TRIGONELLINE

作品数：9被引量：17H指数：3
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Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors
《Asian Pacific Journal of Tropical Biomedicine》2025年第1期34-42,共9页Zhi-Lan Ye Yuan Cao 
Objective:To assess the protective effects of trigonelline against spinal cord injury(SCI)in rats.Methods:Rats(Sprague-Dawley,male)were randomly assigned to seven groups(n=15 per group):normal,sham,SCI control(1%DMSO)...
关键词：BAX Bcl-2 BDNF COX-Ⅱ Spinal cord injury TRIGONELLINE 
Trigonelline mitigates bleomycin-induced idiopathic pulmonary fibrosis in mice
《Asian Pacific Journal of Tropical Biomedicine》2024年第9期391-400,I0008-I0291,共294页Swapnil Gavhane Chandrakant Gawli Sachin Kumar Biswajit Das Gayatri Marathe Vishal S.Patil Harun M.Patel Basavaraj Bommanahalli Chanakya Nath Kundu Chandragouda R.Patil 
Objective:To evaluate the effect of trigonelline on bleomycin-induced idiopathic pulmonary fibrosis(IPF)and to explore its underlying mechanisms using network pharmacology.Methods:IPF was induced in C57BL/6 mice by a ...
关键词：TRIGONELLINE Idiopathic pulmonary fibrosis ANTIFIBROTIC BLEOMYCIN Network pharmacology 
Increase of Trigonelline in Trigonella persica Plant under Drought Stress
《Journal of Botanical Research》2022年第2期19-25,共7页Fatemeh Zarinkamar Reyhaneh Medhat Maryam Rezayian 
Trigonella persica is a valuable medicinal plant which comprises trigonelline that is secondary metabolite and important component in cosmetic and medicine.This research was conducted in order to evaluation the drough...
关键词：Anatomical changes DROUGHT ROOT Trigonella persica TRIGONELLINE 
Effects of trigonelline inhibition of the Nrf2 transcription factor M vitro on Echmococcus granulosus被引量：4
《Acta Biochimica et Biophysica Sinica》2017年第8期696-705,共10页Wenjuan Qin Dongfang Guan Rongji Ma Rentan Yang Guoqiang Xing Hongjuan Shi Guangyao Tang Jiajie Li Hailong Lv Yufeng Jiang 
The aim of this study was to investigate the impact of trigonelline （TRG） on Echinococcus granulo- sus, and to explore the inhibition impact of nuclear factor erythroid-2-related factor 2 （Nrf2） signal- ing pathwa...
关键词：Echinococcus granulosus protoscoleces NRF2 TRG IMMUNOLOCALIZATION 
Stress Responses of Peanut (<i>Arachis hypogaea</i>L.) Genotypes as Measured by Trigonelline Content after Exposure to UV-B Radiation
《American Journal of Plant Sciences》2017年第5期998-1010,共13页David Willmon Amith R. Devireddy Madhuri Inupakutika Naveen Puppala Youngkoo Cho 
UV-B radiation has been widely documented as a stressor for plants that can cause decreased biomass, reduction in photosynthesis, and oxidative stress. Trigonelline is a secondary metabolite that is biosynthesized in ...
关键词：ABIOTIC Stress ARACHIS HYPOGAEA L. TRIGONELLINE UV-B 
Protection effect of trigonelline on liver of rats with non-alcoholic fatty liver diseases被引量：3
《Asian Pacific Journal of Tropical Medicine》2015年第8期639-642,共4页Dong-Fang Zhang Fan Zhang Jin Zhang Rui-Ming Zhang Ran Li 
supported by Natural Science Fund of Shandong Province(No.:ZR2009CL018)
Objective: To study the effect of trigonelline on the change of indicators of serum transaminase, lipoprotein and liver lipid of model rats with non-alcoholic fatty liver diseases and on the expression level of Bcl-2 ...
关键词：TRIGONELLINE Non-alcoholic FATTY LIVER DISEASES Bcl-2 BAX 
Trigonelline protects the cardiocyte from hydrogen peroxide induced apoptosis in H9c2 cells被引量：10
《Asian Pacific Journal of Tropical Medicine》2015年第4期263-268,共6页Soundharrajan Ilavenil Da Hye Kim Young-Il Jeong Mariadhas Valan Arasu Mayakrishnan Vijayakumar Ponnuraj Nagendra Prabhu Srisesharam Srigopalram Ki Choon Choi 
Objective:To elucidate the key parameters associated with hydrogen peroxide induced oxidative stress and investigates the mechanism of trigonelline(TG)for reducing the H_2O_2induced toxicity in H9c2 cells.Methods:Cyto...
关键词：TRIGONELLINE H9C2 cells ANTIOXIDANT Apoptosis CARDIOVASCULAR diseases 
Antibacterial Effect of Aqueous Extracts and Bioactive Chemical Compounds of <i>Coffea canephora</i>against Microorganisms Involved in Dental Caries and Periodontal Disease
《Advances in Microbiology》2014年第14期978-985,共8页Flávia M. da Silva Natalia L. P. Iorio Leandro A. Lobo Kátia Regina N. dos Santos Adriana Farah Lucianne C. Maia Andréa G. Antonio 
This study aimed to evaluate the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Coffea canephora aqueous extract (Cc), trigonelline (Tg) and 5-caffeoylquinic acid (5-CQA) agains...
关键词：Oral PATHOGENS Dental CARIES PERIODONTAL Disease Coffee TRIGONELLINE Chorogenic Acid 
Quantitative analysis of trigonelline in some Annona species by proton NMR spectroscopy被引量：1
《Natural Products and Bioprospecting》2013年第4期158-160,共3页Alan Rodrigues Teixeira MACHADO Gisele Avelar LAGE Felipe da Silva MEDEIROS José Dias de Souza FILHO Lúcia Pinheiro Santos PIMENTA 
We thank FAPEMIG for their financial support and CAPES for the fellowship of ARTM.
A quantitative ^(1)H NMR method(qHNMR)was used to measure the trigonelline content in the leaves of six species of the Annona genus.The methodology employed compared the intensities of the signals at δ9.14(H-2)andδ0...
关键词：TRIGONELLINE ANNONA quantitative^(1)H NMR 
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