MACROAUTOPHAGY

作品数：19被引量：417H指数：7
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相关领域：生物学更多>>
相关机构：东北林业大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Frontiers in Biology》《World Journal of Gastroenterology》《Genes & Diseases》更多>>
相关基金：国家自然科学基金重庆市自然科学基金上海市自然科学基金上海市青年科技启明星计划更多>>
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Autophagy-lysosome pathway as a source of candidate biomarkers for Parkinson's disease
《Neuroimmunology and Neuroinflammation》2021年第2期101-110,共10页Nikolaos Papagiannakis Leonidas Stefanis 
Parkinson's disease(PD)is a neurodegenerative disorder characterized by progressive motor disturbances and affects more than 1%of the worldwide population.Diagnosis of PD relies on clinical history and physical examin...
关键词：MACROAUTOPHAGY chaperone-mediated autophagy SYNUCLEINOPATHY Lewy bodies Gaucher disease GLUCOCEREBROSIDASE Hsc70 
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy被引量：13
《Translational Neurodegeneration》2019年第1期215-229,共15页Jia-Zhen Wu Mustafa Ardah Caroline Haikal Alexander Svanbergsson Meike Diepenbroek Nishant N.Vaikath Wen Li Zhan-You Wang Tiago F.Outeiro Omar M.El-Agnaf Jia-Yi Li 
We would like to acknowledge financial supports by the National Natural Science Foundation(81430025,81701265,31800898,U801681);Acknowledgements are also to the supports of the Swedish Research Council(K2015-61X-22297-03-4);EU-JPND(aSynProtec),EU-JPND(REfrAME),EU H2020-MSCA-ITN-2016(Syndegen),BAGADILICO-Excellence in Parkinson and Huntington Research,the Strong Research Environment MultiPark(Multidisciplinary research on Parkinson’s disease),the Swedish Parkinson Foundation(Parkinsonfonden),Torsten Söderbergs Foundation,Olle Engkvist Byggmästere Foundation;W.L.is supported by a scholarship from the China Scholarship Council;TFO is supported by the DFG Center for Nanoscaly Microscopy and Molecular Physiology of the Brain(CNMPB).
Background:Progressive accumulation ofα-synuclein is a key step in the pathological development of Parkinson’s disease.Impaired protein degradation and increased levels ofα-synuclein may trigger a pathological aggr...
关键词：chaperone-mediated autophagy MACROAUTOPHAGY ALPHA-SYNUCLEIN protein aggregation Parkinson disease lysosomal-associated membrane protein 
Dysregulation of autophagy and mitochondrial function in Parkinson’s disease被引量：7
《Translational Neurodegeneration》2016年第1期152-160,共9页Bao Wang Neeta Abraham Guodong Gao Qian Yang 
The works were supported by National Natural Science Foundation of China(Grant No.31371400)(Q.Y)and(Grant No.31671060)(Q.Y).
Parkinson’s disease(PD)is the second most common neurodegenerative disease.Increasing evidence supports that dysregulation of autophagy and mitochondrial function are closely related with PD pathogenesis.In this revi...
关键词：Parkinson’s disease AUTOPHAGY MACROAUTOPHAGY MITOPHAGY Chaperone-mediated autophagy Mitochondria α-synuclein PINK/Parkin LRRK2 DJ-1 
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