BACKGROUND Chronic pouchitis remains a significant and prevalent complication following ileal pouch-anal anastomosis in patients with ulcerative colitis.AIM To identify potential risk factors for the development of ch...
Background:In patients with inflammatory bowel disease(IBD)for whom medical therapy is unsuccessful or who develop colitis-as-sociated neoplasia,restorative proctocolectomy with ileal pouch-anal anastomosis(IPAA)is of...
Experimental evidence supports the fact that changes in the bowel microflora due to environmental or dietary factors have been investigated as implicating factors in the etiopathogenesis of inflammatory bowel disease(...
Inflammatory bowel disease(IBD)is a chronic condition that requires continuous medical treatment.To date,the medical management of patients with moderatelyto-severely active IBD who develop dependence or resistance to...
Introduction Pouchitis is a common complication in those with restorative proctocolectomy with ileal pouch–anal anastomosis(IPAA).Some patients may develop chronic antibiotic-refractory pouchitis and its management c...
Inflammatory bowel diseases(IBD)include a spectrum of chronic inflammatory disorders of the gastrointestinal tract whose pathogenesis is yet to be elucidated.The intestinal microbiome has been studied as a causal comp...
BACKGROUND Refractory pouchitis is a common cause of pouch failure,which may require surgical excision of the pouch or permanent diversion.We aimed to show the effect of vedolizumab on treatment of the patient with re...
Background:Chronic antibiotic-refractory pouchitis(CARP)is a complication of ileal pouch-anal anastomosis(IPAA),which poses a therapeutic challenge.Vedolizumab,a gut-selective monoclonal antibody to the a4b7 of integr...
Background:In symptomatic patients with an ileal pouch,stool studies are often sent to diagnose enteric pathogens.Aim of this study is to find the value of routine stool studies in the evaluation of symptomatic patien...