BACKGROUND Malignant hyperthermia(MH)is a hypermetabolic disorder of skeletal muscles triggered by exposure to volatile anesthetics and depolarizing muscular relaxants.It manifests with clinical presentations such as ...
the grant from the School-Level Scientific Research Projects supported by Shihezi University(No.ZZZC202076A).
Heavy metal poisoning is a major public health problem and the main cause of poisoning different systems of the human body[1].However,there are a relatively small number of studies on the effects of arsenic on the tra...
supported by the Department of Anesthesiology and Pain Medicine and NIH grant(No.UL1 TR001860)of the University of California Davis Health.
Malignant hyperthermia(MH) is a rare and life-threatening pharmacogenetic disorder triggered by volatile anesthetics, the depolarizing muscle relaxant succinylcholine, and rarely by strenuous exercise or environmental...
To the Editor: Malignant hyperthermia (MH) is a rare but potentially fatal, inherited skeletal muscle disorder that is mostly induced by the ingestion of the depolarizing relaxant, i.e., succinylcholine or volatile...
supported by a grant from the Guangdong Science&Technology Plan Program in China,No.2014A020212043;the a grant from the Shenzhen Science&Technology Plan Program in China,No.JCYJ20140414170821242;the a grant from Shenzhen Collaborative Innovation Plan Program in China,No.GJHZ20120614154914623;a grant from the Science&Technology Project of Shanxi Health and Family Planning Commission in China,No.201201060
Therapeutic hypothermia is the most promising non-pharmacological neuroprotective strategy against ischemic injury. However, shivering is the most common adverse reaction. Many studies have shown that dantrolene is ne...
Purpose: To examine the use of intravenous dantrolene in hospitalized patients. Materials and Methods: Medical Records of patients treated with intravenous dantrolene between 2007 and 2012 at 6 teaching hospitals were...
The mechanism of degradation of dantrolene in aqueous buffer solutions was studied at various pH values in the range of pH 1.2-9.5 and at temperatures ranging from 25℃ to 75℃ to determine the optimum pH and temperat...
Introduction: A rare and atypical form of Neuroleptic Malignant Syndrome (NMS) can be a deceptive and life threatening condition if not diagnosed properly in acute and critical care settings. Methods: The management o...
The effects of glutamate and its agonists and antagonists on the swelling of cultured astrocytes were studied. Swelling of astrocytes was measured by [3H]-O-methyl-D-glucose uptake. Glutamate at 0.5, 1 and 10mmol/L an...