云南高校图书馆联盟文献共享服务平台- PROMOTES

PROMOTES: 作品数：1597被引量：4595H指数：22; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：吴东明陈伟俞春东刘洋王许杰更多>>; 相关机构：北京大学中国科学院中山大学第二军医大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>

Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons: 《Neural Regeneration Research》2025年第6期1816-1824,共9页Jiantao Cui Yueru Shen Zheng Song Dinggang Fan Bing Hu; supported by the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM,No.QYZD20220002;the National Natural Science Foundation of China,No.82071357;a grant from the Ministry of Science and Technology of China,No.2019YFA0405600 (all to BH)。; Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles an...; 关键词：axonal regeneration Mauthner cell nerve regeneration Rab5 ZEBRAFISH

Isoleucyl-tRNA synthetase 2 promotespancreatic ductal adenocarcinomaproliferation and metastasis by stabilizingb-catenin: 《Genes & Diseases》2025年第3期478-491,共14页Yixun Jin Xinyang Huang Zhuoxin Wang Berik Kouken Qi Wang Lifu Wang; supported by the National Natural Science Foundation of China(No.81870385,81702740).; Isoleucyl-tRNA synthetase 2(IARS2),originally regarded as an enzyme ligatingisoleucine to the corresponding tRNA,has been identified as an oncogene recently.However,its function in pancreatic ductal adenocarcinoma(PDA...; 关键词：Aminoacyl-tRNA synthetases Isoleucyl-tRNA synthetase 2 Pancreatic ductal adenocarcinoma WNT signaling pathway b-Catenin

Foliar-applied zinc promotes cadmium allocation from leaf surfaces to grains in rice: 《Journal of Environmental Sciences》2025年第5期582-593,共12页Ya-Ting Liu Bo-Fang Yan Xuan Cai Hong-Xiang Zheng Rong-Liang Qiu Ye-Tao Tang; supported by Guangdong Basic and the Applied Basic Research Foundation(No.2022A1515011403);the Science and Technology Program of Guangdong Province(No.2022A0505090002);the National Natural Science Foundation of China(Nos.U23A2039 and 42007331);the Research Fund Program of Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology(No.2023B1212060016).; The accumulation of Cd by rice poses significant health risks.Foliar fertilizationwith Zn can reduce grain Cd contents in rice grown in Cd-contaminated soils.However,atmospheric deposition on leaves is another vector ...; 关键词：Atmospheric deposition Isotope labelling Metal interaction PHLOEM Cell wall

Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT: 《Oncology Research》2025年第5期1121-1133,共13页WENYING ZHENG YANYAN SHANG KAI DU AILING LUO LIJUN PEI MEIQI LI GUOPING ZHANG MIN DENG; supported by the National Natural Science Foundation of China(Nos.81972771,82173062);the Key Areas Project of Education Department of Guangdong Province(No.2021ZDZX2017);the Tertiary Education Scientific Research Project of Guangzhou Municipal Education Bureau(No.202235387);the Guangzhou Science and Technology Project of Guangzhou Municipal Science and Technology Bureau(No.2023A03J0428);the Natural Science Foundation of Guangdong Province,China(No.2024A1515013082);the Guangdong Basic and Applied Basic Research 21 Foundation(No.2021A1515010403).; Background:Alterations in splicing factors contribute to aberrant alternative splicing(AS),which subsequently promotes tumor progression.The splicing factor polypyrimidine tract binding protein 1(PTBP1)has been shown ...; 关键词：Hepatocellular carcinoma Alternative splicing PTBP1 MAPT

OTUB2 promotes proliferation and metastasis of triple-negative breast cancer by deubiquitinating TRAF6: 《Oncology Research》2025年第5期1135-1147,共13页YU QIU RUIHAN LIU SHANSHAN HUANG QIAOTING CAI YI XIE ZHITING HE WEIGE TAN XINHUA XIE; supported by the National Natural Science Foundation of China(No.82373380,Xinhua Xie).; Objectives:Deubiquitinase OTUB2 plays a critical role in the progression of various tumors.However,its specific role in triple-negative breast cancer(TNBC)remains unclear.This study aims to elucidate the biological fu...; 关键词：OTUB2 Tumor necrosis factor receptor-associated factor 6(TRAF6) Triple-Negative Breast Cancer(TNBC) DEUBIQUITINATION

MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits: 《Neural Regeneration Research》2025年第5期1431-1444,共14页Yuehua Cui Xiaokuang Ma Jing Wei Chang Chen Neha Shakir Hitesch Guirram Zhiyu Dai Trent Anderson Deveroux Ferguson Shenfeng Qiu; supported by NIH/NIMH grant R01MH111619(to SQ),R21AG078700(to SQ);Institute of Mental Health Research(IMHR,Level 1 funding,to SQ and DF);institution startup fund from The University of Arizona(to SQ)。; Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse functi...; 关键词：aging circuit connectivity cortical circuits molecular mechanisms neural regeneration NEURODEGENERATION synapses

A molecular module with Phe IAA17 as the core significantly promotes lateral root germination: 《Horticultural Plant Journal》2025年第2期921-934,共14页Junlei Xu Miaomiao Cai Yali Xiea Zhanchao Cheng Chongyang Wu Jian Gao; supported by the National Key Research and Development Program of China(2021YFD2200505);the National Natural Science Foundation of China(32071849)。; Monocot root systems comprise a large number of lateral roots to allow them to survive and colonize land.Auxin signaling pathways centered on Aux/IAA play a crucial role in lateral root development.However,in non-mode...; 关键词：Phyllostachys edulis Moso bamboo Lateral root PheIAA17 Auxin signaling Molecular module Class B ARF

BEND6 promotes RNA viruses'replication by inhibiting innate immune responses: 《Science China(Life Sciences)》2025年第4期1073-1083,共11页Tong Chen Ling Ding Shaoyu Tu Huimin Sun Jiahui Zou Aotian Ouyang Meijun Jiang Yi Feng Meilin Jin Huanchun Chen Hongbo Zhou; supported by the National Key Research and Development Program of China(2021YFD1800204);the National Natural Science Foundation of China(32025036);the Fundamental Research Funds for the Central Universities(2662023PY005);Hubei Hongshan Laboratory(2022hszd005);the earmarked fund for CARS-41;the Natural Science Foundation of Hubei Province(2021CFA016)。; Innate immunity serves as a crucial defense mechanism against invading pathogens,yet its negative regulatory network remains under explored.In this study,we identify BEN domain-containing protein 6(BEND6)as a novel ne...; 关键词：innate immunity BEND6 RNAvirus IRF3 IFN-Β

TMEM33,an oncogene regulated by miR-214-3p,promotes the progression of lung adenocarcinoma through the Wnt/β-catenin signaling pathway: 《Oncology Research》2025年第4期905-917,共13页GUANGXIAN YOU QIAO YANG XIN LI LILI CHEN; Background:Lung cancer remains a major factor causing cancer-associated mortality globally.While there have been advancements in treatment options,advanced lung cancer patients still have poor outcomes.This study aims...; 关键词：Lung adenocarcinoma(LUAD) Transmembrane protein 33(TMEM33) miR-214-3p Wingless(Wnt) Malignant progression

NOP56 promotes hepatocellular carcinoma progression through 2'-O-methylation: 《Genes & Diseases》2025年第2期33-36,共4页Shuxin Yang Juan Liu Shengxin Luo Wentao Wang Jingxiang Xu; funded by the High-level Talent Research Funds of Gannan Medical University (No.QD202122).; Hepatocellular carcinoma(HCC)is a common malignant tumor and one of the leading causes of cancer-related deaths,with the fourth-highest incidence rate and the second-highest mortality rate in China.1 Currently,HCC is ...; 关键词：MORTALITY CHEMOTHERAPY surgery

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