AGONISTS

作品数:136被引量:373H指数:10
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相关领域:医药卫生更多>>
相关作者:王昊刘洪瑞李智郭政东蒋华良更多>>
相关机构:北京大学中国医科大学中国科学院北京中医药大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划SA-SIBS优秀人才奖励基金更多>>
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The Association between GLP-1 Receptor-Based Agonists and the Incidence of Asthma in Patients with Type 2 Diabetes and/or Obesity:A Meta-Analysis
《Biomedical and Environmental Sciences》2024年第6期607-616,共10页Mengqing Zhang Chu Lin Xiaoling Cai Ruoyang Jiao Shuzhen Bai Zonglin Li Suiyuan Hu Fang Lyu Wenjia Yang Linong Ji 
supported by The Beijing Natural Science Foundation[No.7202216];the National Natural Science Foundation of China[No.81970698 and No.81970708].
Objective Recent studies have indicated potential anti-inflammatory effects of glucagon-like peptide-1 receptor agonists(GLP-1RAs)on asthma,which is often comorbid with type 2 diabetes mellitus(T2DM)and obesity.Theref...
关键词:Glucagon-like peptide-1 receptor agonists Twincretins ASTHMA Type 2 diabetes mellitus OBESITY 
Are TrkB receptor agonists the right tool to fulfill the promises for a therapeutic value of the brain-derived neurotrophic factor?被引量:5
《Neural Regeneration Research》2024年第1期29-34,共6页Marta Zagrebelsky Martin Korte 
Brain-derived neurotrophic factor signaling via its receptor tro pomyosin receptor kinase B regulates several crucial physiological processes.It has been shown to act in the brain,promoting neuronal survival,growth,an...
关键词:Alzheimer's disease brain-derived neurotrophic factor DEPRESSION Parkinson's disease tropomyosin receptor kinase B receptor 
Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson’s disease被引量:3
《Neural Regeneration Research》2021年第6期1099-1104,共6页Steven Vetel Laura Foucault-Fruchard Claire Tronel Frédéric Buron Jackie Vergote Sylvie Bodard Sylvain Routier Sophie Sérrière Sylvie Chalon 
supported by Inserm(to SV,LFF,CT,JV,SB,SS,SC);by the Labex IRON(ANR-11-LABX-18-01:to all authors).
To date there is no treatment able to stop or slow down the loss of dopaminergic neurons that characterizes Parkinson’s disease.It was recently observed in a rodent model of Alzheimer’s disease that the interaction ...
关键词:6-HYDROXYDOPAMINE astrocytes microglial activation neurodegeneration neuroinflammation nicotinicα7 receptor Parkinson’s disease PHA 543613 PRE-084 sigma-1 receptor 
Cholestatic liver diseases:An era of emerging therapies被引量:6
《World Journal of Clinical Cases》2019年第13期1571-1581,共11页Hrishikesh Samant Wuttiporn Manatsathit David Dies Hosein Shokouh-Amiri Gazi Zibari Moheb Boktor Jonathan Steve Alexander 
Recently the field of cholestasis has expanded enormously reflecting an improved understanding of the molecular mechanisms underlying bile secretion and its perturbation in chronic cholestatic disease. Novel anti-chol...
关键词:BILE ACIDS DRUG therapy Cholestatic liver disease Nuclear RECEPTOR AGONISTS 
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