THIOGUANINE

作品数：5被引量：8H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Science China Chemistry》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》《Progress in Natural Science:Materials International》更多>>
相关基金：国家自然科学基金更多>>
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Copper-thioguanine metallodrug with self-reinforcing circular catalysis for activatable MRI imaging and amplifying specificity of cancer therapy
《Science China Chemistry》2020年第7期924-935,共12页Haifeng Yuan Yan Zhao Chan Yang Cheng Zhang Yue Yang Hongmin Meng Shuangyan Huan Guosheng Song Xiaobing Zhang 
supported by the National Natural Science Foundation of China (51872088, 21977027, 21804039, 21675043, 21890744)。
For chemotherapy, drug delivery systems often suffer from the inefficient drug loading capability, which usually cause systems toxicity and extra burden to excrete carrier itself. Moreover, the cancer therapeutic effi...
关键词：coordination nanoplatform metallodrug chemodynamic therapy circular catalysis drug delivery 
Efficacy of thioguanine treatment in inflammatory bowel disease: A systematic review被引量：5
《World Journal of Gastroenterology》2016年第40期9012-9021,共10页Berrie Meijer Chris JJ Mulder Godefridus J Peters Adriaan A van Bodegraven Nanne KH de Boer 
AIM To critically assess the available literature regarding the efficacy of thioguanine treatment in inflammatory bowel disease(IBD) patients, irrespective of the(hepato-) toxicity profile.METHODS A systematic literat...
关键词：THIOPURINES THIOGUANINE Inflammatory bowel disease Crohn’s disease Ulcerative colitis 
How I treat my inflammatory bowel disease-patients with thiopurines?被引量：1
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2016年第4期524-530,共7页Berrie Meijer Chris JJ Mulder Adriaan A van Bodegraven Nanne KH de Boer 
Thiopurines are essential drugs to maintain remission in patients with inflammatory bowel disease(IBD).Thiopurines used in IBD are azathioprine(2.0-2.5 mg/kg),mercaptopurine(1.0-1.5 mg/kg) and thioguanine(0.2-0.3 mg/k...
关键词：THIOPURINES AZATHIOPRINE MERCAPTOPURINE THIOGUANINE Inflammatory bowel disease Therapeutic drug monitoring Pregnancy METABOLITES 
Therapeutic drug monitoring in patients with inflammatory bowel disease被引量：2
《World Journal of Gastroenterology》2014年第13期3475-3484,共10页Andres J Yarur Maria T Abreu Amar R Deshpande David H Kerman Daniel A Sussman 
Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do no...
关键词：Inflammatory bowel disease Anti-tumor necrosis factor INFLIXIMAB ADALIMUMAB Drug level AZATHIOPRINE THIOPURINES ANTIBODIES Drug monitoring THIOGUANINE 
Thiobase DNA: the chemistry and some applications in cancer studies
《Progress in Natural Science:Materials International》2000年第6期3-15,共13页徐耀忠 
This article reviews the chemical methods for preparation of base-modified DNA with a particular focus on thiobases. Thiobases have certain unique properties, such as easy alkylation, ready oxidation and strong absorp...
关键词：THIOGUANINE modified BASE DNA REPAIR chemical synthesis. 
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