AMINOTRANSFERASE

作品数：59被引量：261H指数：11
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相关领域：医药卫生更多>>
相关作者：王凤水程丹颖李贲罗爽邢卉春更多>>
相关机构：北京地坛医院广东医学院附属福田医院南开大学更多>>
相关期刊：《World Journal of Experimental Medicine》《World Journal of Gastroenterology》《World Journal of Clinical Cases》《Journal of Clinical and Translational Hepatology》更多>>
相关基金：国家自然科学基金国家科技重大专项中国博士后科学基金国家重点基础研究发展计划更多>>
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Effects of microbe-derived antioxidants on growth,digestive and aminotransferase activities,and antioxidant capacities in the hepatopancreas of Eriocheir sinensis under ammonia nitrogen stress
《Aquaculture and Fisheries》2024年第6期957-966,共10页Aoya Shi Huan Ma Xingliang Shi Wenquan Zhou Wangjun Pan Yameng Song Qing Chen Xiaowen Yu Chao Niu Yingfei Yang Yongxu Cheng Xiaozhen Yang 
the support of the National Key R&D Program of China(2019YFD0900105);the capacity-promoting Project of Shanghai Engineering and Technology Center from Shanghai Municipal Science and Technology Commission(No.19DZ2284300);the National Natural Science Foundation of China(grant number No 41876190);the Fishery Science and Technology Projects in Jiangsu Province(grant number d2018_4);the Shandong Joint Fund(grant number U1706209);the Aquaculture Engineering Research Platform in Shanghai,established by the Shanghai Science and Technology Commission(grant number 16DZ2281200);supported by China Agriculture Research System of MOF and MARA,the program for Shanghai Collaborative Innovation Center for Cultivating Elite Breeds and Green-culture of Aquaculture animals(No.2021-KJ-02-12);industry-leading talent project of Yellow River Delta.(DYRC20190210).
This study evaluated the effects of feeding a microbial-derived antioxidant diet(MA)for 56 days on the growth performance of Eriocheir sinensis,as well as on digestive and metabolic enzyme activity and antioxidant cap...
关键词：Eriocheir sinensis Microbial-derived antioxidant GROWTH Ammonia nitrogen 
Development of an Engineered Sugar Aminotransferase with Simultaneously Improved Stability and Non-Natural Substrate Activity to Synthesize the Glucosidase Inhibitor Valienamine
《Engineering》2024年第11期185-195,共11页Runxi Wang Lu Qiao Mufei Liu Yanpeng Ran Jun Wang Wupeng Yan Yan Feng Li Cui 
supported by the National Key Research and Development Program of China(2018YFE0200501 and 2020YFA0907700);the National Natural Science Foundation of China(32271306 and 21977067).
Sugar aminotransferases(SATs)catalyze the installation of chiral amines onto specific keto sugars,pro-ducing bioactive amino sugars.Their activity has been utilized in artificial reactions,such as using the SAT WecE t...
关键词：Sugar aminotransferase Stability-activity trade-off Combinatorial active-site saturation test Iterative saturation mutagenesis Artificial reaction Valienamine 
Functional Cure of Chronic Hepatitis B with Antiviral Treatment in Children having High-level Viremia and Normal or Mildly Elevated Serum Aminotransferase被引量：6
《Journal of Clinical and Translational Hepatology》2023年第5期1011-1022,共12页Jing Li Peiyao Fan Zhiqiang Xu Yi Dong Fuchuan Wang Weiguo Hong Jinfang Zhao Yinjie Gao Jianguo Yan Lili Cao Chao Zhang Shishu Zhu Fu-Sheng Wang Min Zhang 
supported by Innovation Groups of the National Natural Science Foundation of China(81721002);the China National Natural Science Foundation(82130019);the National Key R&D Program of China(2019YFC0840704).
Background and Aims:There is a lack of data supporting the notion that antiviral treatments can beneft children with chronic hepatitis B(CHB)having high viremia and normal or mildly elevated serum alanine aminotransfe...
关键词：Child HBV Chronic hepatitis B Antiviral therapy Functional cure 
Coronavirus Disease 2019 and Liver Injury:A Retrospective Analysis of Hospitalized Patients in New York City
《Journal of Clinical and Translational Hepatology》2021年第4期551-558,共8页Joshua M.Bender Howard J.Worman 
National Institute of Diabetes and Digestive and Kidney Disease(No.T35DK93430)to JMB and the National Center for Advancing Translational Sciences(No.UL1TR001873)of the National Institutes of Health to support the Irving Center for Clinical and Translational Research at Columbia University;The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Background and Aims:Coronavirus disease 2019(COVID-19)is a global threat,affecting more than 100 million people and causing over 2 million deaths.Liver laboratory test abnormalities are an extrapulmonary manifestation...
关键词：AMINOTRANSFERASE BILIRUBIN Ischemic hepatitis SARS-CoV-2 
Overlap of concurrent extrahepatic autoimmune diseases is associated with milder disease severity of newly diagnosed autoimmune hepatitis被引量：1
《Hepatobiliary & Pancreatic Diseases International》2021年第1期21-27,共7页Tobias Mühling Helmut Rohrbach Wolfgang Schepp Felix Gundling 
Background:Concurrent extrahepatic autoimmune disorders(CEHAID)are frequently observed in autoimmune hepatitis(AIH).It is not clear whether there is any prognostic significance of CEHAID on AIH.The aim of this study w...
关键词：Autoimmune hepatitis Concurrent extrahepatic AUTOIMMUNE disease Serum aminotransferase activities 
Role of the metabolism of branched-chain amino acids in the development of Alzheimer’s disease and other metabolic disorders被引量：12
《Neural Regeneration Research》2020年第8期1460-1470,共11页Baruh Polis Abraham O.Samson 
supported by a Marie Curie CIG Grant 322113;a Leir Foundation Grant;a Ginzburg Family Foundation Grant;a Katz Foundation Grant to AOS
Alzheimer’s disease is an incurable chronic neurodegenerative disorder and the leading cause of dementia,imposing a growing economic burden upon society.The disease progression is associated with gradual deposition o...
关键词：ARGINASE ARGININE branched-chain aminotransferase BCAAs DEMENTIA mTOR norvaline urea cycle VALINE 
Body Building and Aminotransferase Elevations:A Review被引量：3
《Journal of Clinical and Translational Hepatology》2020年第2期161-167,共7页Jaimy Villavicencio Kim George YWu 
In addition to liver injury, elevation of aminotransferases can be caused by strenuous exercise and use of muscle-building and weight-loss supplements. The purpose of this review is to discuss the various mechanisms o...
关键词：AMINOTRANSFERASES EXERCISE Weight-loss supplements Muscle-building supplements 
Tillering and small grain 1 dominates the tryptophan aminotransferase family required for local auxin biosynthesis in rice被引量：11
《Journal of Integrative Plant Biology》2020年第5期581-600,共20页Tao Guo Ke Chen Nai-Qian Dong Wang-Wei Ye Jun-Xiang Shan Hong-Xuan Lin 
supported by grants from the Ministry of Science and Technology of China(2016YFD0100902);Chinese Academy of Sciences(QYZDY-SSW-SMC023,XDB27010104);National Natural Science Foundation of China(31788103);China Postdoctoral Science Foundation(2018M642102);the Shanghai Science and Technology Development(18JC1415000);National Key Laboratory of Plant Molecular Genetics.
Auxin is a crucial phytohormone,controlling multiple aspects of plant growth and responses to the changing environment.However,the role of local auxin biosynthesis in specific developmental programs remains unknown in...
关键词：GRAIN LOCAL AUXIN 
Effects of Fuzheng Huayu Capsules combined with nucleoside antiviral drugs on liver and kidney function, serum inflammatory factors, TLR-4, TGF-β1 and aspartate aminotransferase-platelet ratio index in patients with HBV infection and decompensated liver
《Journal of Hainan Medical University》2020年第4期45-49,共5页Hai-Ling Zhang Dong-Xue Mei Shan Wang Jie Zhang Xiao-Zhong Jiang Yan-Min Zhang Bin Liu 
China Hepatitis Prevention Fund Project(No.tqgb20170015);Hebei medical science research key project(No.20170933);Hebei medical science research key project(No.20150842);Hebei Science and Technology Department funded project(No.162777133).
Objective:To investigate the effect of Fuzheng Huayu Capsule combined with nucleoside antiviral drugs on liver and kidney function,serum inflammatory factors,Toll-like receptor 4(TLR-4),transforming growth factorβ1(T...
关键词：Fuzheng Huayu Nucleoside antiviral drugs DECOMPENSATED cirrhosis ASPARTATE aminotransferase-platelet RATIO INDEX 
Liquid biopsy for non-invasive assessment of liver injury in hepatitis B patients被引量：11
《World Journal of Gastroenterology》2019年第29期3985-3995,共11页Wen-Ying Xia Li Gao Er-Hei Dai Dan Chen Er-Fu Xie Li Yang Shi-Chang Zhang Bing-Feng Zhang Jian Xu Shi-Yang Pan 
the National Natural Science Foundation of China,No.81672100 and No.81371894;the Key Laboratory for Laboratory Medicine of Jiangsu Province of China,No.ZDXKB2016005;Jiangsu Provincial Commission of Health and Family Planning,No.H201609
BACKGROUND Hepatitis B is a major public health problem in China. Accurate liver injury assessment is essential for clinical evidence-based treatment. Liver biopsy is considered the gold standard method to stage liver...
关键词：LIQUID BIOPSY plasma DNA Hepatitis B ALANINE AMINOTRANSFERASE DUPLEX real-time quantitative POLYMERASE chain reaction 
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