相关期刊:《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Chinese Journal of Chemistry》《Journal of Hainan Medical University》《Defence Technology(防务技术)》更多>>
support from the National Natural Science Foundation of China(Grant No.22075143,21875110);the Science Challenge Project(Grant No.TZ2018004);the Qing Lan Project for the grant。
In light of the low yields and complex reaction routes of some well-known 5,5-fused and 5,6-fused bicyclic compounds,a series of 5,7-fused bicyclic imidazole-diazepine compounds were developed with high yields by only...
Beijing University of Chemical Technology-China-Japan Friendship Hospital Joint Fund (PYBZ1710)
Objective: To establish a mouse model of skin squamous cell carcinoma induced by high dose 7, 12-dimethyl-benzodiazepine [a] anthracene, and to provide experimental basis for the prevention and treatment of skin squam...
supported by NIH/NINDS Grant R01 NS060812;a grant from Muscular Dystrophy Association(MDA)
2,3-Benzodiazepine(2,3-BDZ) compounds represent a group of structurally diverse,smallmolecule antagonists of(R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid(AMPA)receptors.Antagonists of AMPA receptors ...
financial support from the National Natural Science Foundation of China(No.21276064);the Natural Science Foundation of Hebei Education Department(No.2008320);the Science Foundation of Hebei Normal University(No.2011Y04)
A general, mild and efficient protocol for the synthesis of ethyl 4-methyl-2-(thiophen)-2,5-dihydro-1,5- benzodiazepine-3-carboxylate is achieved for first time using H3PMo12O40 in ethanol at 0 ℃ by a one- pot, th...
Borax/phosphorous oxychloride (BPO) efficiently catalyzes the preparation of 1,5-benzodiazepine derivatives of o-phenylenediamines and ketones in solvent-free and solution conditions. The reaction proceeds efficient...
Project supported by the Natural Science Foundation of Zhejiang Province (No. Y407168);the Foundation of Education of Zhejiang Province (No. Z200803599);the Opening Foundation of Zhejiang Provincial Top Key Discipline (No. 56310101634), China
Both 1,5-benzodiazepine and quinoxaline derivatives are important heterocycles in pharmaceuticals. We describe an efficient and clean method for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones...
1,5-Benzodiazepine derivatives have been synthesized by the condensation of o-phenylenediamines and ketones in the presence of boric acid as catalyst under mild conditions. This method is simple, environmentally benig...
MgBr2 performs as a novel catalyst for the synthesis of various 1,5-benzodiazepine derivatives from wide range of substituted o- phenylenediamines and various ketones in good to excellent isolated yields (93-98%) us...
Sulfanilic acid has been found to be an efficient catalyst for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones. This method is simple, effective and environmentally friendly and gives better y...
A simple and high yielding method for the integration of 1,5-benzodiazepines integrated with 5-methyl- 2-oxo-3-phenyl-△^4-1,3,4-oxadiazolines in 75%-90% yield by microwave irradiation is devised. Microwave-accelerate...