IMMUNOCHEMOTHERAPY

作品数：27被引量：71H指数：5
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Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery
《World Journal of Gastrointestinal Oncology》2025年第3期91-103,共13页Tian-Hao Li Xiong Sun Cheng-Guo Li Yu-Ping Yin Kai-Xiong Tao 
Natural Science Foundation of Hubei Province of China,No.2024AFB655;Key Research and Development Program of Hubei Province of China,No.2021BCA116;National Natural Science Foundation of China,No.82072736,No.82003205,No.
BACKGROUND Coagulation status is closely related to the progression of malignant tumors.In the era of neoadjuvant immunochemotherapy(NICT),the prognostic utility of coagulation indicators in patients with locally adva...
关键词：Locally advanced gastric cancer COAGULATION Neoadjuvant immunochemotherapy PROGNOSIS Radical gastrectomy 
Continuous R-DA-EDOCH alternated with high-dose Ara-C induces deep remission and overcomes high-risk factors in young patients with newly diagnosed mantle cell lymphoma
《Cancer Biology & Medicine》2025年第2期177-189,共13页Yi Wang Yuting Yan Dandan Shan Jiawen Chen Wei Liu Tingyu Wang Gang An WeiweiSui Wenyang Huang Wenjie Xiong Huimin Liu Qi Sun Huijun Wang Zhijian Xiao JianxiangWang Lugui Qiu Dehui Zou Shuhua Yi 
supported by grants from the National Natural Science Foundation of China(Grant Nos.82200215,82170193,and 82370197);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Grant No.2022-I2M-1-002)。
Objective:Our previous studies have indicated potentially higher proliferative activity of tumor cells in Chinese patients with mantle-cell lymphoma(MCL)than those in Western.Given the success and tolerability of R-DA...
关键词：Mantle cell lymphoma IMMUNOCHEMOTHERAPY high-risk factors minimal residual disease adverse events 
Biodegradable nanoparticles-mediated targeted drug delivery achieves trans-spatial immunotherapy
《Fundamental Research》2024年第6期1639-1649,共11页Yi Wang Min Qian Yibo Xie Xiaoyi Zhang Yanhui Qin Rongqin Huang 
supported by National Natural Science Foundation of China(82172746);Program of Shanghai Academic Research Leader(20XD1420500);Natural Science Foundation of Shanghai(20ZR1401800);Jiangsu Provincial Science and Technology Department Social Development-Clinical Frontier Technology(BE2020769).
Immunotherapy has been seriously retarded due to inadequate antigen presentation and a tumor cell-dominated immunosuppressive microenvironment(TME).Herein,biodegradable multifunctional mesoporous silica nanopar-ticles...
关键词：BIOMATERIALS IMMUNOCHEMOTHERAPY Targeted drug delivery Trans-spatial antigen presentation Biodegradabiity 
Computed tomography-based radiomic model for the prediction of neoadjuvant immunochemotherapy response in patients with advanced gastric cancer
《World Journal of Gastrointestinal Oncology》2024年第10期4115-4128,共14页Jun Zhang Qi Wang Tian-Hui Guo Wen Gao Yi-Miao Yu Rui-Feng Wang Hua-Long Yu Jing-Jing Chen Ling-Ling Sun Bi-Yuan Zhang Hai-Ji Wang 
Supported by the Affiliated Hospital of Qingdao University Horizontal Fund,No.3635;Intramural Project Fund,No.4618.
BACKGROUND Neoadjuvant immunochemotherapy(nICT)has emerged as a popular treatment approach for advanced gastric cancer(AGC)in clinical practice worldwide.However,the response of AGC patients to nICT displays significa...
关键词：Gastric cancer Radiomics Computed tomography Neoadjuvant immunochemotherapy Machine learning IMMUNOLOGY 
Perioperative toripalimab plus neoadjuvant chemotherapy might improve outcomes in resectable esophageal cancer:an interim analysis of a phase Ⅲ randomized clinical trial被引量：1
《Cancer Communications》2024年第10期1214-1227,共14页Yan Zheng Guanghui Liang Dongfeng Yuan Xianben Liu Yufeng Ba Zimin Qin Sining Shen Zhenxuan Li Haibo Sun Baoxing Liu Quanli Gao Peng Li Zongfei Wang Shilei Liu Jianping Zhu Haoran Wang Haibo Ma Zhenzhen Liu Fei Zhao Jun Zhang He Zhang Daoyuan Wu Jinrong Qu Jie Ma Peng Zhang Wenjie Ma Ming Yan Yongkui Yu Qing Li Jiangong Zhang Wenqun Xing 
Central Plains Young Top Talent,Grant/Award Number:2022;Henan Province Medical Science and Technology Key Projects Coconstructed by the Ministry of Health,Grant/Award Number:SBGJ202102059;Wu Jieping Medical Foundation,Grant/Award Number:320.6750.2020-15-1;Henan Province Health Science and Technology Innovation Outstanding Young Talent Training Project,Grant/Award Number:YXKC2021029;National Natural Science Foundation of China,Grant/Award Number:82002521。
Background:In the era of immunotherapy,neoadjuvant immunochemotherapy(NAIC)for the treatment of locally advanced esophageal squamous cell carcinoma(ESCC)is used clinically but lacks of high-level clinical evidence.Thi...
关键词：esophageal squamous cell carcinoma minimally invasive esophagectomy neoadjuvant chemotherapy neoadjuvant immunochemotherapy survival 
Impact of baseline steroids on the efficacy of neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma
《World Journal of Gastrointestinal Oncology》2024年第9期3887-3897,共11页Yuan-Heng Huang Guo-Zhen Yang Hui-Guo Chen Xiao-Jun Li Yong-Hui Wu Kai Zhang Jian-Nan Xu Jian Zhang 
BACKGROUND Immunochemotherapy involving the combination of programmed cell death 1/programmed cell death ligand 1 inhibitors with chemotherapy has advanced the treatment of locally advanced esophageal squamous cell ca...
关键词：Esophageal squamous cell carcinoma Neoadjuvant immunochemotherapy DEXAMETHASONE ANTIHISTAMINES Treatment efficacy 
Immunochemotherapy combined with novel agents for Richter syndrome:report of 3 cases
《Holistic Integrative Oncology》2023年第1期385-389,共5页Lijie Xing Hui Wang Dan Liu Qiang He Zengjun Li 
funded by the National Natural Science Foundation of China(82200224 to LX);the Natural Science Foundation of Shandong Province(ZR2021MH072 to LX).
Objective Richter syndrome(RS)occurs in approximately 2–10%of chronic lymphocytic leukemia(CLL)patients,more often during the disease course than at diagnosis,with a diffuse large B-cell Lymphoma(DLBCL)histology in 9...
关键词：Richter syndrome DLBCL BTK inhibitor BCL2 inhibitor IMMUNOTHERAPY 
Lenvatinib-and vadimezan-loaded synthetic high-density lipoprotein for combinational immunochemotherapy of metastatic triple-negative breast cancer被引量：3
《Acta Pharmaceutica Sinica B》2022年第9期3726-3738,共13页Chao Zheng Wen Zhang Jinming Wang Yihui Zha Fengqin Xiong Ying Cai Xiang Gong Binyu Zhu Helen He Zhu Hao Wang Yaping Li Pengcheng Zhang 
the National Natural Science Foundation of China (32171374, 31870995 and 81671808);the Shandong Provincial Natural Science Foundation (ZR2019ZD25, China) for financial support
Metastatic triple-negative breast cancer(TNBC)is the most aggressive type of breast cancer.Combination of systemic chemotherapy and immune checkpoint blockade is effective but of limited benefit due to insufficient in...
关键词：High-density lipoprotein IMMUNOTHERAPY Combination therapy METASTASIS Triple-negative breast cancer Lenvatinib Vadimezan Immune checkpoint blockad 
Primary adrenal diffuse large B-cell lymphoma with normal adrenal cortex function:A case report被引量：1
《World Journal of Clinical Cases》2022年第2期709-716,共8页Zhi-Nan Fan Hong-Jin Shi Bo-Bo Xiong Jin-Song Zhang Hai-Feng Wang Jian-Song Wang 
Supported by National Natural Science Foundation of China,No.82060464 and No.81972395.
BACKGROUND Diffuse large B-cell lymphoma,which accounts for about approximately 30%to 40%of non-Hodgkin's lymphomas,is the most common type and is a class of aggressive B-cell lymphomas.However,diffuse large B-cell ly...
关键词：Large B-cell lymphoma Adrenal glands IMMUNOCHEMOTHERAPY Surgical procedures Case report 
Leveraging immunochemotherapy for treating pancreaticcancer
《Cell Research》2021年第12期1228-1229,共2页Anushka Dongre Robert A.Weinberg 
The refractory response of pancreatic ductal adenocarcinoma(PDAC)to multiple treatment regimens can be attributed to the presence of a desmoplastic stroma together with an immunosuppressive tumor microenvironment.In a...
关键词：CHEMOTHERAPY ADENOCARCINOMA 
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