云南高校图书馆联盟文献共享服务平台- MERCAPTOPURINE

MERCAPTOPURINE: 作品数：14被引量：27H指数：3; 导出分析报告; 相关领域：医药卫生化学工程更多>>; 相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》《Gastroenterology Report》更多>>; 相关基金：湖北省自然科学基金国家自然科学基金更多>>

Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease被引量：1: 《World Journal of Gastroenterology》2017年第18期3240-3251,共12页James D Lord Donna M Shows; Supported by Virginia Mason Medical Center,Digestive Disease Institute Research Grant Award,No.0506812-2011; To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo.METHODSThe thiopurines azathioprine and 6-mercaptopurine have been a mainstay of inflammatory bowel diseas...; 关键词：THIOPURINE AZATHIOPRINE MERCAPTOPURINE LYMPHOCYTE Natural killer cell Transitional B cell Inflammatory bowel disease

Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective被引量：3: 《World Journal of Gastroenterology》2016年第46期10103-10117,共15页Jordan E Axelrad Abhik Roy Garrett Lawlor Burton Korelitz Simon Lichtiger; The use of thiopurines in inflammatory bowel disease(IBD) has been examined in numerous prospective, controlled trials, with a majority demonstrating a clinical benefit. We conducted this review to describe the histor...; 关键词：Inflammatory bowel disease Ulcerative colitis Crohn’s disease THIOPURINES MERCAPTOPURINE AZATHIOPRINE

How I treat my inflammatory bowel disease-patients with thiopurines?被引量：1: 《World Journal of Gastrointestinal Pharmacology and Therapeutics》2016年第4期524-530,共7页Berrie Meijer Chris JJ Mulder Adriaan A van Bodegraven Nanne KH de Boer; Thiopurines are essential drugs to maintain remission in patients with inflammatory bowel disease(IBD).Thiopurines used in IBD are azathioprine(2.0-2.5 mg/kg),mercaptopurine(1.0-1.5 mg/kg) and thioguanine(0.2-0.3 mg/k...; 关键词：THIOPURINES AZATHIOPRINE MERCAPTOPURINE THIOGUANINE Inflammatory bowel disease Therapeutic drug monitoring Pregnancy METABOLITES

A case of cerebral venous sinus thrombosis associated with Crohn’s disease:dilemma in management: 《Gastroenterology Report》2016年第2期154-157,I0003,共5页Younghoon Kwon Ryan J Koene Yeilim Cho; The authors would like to thank Thinesh Sivapatham,MD and Michael T.Madison,MD of Saint Paul Radiology for reviewing the images enclosed in this manuscript.; Inflammatory bowel disease(IBD)is known to increase the risk of venous thromboembolism.Cerebral venous sinus thrombosis(CVST)is a rare but important complication of IBD.Timely diagnosis,particularly in younger patient...; 关键词：cerebral venous sinus thrombosis Crohn’s disease ANTICOAGULATION MERCAPTOPURINE WARFARIN

Clinical predictors of thiopurine-related adverse events in Crohn's disease被引量：2: 《World Journal of Gastroenterology》2015年第25期7795-7804,共10页Gordon W Moran Marie-France Dubeau Gilaad G Kaplan Hong Yang Bertus Eksteen Subrata Ghosh Remo Panaccione; the Alberta Inflammatory Bowel Disease Consortium and the Alberta Innovates Health Solutions for funding support for this project; AIM: To determine the incidence and predictors of thiopurine-related adverse events. METHODS: Subjects with Crohn's disease who were followed in the Alberta Inflammatory Bowel Disease Consortium patient database regis...; 关键词：THIOPURINES AZATHIOPRINE MERCAPTOPURINE ADVERSE EVENTS

Routine use of thiopurines in maintaining remission in pediatric Crohn's disease: 《World Journal of Gastroenterology》2014年第27期9185-9190,共6页Brendan M Boyle Michael D Kappelman Richard B Colletti Robert N Baldassano David E Milov Wallace V Crandall; AIM: To evaluate the effectiveness of thiopurines in maintaining steroid-free remission in routine clinical practice.; 关键词：Crohn's disease PEDIATRIC REMISSION THIOPURINES MERCAPTOPURINE

Use of thiopurines in inflammatory bowel disease: Safety issues被引量：3: 《World Journal of Gastrointestinal Pharmacology and Therapeutics》2014年第2期63-76,共14页Anastasia Konidari Wael El Matary; Thiopurines are widely used for maintenance treatment of inflammatory bowel disease. Interindividual variability in clinical response to thiopurines may be attributed to several factors including genetic polymorphisms...; 关键词：THIOPURINES AZATHIOPRINE MERCAPTOPURINE INFLAMMATORY BOWEL disease Adult Children THERAPEUTIC drug monitoring

Preparation and in vitro Release Properties of Mercaptopurine Drug-loaded Magnetic Microspheres被引量：2: 《Journal of Wuhan University of Technology(Materials Science)》2013年第6期1231-1235,共5页XU Haixing ZHANG Yu NIU Xiaoqian WANG Ling CHEN Hui ZHANG Xi TANG Qiuhan HUANG Zhijun LIU Hui XU Peihu; Funded by the Natural Science Foundation of Hubei Province(No.2011CDA056);the International Cooperation Funding of Hubei Province(No.2012IHA0120);the Fundamental Research Funds for the Central Universities of China(2012-IV-029);the Undergraduate innovation Funding of Wuhan University of Technology(136620004); Magnetic Fe304 nanoparticles were synthesized by co-precipitation method and the mercaptopurine （MER） drug-loaded magnetic microspheres were obtained through emulsion cross-linking methods. The efficiency of this ap...; 关键词：MERCAPTOPURINE magnetic microspheres drug loading content encapsulation efficiency

Thiopurines related malignancies in inflammatory bowel disease:Local experience in Granada,Spain被引量：1: 《World Journal of Gastroenterology》2013年第30期4877-4886,共10页María Gómez-García Maria José Cabello-Tapia Antonio Damián Sánchez-Capilla Javier De Teresa-Galván Eduardo Redondo-Cerezo; AIM:To investigate the incidence of neoplasms in inflammatory bowel disease(IBD)patients and the potential causative role of thiopurines.METHODS:We performed an observational descriptive study comparing the incidence ...; 关键词：Malignancy Neoplasm Inflammatory bowel DISEASE Crohn’s DISEASE ULCERATIVE colitis THIOPURINES AZATHIOPRINE MERCAPTOPURINE

Thiopurines in inflammatory bowel disease revisited被引量：5: 《World Journal of Gastroenterology》2013年第11期1699-1706,共8页Florian Br Christian Sina Klaus Fellermann; Although a great variety of new drugs have been introduced for the therapy of inflammatory bowel diseases so far,a definite cure of the disease is still out of scope.An anti-inflammatory approach to induce remission f...; 关键词：THIOPURINES MERCAPTOPURINE Tioguanine AZATHIOPRINE ULCERATIVE COLITIS Crohn’s DISEASE

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