17Α-ETHYNYLESTRADIOL

作品数：7被引量：28H指数：4
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相关领域：环境科学与工程更多>>
相关作者：梁念慈刘晓青吴铁崔燎林路生更多>>
相关机构：广东医学院重庆师范大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Wuhan University Journal of Natural Sciences》《Maternal-Fetal Medicine》《Journal of Traditional Chinese Medicine》更多>>
相关基金：国家自然科学基金中国博士后科学基金重庆市教委科研基金更多>>
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Impaired Compensatory Vasodilatory Effect Mediated by Wolfram Syndrome 1 and Corticotropin-Releasing Hormone Family Peptides in 17α-Ethynylestradiol-Induced Intrahepatic Cholestasis Pregnant Rats When Under Additional Acute Hypoxia Stress
《Maternal-Fetal Medicine》2022年第1期7-16,共10页Tingting Xu Daijuan Chen Xixi Deng Yongchi Zhan Fan Zhou Xiaodong Wang 
supported by the National Natural Science Foundation of China(Grant No.81571446);the National Natural Science Foundation for Young Scientists of China(Grant No.82001560).
Objective:To investigate the possible regulatory mechanism of corticotropin-releasing hormone(CRH),urocortin(UCN),and Wolfram syndrome 1(WFS1)in 17α-ethynylestradiol(EE)-induced intrahepatic cholestasis pregnant rats...
关键词：Cholestasis intrahepatic Pregnancy Compensatory vasodilatory effect WFS1 CRH family peptides Ischemiareperfusion 
Calculus Bovis Sativus up-regulates hepatic protein 2(Mrp2) and Mrp4 in 17α-ethynylestradiol-induced cholestasis via a regulatory effect on ER signaling被引量：3
《Journal of Traditional Chinese Medicine》2019年第3期402-409,共8页Wu Tao Liu Dong Song Hongping 
Supported by the National Natural Science Foundation of China(Study of the Role and Mechanism of PDZK1 Protein in the Downregulation of Mrp2 by Estrogen in Cholestasis,No.81503146 and Study of the Choleretic Effect of Calculus Bovis Sativus Based on PDZK1 Protein Interaction Networks and Bile Acid Metabolic Profile,No.81573788);Science Foundations of Health and Family Planning Commission of Wuhan Municipality(No.WZ15Z02)
OBJECTIVE:To investigate the pathway through which Calculus Bovis Sativus (CBS) up-regulates hepatic multidrug resistance-associated protein 2 (Mrp2) and Mrp4 in 17α-ethynylestradiol (EE)-induced cholestasis.METHODS:...
关键词：Calculus BOVIS ETHYNYLESTRADIOL Receptors estrogen MULTIDRUG resistance-associated proteins ICI182780 
Pharmacokinetic Characteristics of Baicalin in Rats with 17α-ethynylestradiol-induced Intrahepatic Cholestasis被引量：6
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2018年第1期167-173,共7页Cheng-liang ZHANG Yan-jiao XU Dong XIANG Jin-yu YANG Kai LEI Dong LIU 
supported by the National Natural Science Foundation of China(No.81573788 and No.81670521)
Baicalin is one of the main active ingredients of choleretic traditional Chinese medicine drug Radix Scutellariae.The aim of this study was to explore the pharmacokinetic characteristics of baicalin in rats with 17α-...
关键词：intrahepatic cholestasis BAICALIN 17α-ehynylestradiol PHARMACOKINETICS 
17α-Ethynylestradiol biodegradation in different river-based groundwater recharge modes with reclaimed water and degradation-associated community structure of bacteria and archaea被引量：5
《Journal of Environmental Sciences》2018年第2期51-61,共11页Weifang Ma Jiaji Sun Yangyao Li Xiaoxiu Lun Dan Shan Chao Nie Miaomiao Liu 
supported by Beijing Municipal Science and Technology Commission(No.D161100000216002);the National Natural Science Foundation of China(No.51678052)
This study investigated 17α-ethynylestradiol（EE2） biodegradation process and primary metabolic pathways associated with community structures of microorganism during groundwater recharge using reclaimed water. The a...
关键词：EE2 BIODEGRADATION Groundwater recharge Microbial community and diversity Metabolic intermediates 
Photodegradation of 17α-ethynylestradiol in dissolved humic substances solution：Kinetics,mechanism and estrogenicity variation被引量：9
《Journal of Environmental Sciences》2017年第4期196-205,共10页Dong Ren Bin Huang Dan Xiong Huan He Xiangqi Meng Xuejun Pan 
sponsored by the National Natural Science Foundation of China(No.41401558);the Application Fundamental Key Basic Research Foundation of Yunnan Province,China(No.2013FA011);the Education Department Science Research Foundation of Yunnan Province,China(No.2014J022);the China Postdoctoral Science Foundation(No.2014T70887)
17α-Ethynylestradiol（EE2） in natural waters may cause adverse effects on organisms due to its high estrogenic potency. Laboratory studies were performed to study the effects of a local humic acid（LHA）, fulvic aci...
关键词：17α-Ethynylestradiol Photodegradation Dissolved humic substances Reactive oxygen species Estrogenic potency 
Photodegradation of 17α-Ethynylestradiol in Aqueous Solution with Nitzschiahantzschiana or Chlorella vulgaris and Fe^(3+)被引量：2
《Wuhan University Journal of Natural Sciences》2004年第1期109-114,共6页LiuXian-li WuFeng LiaoZhen-huan LiShun-xing DengNan-sheng 
SupportedbytheScientificResearchFoundationofWuhanEnvironmentalProtec tionBureauandtheNationalNaturalScienceFoundationofChina(2 0 1 770 1 7)
The photodegradation of 17α-ethynylestradiol (EE2) induced by highpressure mercury lamp (λ≥313 nm, 250 W) in aqueous solution with algae (e. g.Nitzschia hantzschiana andChlorella vulgaris) and Fe3+ was ineestigated...
关键词：17Α-ETHYNYLESTRADIOL PHOTODEGRADATION high-pressure mercury lamp Nitzschia hantzschiana Chlorella vulgaris FE3+ 
Preventive effects of ginsenosides on osteopenia of rats induced by ovariectomy被引量：4
《Acta Pharmacologica Sinica》2001年第5期48-54,共7页崔燎 吴铁 刘晓青 李青南 林路生 梁念慈 
AIM: To determine the effect of ginsenosides (GSL) on ovariectomized rats by analysis of cancellous bone histo-morphometry. METHODS: Forty Sprague-Dawley female rats at age of 3 months were sham-operated (Sham, n =8) ...
关键词：ginseng 17Α-ETHYNYLESTRADIOL OVARIECTOMY bone and bones OSTEOCLASTS developmental bone diseases HISTOCYTOCHEMISTRY 
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