combined with amantadine in interferon and ribavirin non-responder patients with chronic hepatitis C (genotype 1)被引量：1: 《World Journal of Gastroenterology》2005年第4期580-583,共4页Dilek Oguz Bahattin Cicek Levent Filik Bulent Odemis Mesut Kilic Engin Altintas Neslihan Zengin Emin Altiparmak; AIM: To evaluate the efficacy of amantadine plus interferonalpha and ribavirin in non-responder patients with chronic hepatitis C.METHODS: Twenty-six non-responder patients received the regimen of IFN-α-2a at a dose ...; 关键词：Chronic hepatitis C IFN-α-2a RIBAVIRIN

Long-term alpha interferon and lamivudine combination therapy in non-responder patients with anti-HBe-positive chronic hepatitis B:Results of an open,controlled trial被引量：10: 《World Journal of Gastroenterology》2003年第7期1491-1495,共5页M. Francesca Jaboli Carlo Fabbri Stefania Liva Francesco Azzaroli Giovanni Nigro Silvia Giovanelli Francesco Ferrara Anna Miracolo Sabrina Marchetto Marco Montagnani Antonio Colecchia Davide Festi Letizia Bacchi Reggiani Enrico Roda Giuseppe Mazzella; AIM: To investigate the safety and efficacy of long-term combination therapy with alpha interferon and lamivudine in non-responsive patients with anti-HBe-positive chronic hepatitis B.METHODS: 34 patients received com...; 关键词：ADULT Antiviral Agents DOSAGE Drug Therapy Combination FEMALE Hepatitis B Chronic Humans INTERFERON-ALPHA LAMIVUDINE Male Middle Aged Reverse Transcriptase Inhibitors Treatment Outcome

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