DANTROLENE

作品数:10被引量:8H指数:1
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相关领域:医药卫生更多>>
相关作者:高艺更多>>
相关机构:吉林大学更多>>
相关期刊:《Science China(Life Sciences)》《Pharmacology & Pharmacy》《Open Journal of Anesthesiology》《Chinese Medical Journal》更多>>
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Malignant hyperthermia as a rare complication of local lidocaine injection:A case report
《World Journal of Anesthesiology》2023年第1期1-7,共7页Mukosolu Florence Obi Manveer Ubhi Vikhyath Namireddy Chelsea Noel Manjari Sharma Frederick N.Campos Yash Garg 
BACKGROUND Malignant hyperthermia(MH)is a hypermetabolic disorder of skeletal muscles triggered by exposure to volatile anesthetics and depolarizing muscular relaxants.It manifests with clinical presentations such as ...
关键词:Malignant hyperthermia TACHYARRHYTHMIA LIDOCAINE Local anesthesia Dantrolene sodium Genetic mutation Case report 
The effects of 2-aminoethoxydiphenyl borate and dantrolene on rat bones treated with NaAsO_(2)
《Acta Biochimica et Biophysica Sinica》2021年第9期1247-1249,共3页Jia Feng Wenjuan Qin Zhen Wang Zijing Zhai Rongji Ma Hailong Lv Yufeng Jiang 
the grant from the School-Level Scientific Research Projects supported by Shihezi University(No.ZZZC202076A).
Heavy metal poisoning is a major public health problem and the main cause of poisoning different systems of the human body[1].However,there are a relatively small number of studies on the effects of arsenic on the tra...
关键词:protective ARSENIC RATS 
The current status of malignant hyperthermia
《The Journal of Biomedical Research》2020年第2期75-85,共11页Lukun Yang Timothy Tautz Shulin Zhang Alla Fomina Hong Liu 
supported by the Department of Anesthesiology and Pain Medicine and NIH grant(No.UL1 TR001860)of the University of California Davis Health.
Malignant hyperthermia(MH) is a rare and life-threatening pharmacogenetic disorder triggered by volatile anesthetics, the depolarizing muscle relaxant succinylcholine, and rarely by strenuous exercise or environmental...
关键词:malignant hyperthermia general anesthesia DANTROLENE ryanodine receptor 
Freatment of Malignant Hyperthermia without Dantrolene in a 14-year-old Boy被引量:1
《Chinese Medical Journal》2017年第6期755-756,共2页Shu-Ting Liu Li-Fei Liu Shou-Yong Wang 
To the Editor: Malignant hyperthermia (MH) is a rare but potentially fatal, inherited skeletal muscle disorder that is mostly induced by the ingestion of the depolarizing relaxant, i.e., succinylcholine or volatile...
Dantrolene enhances the protective effect of hypothermia on cerebral cortex neurons
《Neural Regeneration Research》2015年第8期1279-1285,共7页Sui-yi Xu Feng-yun Hu Li-jie Ren Lei Chen Zhu-qing Zhou Xie-jun Zhang Wei-ping Li 
supported by a grant from the Guangdong Science&Technology Plan Program in China,No.2014A020212043;the a grant from the Shenzhen Science&Technology Plan Program in China,No.JCYJ20140414170821242;the a grant from Shenzhen Collaborative Innovation Plan Program in China,No.GJHZ20120614154914623;a grant from the Science&Technology Project of Shanxi Health and Family Planning Commission in China,No.201201060
Therapeutic hypothermia is the most promising non-pharmacological neuroprotective strategy against ischemic injury. However, shivering is the most common adverse reaction. Many studies have shown that dantrolene is ne...
关键词:nerve regeneration ischemic stroke oxygen-glucose deprivation fluorescent probe neurons flow cytometry apoptosis calcium overload reactive oxygen neural regeneration 
Dantrolene in the Treatment of Refractory Hyperthermic Conditions in Critical Care: A Multicenter Retrospective Study
《Open Journal of Anesthesiology》2015年第4期63-71,共9页Shonali C. Pawar Henry Rosenberg Robert Adamson Jennifer A. LaRosa Ronald Chamberlain 
Purpose: To examine the use of intravenous dantrolene in hospitalized patients. Materials and Methods: Medical Records of patients treated with intravenous dantrolene between 2007 and 2012 at 6 teaching hospitals were...
关键词:DANTROLENE MALIGNANT HYPERTHERMIA NEUROLEPTIC MALIGNANT Syndrome SEPSIS 
Stability Characterization, Kinetics and Mechanism of Degradation of Dantrolene in Aqueous Solution: Effect of pH and Temperature
《Pharmacology & Pharmacy》2012年第3期281-290,共10页Saeed R. Khan Mobin Tawakkul Vilayat A. Sayeed Patrick Faustino Mansoor A. Khan 
The mechanism of degradation of dantrolene in aqueous buffer solutions was studied at various pH values in the range of pH 1.2-9.5 and at temperatures ranging from 25℃ to 75℃ to determine the optimum pH and temperat...
关键词:DANTROLENE UPLC pH IMPURITY DEGRADATION Compound B C. 
Atypical Neuroleptic Malignant Syndrome: Pitfalls and Challenges in the Delirious Substance Abuser
《Open Journal of Anesthesiology》2012年第2期53-57,共5页Nirav N. Shah Kristin G. Fless Mikhail Litinski Fariborz Rezai Paul C. Yodice Henry Rosenberg 
Introduction: A rare and atypical form of Neuroleptic Malignant Syndrome (NMS) can be a deceptive and life threatening condition if not diagnosed properly in acute and critical care settings. Methods: The management o...
关键词:ATYPICAL NEUROLEPTIC Malignant Syndrome HALOPERIDOL ZIPRASIDONE DANTROLENE Rhabdomyolysis Creatinine Phosphokinase AMINOTRANSFERASE 
丹曲洛林(Dantrolene)保护亨廷顿氏病患者的神经元
《广东药学院学报》2011年第6期608-608,共1页温玉琴 
亨廷顿氏病(HD)的重要特征表现为大脑纹状体(该区域与运动和学习功能密切相关)和皮层功能退化。该疾病是由于蛋白的错误折叠引起,这些蛋白聚集最终形成巨大块状内含物。
关键词:亨廷顿氏病 神经元 患者 保护 蛋白聚集 功能退化 学习功能 脑纹状体 
Glutamate-induced swelling of cultured astrocytes is mediated by metabotropic glutamate receptor被引量:7
《Science China(Life Sciences)》1996年第5期517-522,共6页袁芳 王天佑 
Project supported by Ministry of Public Health.
The effects of glutamate and its agonists and antagonists on the swelling of cultured astrocytes were studied. Swelling of astrocytes was measured by [3H]-O-methyl-D-glucose uptake. Glutamate at 0.5, 1 and 10mmol/L an...
关键词:GLUTAMATE trans-ACPD ASTROCYTE SWELL DANTROLENE CA2+ 
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