DIAZEPINE

作品数:18被引量:5H指数:1
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相关领域:理学化学工程更多>>
相关机构:上海应用技术大学更多>>
相关期刊:《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Chinese Journal of Chemistry》《Journal of Hainan Medical University》《Defence Technology(防务技术)》更多>>
相关基金:国家自然科学基金河北省自然科学基金更多>>
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The skeleton of 5,7-fused bicyclic imidazole-diazepine for heat-resistant energetic materials
《Defence Technology(防务技术)》2023年第9期193-199,共7页Xiaoxiao Zheng Yubing Xue Changhao Dai Hongwei Yang Guangbin Cheng 
support from the National Natural Science Foundation of China(Grant No.22075143,21875110);the Science Challenge Project(Grant No.TZ2018004);the Qing Lan Project for the grant。
In light of the low yields and complex reaction routes of some well-known 5,5-fused and 5,6-fused bicyclic compounds,a series of 5,7-fused bicyclic imidazole-diazepine compounds were developed with high yields by only...
关键词:Imidazole-diazepine Heat-resistant material 5 7-Fused skeleton Energetic materials 
Establishment and evaluation of a mouse model of skin squamous cell carcinoma induced by 7, 12-dimethyl-benzodiazepine [a] anthracene at high dose
《Journal of Hainan Medical University》2020年第2期12-16,共5页Nan Liu Ao Wang Yan-Ping Bai 
Beijing University of Chemical Technology-China-Japan Friendship Hospital Joint Fund (PYBZ1710)
Objective: To establish a mouse model of skin squamous cell carcinoma induced by high dose 7, 12-dimethyl-benzodiazepine [a] anthracene, and to provide experimental basis for the prevention and treatment of skin squam...
关键词:squamous cell carcinoma DMBA 7 12-dimethyl-benzodiazepine[a] anthracene Mouse model 
Mechanism-based design of 2,3-benzodiazepine inhibitors for AMPA receptors
《Acta Pharmaceutica Sinica B》2015年第6期500-505,共6页Li Niun 
supported by NIH/NINDS Grant R01 NS060812;a grant from Muscular Dystrophy Association(MDA)
2,3-Benzodiazepine(2,3-BDZ) compounds represent a group of structurally diverse,smallmolecule antagonists of(R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid(AMPA)receptors.Antagonists of AMPA receptors ...
关键词:AMPA receptors 2 3-Benzodiazepine derivatives Subunit-selective antagonists RNA aptamers 
Highly efficient one-pot,three-component synthesis of1,5-benzodiazepine derivatives被引量:1
《Chinese Chemical Letters》2014年第2期327-332,共6页Xiao-Qing Li Lan-Zhi Wang 
financial support from the National Natural Science Foundation of China(No.21276064);the Natural Science Foundation of Hebei Education Department(No.2008320);the Science Foundation of Hebei Normal University(No.2011Y04)
A general, mild and efficient protocol for the synthesis of ethyl 4-methyl-2-(thiophen)-2,5-dihydro-1,5- benzodiazepine-3-carboxylate is achieved for first time using H3PMo12O40 in ethanol at 0 ℃ by a one- pot, th...
关键词:ONE-POT Synthesis 1 5-Benzodiazepine derivative 
A New and Efficient Procedure for Synthesis of 1,5-Benzodiazepine Derivatives in Solution and under Solvent-Free Conditions
《Chinese Journal of Chemistry》2011年第6期1290-1293,共4页Gholivand, Khodayar Zare, Karim Jafari, Hadi Adibi, Hadi 
Borax/phosphorous oxychloride (BPO) efficiently catalyzes the preparation of 1,5-benzodiazepine derivatives of o-phenylenediamines and ketones in solvent-free and solution conditions. The reaction proceeds efficient...
关键词:1 5-benzodiazepine O-PHENYLENEDIAMINE BORAX phosphorus oxychloride 
Sodium tetrachloroaurate(III) dihydrate-catalyzed efficient synthesis of 1,5-benzodiazepine and quinoxaline derivatives
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2010年第2期102-108,共7页Ren-xin SHI Yun-kui LIU Zhen-yuan XU 
Project supported by the Natural Science Foundation of Zhejiang Province (No. Y407168);the Foundation of Education of Zhejiang Province (No. Z200803599);the Opening Foundation of Zhejiang Provincial Top Key Discipline (No. 56310101634), China
Both 1,5-benzodiazepine and quinoxaline derivatives are important heterocycles in pharmaceuticals. We describe an efficient and clean method for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones...
关键词:1 5-benzodiaepines O-PHENYLENEDIAMINE KETONES QUINOXALINES Gold catalyst 
An efficient synthesis of 1,5-benzodiazepine derivatives catalyzed by boric acid被引量:2
《Chinese Chemical Letters》2009年第8期905-908,共4页Xin Zhou Mei Yue Zhang Shu Tao Gao Jing Jun Ma Chun Wang Chao Liu 
1,5-Benzodiazepine derivatives have been synthesized by the condensation of o-phenylenediamines and ketones in the presence of boric acid as catalyst under mild conditions. This method is simple, environmentally benig...
关键词:1 5-Benzodiazepincs O-PHENYLENEDIAMINES Boric acid Synthesis 
Novel,efficient,and green procedure for the synthesis of 1,5-benzodiazepines catalyzed by MgBr_2 in aqueous media被引量:1
《Chinese Chemical Letters》2009年第1期32-36,共5页Shivaji S.Pawar Murlidhar S.Shingare Shivaji N.Thore 
MgBr2 performs as a novel catalyst for the synthesis of various 1,5-benzodiazepine derivatives from wide range of substituted o- phenylenediamines and various ketones in good to excellent isolated yields (93-98%) us...
关键词:MgBr2 O-PHENYLENEDIAMINES KETONES Aqueous media 1 5-Benzodiazepine 
Sulfanilic acid catalyzed solvent-free synthesis of 1,5-benzodiazepine derivatives
《Chinese Chemical Letters》2007年第11期1305-1308,共4页Jaiprakash N.Sangshetti Nagnnath D.Kokare Devanand B.Shinde 
Sulfanilic acid has been found to be an efficient catalyst for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones. This method is simple, effective and environmentally friendly and gives better y...
关键词:1 5-Benzodiazepines Sulfanilic acid catalyst Solvent free condition 
A Rapid and Convenient Synthetic Route to Novel 1,5-Benzodiazepine Derivatives of 5-Methyl-3-phenyl-2-oxo-△^4-1,3,4-oxadiazolines from ρ-Acetylphenylsydnone and Their Pharmacological Activity
《Chinese Journal of Chemistry》2006年第1期79-84,共6页KAMBLE,Ravindra R. SUDHA, Belagur S. 
A simple and high yielding method for the integration of 1,5-benzodiazepines integrated with 5-methyl- 2-oxo-3-phenyl-△^4-1,3,4-oxadiazolines in 75%-90% yield by microwave irradiation is devised. Microwave-accelerate...
关键词:ρ-acetylphenylsydnone 1 3-dipolar cycloaddition 1 5-diazepine Michael addition microwave irradiation thermal method 
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