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Impact of Liver Functions by Repurposed Drugs for COVID-19 Treatment被引量：1: 《Journal of Clinical and Translational Hepatology》2022年第4期748-756,共9页Rongzhi Zhang Qiang Wang Jianshe Yang; This work was supported by the Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital(Grant No.CY2019-BJ07);the Gansu Natural Science Foundation(Grant No.20JR10RA745).; Liver injury is an important complication that may arise in patients suffering from coronavirus disease 2019(COV-ID-19)and is accompanied by a transient increase of transaminases and/or other liver enzymes.Liver funct...; 关键词：Liver injury HEPATOTOXICITY COVID-19 ANTIVIRALS AMINOTRANSFERASES DILI

Body Building and Aminotransferase Elevations:A Review被引量：3: 《Journal of Clinical and Translational Hepatology》2020年第2期161-167,共7页Jaimy Villavicencio Kim George YWu; In addition to liver injury, elevation of aminotransferases can be caused by strenuous exercise and use of muscle-building and weight-loss supplements. The purpose of this review is to discuss the various mechanisms o...; 关键词：AMINOTRANSFERASES EXERCISE Weight-loss supplements Muscle-building supplements

Abnormal liver function tests associated with severe rhabdomyolysis被引量：9: 《World Journal of Gastroenterology》2020年第10期1020-1028,共9页Andy KH Lim; Rhabdomyolysis is a syndrome of skeletal muscle injury with release of cellular constituents such as potassium,phosphate,urate and intracellular proteins such as myoglobin into the circulation,which may cause complica...; 关键词：RHABDOMYOLYSIS MUSCLE Creatine kinase Liver function tests Alanine aminotransferase Aspartate aminotransferase AMINOTRANSFERASES

Nonalcoholic steatohepatitis pharmacotherapy and predictors of response: dual role of aminotransferases as biosensors of metabolism and biomarkers of histological improvement: 《Hepatobiliary Surgery and Nutrition》2019年第4期381-385,共5页Silvia Sookoian Carlos J.Pirola; Agencia Nacional de Promoción Científica y;Tecnológica, Fondo para la Investigación Científica y Tecnológica (FonCyT)(PICT 2014-0432 and PICT 2015-0551 to S Sookoian and PICT 2014-1816 and 2016-0135 to CJ Pirola).; Nonalcoholic steatohepatitis (NASH)—the severe histological form of nonalcoholic fatty liver disease (NAFLD)—is regarded as a major health problem worldwide (1,2). The disease can progress to liver cirrhosis and eve...; 关键词：METABOLISM HISTOLOGICAL DRUGS

Postoperative day one serum alanine aminotransferase does not predict patient morbidity and mortality after elective liver resection in non-cirrhotic patients被引量：1: 《Hepatobiliary & Pancreatic Diseases International》2016年第6期655-659,共5页Ricky Harminder Bhogal Amit Nair Davide Papis Zaed Hamady Jawad Ahmad For Tai Lam Saboor Khan Gabriele Marangoni; ABSTRACT： Serum aminotransferases have been used as surrogate markers for liver ischemia-reperfusion injury that follows liver surgery. Some studies have suggested that rises in serum alanine aminotransferase （ALT）...; 关键词：alanine aminotransferase HEPATECTOMY reperfusion injury AMINOTRANSFERASES postoperative complications

Longitudinal Changes in Liver Aminotransferases Predict Metabolic Syndrome in Chinese Patients with Nonviral Hepatitis被引量：5: 《Biomedical and Environmental Sciences》2016年第4期254-266,共13页CHEN Qi Cai XIAO Juan ZHANG Peng Peng CHEN Li Li CHEN Xiao Xiao WANG Shu Mei; Objective This study explored the correlation of longitudinal changes in serum alanine aminotransferase （ALT） and aspartate aminotransferase （AST） levels with the incidence of metabolic syndrome （Mets） based on ...; 关键词：Alanine aminotransferase Aspartate aminotransferase Metabolic syndrome Dynamic cohortstudy Generalized estimating equation model

Liver enzymes,metabolomics and genome-wide association studies:From systems biology to the personalized medicine被引量：39: 《World Journal of Gastroenterology》2015年第3期711-725,共15页Silvia Sookoian Carlos J Pirola; Supported by(in part)Grants PICT 2010-0441 and PICT 2012-0159(Agencia Nacional de Promoción Científica y Tecnológica)and UBACYT CM04(Universidad de Buenos Aires); For several decades,serum levels of alanine(ALT) and aspartate(AST) aminotransferases have been regarded as markers of liver injury,including a wide range of etiologies from viral hepatitis to fatty liver.The increasi...; 关键词：TRANSAMINASES AMINOTRANSFERASES Alanineaminotransf

Association between nonalcoholic fatty liver disease and acute ischemic stroke severity and outcome被引量：2: 《World Journal of Hepatology》2013年第11期621-626,共6页Konstantinos Tziomalos Vasilios Giampatzis Stella D Bouziana Marianna Spanou Maria Papadopoulou Athinodoros Pavlidis Stavroula Kostaki Andreas Bozikas Christos Savopoulos Apostolos I Hatzitolios; AIM:To evaluate the association of nonalcoholic fatty liver disease(NAFLD)with acute ischemic stroke severity and in-hospital outcome.METHODS:We prospectively studied all patients who were admitted in our Department ...; 关键词：NONALCOHOLIC fatty liver DISEASE Stroke OUTCOME AMINOTRANSFERASES γ-glutamyl TRANSPEPTIDASE CARDIOVASCULAR DISEASE Type 2 diabetes mellitus Obesity CARDIOVASCULAR risk

A molecular dynamics and computational study of human KAT3 involved in KYN pathway: 《Science China Chemistry》2013年第4期514-523,共10页XU Yu ZHENG QingChuan YU LiYing ZHANG HongXing SUN ChiaChung; supported by the National Natural Science Foundation of China;Specialized Research Fund for the Doctoral Program of Higher Education;Specialized Fund for the Basic Research of Jilin University (20903045, 20573042, 20070183046,200810018); Kynurenine aminotransferases （KATs） catalyze the transamination of kynurenine （KYN） pathway and endogenous KYNs have been suggested to highly correlate to abnormal brain diseases. HKAT3 is a key member of KAT fami...; 关键词：kynurenine （KYN） kynurenine aminotransferases （KATs） ^-~ interaction molecular dynamic （MD） simulation interaction energy

Genetically confirmed Wilson disease in a 9-month old boy with elevations of aminotransferases被引量：11: 《World Journal of Hepatology》2013年第3期156-159,共4页Joo Whee Kim Jong Hyun Kim Jeong Kee Seo Jae Sung Ko Ju Young Chang Hye Ran Yang Kyung Hoon Kang; Wilson disease (WD) is an autosomal recessive disorder of copper transport caused by alteration of the adenosine triphosphatase 7B gene. It is rare to diagnose WD below the age of three years. Molecular genetic testin...; 关键词：Hepatolenticular DEGENERATION WILSON disease Early diagnosis Molecular GENETICS Mutation

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