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LINKING: 作品数：472被引量：859H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵东风聂仁灿周冬明张明柳凌艳更多>>; 相关机构：华中师范大学南京大学云南大学宿州学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Network-level time computations in the suprachiasmatic nucleus: 《Cell Research》2024年第7期471-472,共2页Natalie Ness Marco Brancaccio; Deciphering neuronal circuit dynamics is critical for understanding how the brain encodes information.In a recent study in Cell Research,Wang et al.shed light on how neuronal ensemble activity encodes time in the supr...; 关键词：supra maintained LINKING

Aberrant phase separation:linking IDR mutations to disease: 《Cell Research》2023年第8期583-584,共2页Rashik Ahmed Julie D.Forman-Kay; In a recent Nature paper,Mensah et al.demonstrate that a significant subset of frameshift mutations in C-terminal intrinsically disordered regions(IDRs)can alter phase separation propensities,cause protein mislocaliza...; 关键词：function SEPARATION LINKING

Adaptation to MOMP drives cancer persistence: 《Cell Research》2023年第2期93-94,共2页Emma Guilbaud Lorenzo Galluzzi; While widespread mitochondrial outer membrane permeabilization(MOMP)generally seals the fate of stressed cancer cells as it elicits caspase-dependent mechanisms that regulate the kinetics and immunological manifestati...; 关键词：MOMP CANCER LINKING

AHI1: linking depression and impaired antiviral immune response: 《Cell Research》2022年第10期869-870,共2页Weili Yang Shihua Li Xiao-Jiang Li; AHI1 is a neurodevelopmental gene,and its expression deficiency was found to correlate with altered stress responses and depressive behaviors in mice.In a recent paper of Cell Research,Zhang et al.show that AHI1 reduc...; 关键词：AHI IMPAIRED immunity

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer被引量：29: 《Cell Research》2022年第5期477-490,共14页Yi Xiao Ding Ma Yun-Song Yang Fan Yang Jia-Han Ding Yue Gong Lin Jiang Li-Ping Ge Song-Yang Wu Qiang Yu Qing Zhang François Bertucci Qiuzhuang Sun Xin Hu Da-Qiang Li Zhi-Ming Shao Yi-Zhou Jiang; the National Key R&D Project of China(2020YFA0112304),the National Natural Science Foundation of China(81922048,82002792,82002802,82072922 and 91959207);the Program of Shanghai Academic/Technology Research Leader(20XD1421100);the Shanghai Key Laboratory of Breast Cancer(12DZ2260100);the Clinical Research Plan of SHDC(SHDC2020CR4002,SHDC2020CR5005);Shanghai Sailing Program(20YF1408600 and 20YF1408700)。; Metabolic reprogramming is a hallmark of cancer.However,systematic characterizations of metabolites in triple-negative breast cancer(TNBC)are still lacking.Our study profiled the polar metabolome and lipidome in 330 T...; 关键词：BREAST LINKING TOGETHER

Aldolase is a sensor for both low and high glucose,linking to AMPK and mTORC1被引量：1: 《Cell Research》2021年第4期478-481,共4页Mengqi Li Chen-Song Zhang Jin-Wei Feng Xiaoyan Wei Cixiong Zhang Changchuan Xie Yaying Wu Simon A.Hawley Abdelmadjid Atrih Douglas J.Lamont Zhichao Wang Hai-Long Piao D.Grahame Hardie Sheng-Cai Lin; This work was supported by grants from the National Natural Science Foundation of China(#91854208,#31922034,#32070753,#31730058,#2020J02003);the Fundamental Research Funds for the Central Universities(#20720200069);Shanghai Key Laboratory of Diabetes Mellitus(#SHKLD-KF-1703);the Project“111”sponsored by the State Bureau of Foreign Experts and Ministry of Education of China(#BP2018017);the XMU Training Program of Innovation and Entrepreneurship for Undergraduates(2019×0666)to S.-C.L.;by the Wellcome Trust(204766/Z/16/Z)to D.G.H.; Dear Editor,As well as glucose being the major carbon nutrient for most cells,its availability also acts as a gate-keeper exerting a switch between anabolic and catabolic metabolism,with the protein kinases mTORC1 and...; 关键词：METABOLISM mTORC1 HOMEOSTASIS

Linking vitamin B12 and a trembling disorder: 《Cell Research》2019年第5期343-344,共2页Ralph Green Chadwick W.Christine; Hyperactivity of LRRK2,a multifunctional serine/threonine protein kinase,is central to Parkinson's disease pathogenesis.Vitamin B12 turns out to be a potent inhibitor of its undesirable activity.An estimated 7-10 mill...; 关键词：LINKING B12 DISORDER

SETD2- linking stem cell survival and transformation被引量：1: 《Cell Research》2018年第4期393-394,共2页Mrinal M. Patnaik Omar Abdel-Wahab; SETD2 encodes a histone H3 lysine 36 （H3K36） methyltrans- ferase affected by mutations and deletions in a wide variety of cancers. Whether SETD2 loss alone can initiate tumorigenesis has not been established previou...; 关键词：干细胞连接症候群白血病

FTO： linking m^6A demethylation to adipogenesis被引量：10: 《Cell Research》2015年第1期3-4,共2页Moshe Shay Ben-Haim Sharon Moshitch-Moshkovitz Gideon Rechavi; Polymorphism of the FTO gene encoding an N^6-methyladenosine （m^6A） RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role i...; 关键词：脂肪形成 FTO 去甲基化平方连接基因编码甲基化酶控制调节

Linking SOXIO to a slow-growth resistance phenotype被引量：1: 《Cell Research》2014年第8期906-907,共2页Gao Zhang; Slow-cycling BRAF^V600E melanoma cells are notoriously resistant to standard chemotherapy or targeted therapy but the underlying mechanism remains elusive. Now a new study unlocks this mystery and offers novel insigh...; 关键词：表型耐药链接黑色素细胞靶向治疗自行车抵抗力化疗

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