Clostridium difficile infection(CDI)has been increasing due to the effect of recurrent hospitalizations.The use of antibiotics has been shown to alter the gut microbiome and lead to CDIs.The treatment is limited to th...
funded as a key clinical project of Peking University Third Hospital [No. BYSY2018021];funded by Beijing Natural Science Foundation [7212128]。
Objective This study aimed to evaluate the clinical benefits of a vancomycin dosage strategy based on a serum trough concentration model in elderly patients.Methods This prospective single-center, open-label, randomiz...
the Beijing Tongren Hospital,Capital Medical University Institutional Review Board(Approval No.TRECKY2020-100).
BACKGROUND Vancomycin and teicoplanin are both antibiotics that have significant antimicrobial effects on Gram-positive cocci.AIM To explore the value of teicoplanin combined with conventional(vancomycin only)anti-inf...
Introduction Pouchitis is a common complication in those with restorative proctocolectomy with ileal pouch–anal anastomosis(IPAA).Some patients may develop chronic antibiotic-refractory pouchitis and its management c...
The Inner Mongolia Autonomous Region People's Hospital Training Talent Research Start-up Fund,No.BS201703.
BACKGROUND Thrombocytopenia is a serious complication in the medical practice of numerous drugs.Vancomycin is frequently used for the prophylaxis and treatment of suspected or identified methicillin-resistant positive...
Aim: To evaluate morbidity and mortality rate, clinical cure rate and cost of linezolid versus vancomycin in patients who have hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP) or Healthcare-ass...
Background: Complicated skin and skin structure infections (cSSSIs) due to Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), are associated with significant morbidity. Re-ducing MRSA carriage ha...
We present a case of Staphylococcus aurous tricuspid valve endocarditis without any risk factors (intravenous drug users, with pacemaker or central venous lines and with congenital heart disease). Transthoracic echoca...
Enterococci are important causes of community and healthcare-associated infections and are associated with hospital outbreaks amongst vulnerable and compromised patients.These organisms have relatively low virulence b...
Helicobacter pylori(H.pylori)is one of the most common chronic bacterial infections in humans,affecting half of world’s population.Therapy for H.pylori infection has proven to be both effective and safe.The oneweek t...