ANTITHROMBOTIC

作品数:42被引量:131H指数:6
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相关作者:史薇薇王生高品一李玲芝宋少江更多>>
相关机构:中国药科大学首都医科大学沈阳药科大学更多>>
相关期刊:《World Journal of Clinical Cases》《沈阳药科大学学报》《Bioactive Materials》《China Medical Abstracts(Internal Medicine)》更多>>
相关基金:国家自然科学基金国家教育部博士点基金更多>>
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Design and performance of double-layered artificial chordae
《Regenerative Biomaterials》2025年第1期113-125,共13页Tingchao Zhang Yichen Dou Yang Li Rifang Luo Li Yang Weiwei Zhang Yunbing Wang Xingdong Zhang 
supported by National Key Research and Development Program 2022YFC2409100;Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences[CIFMS,(no.2021-I2M-5-013)];111 Project[The Program of Introducing Talents of Discipline to Universities(no.B16033)].
Surgical repair with artificial chordae replacement has emerged asa standard treatment for mitral regurgitation. Expanded polytetrafluoroethylene (ePTFE) sutures are commonly employed asartificial chordae;however, the...
关键词:artificial chordae double-layered artificial chordae EPTFE UHMWPE ANTITHROMBOTIC enhanced fatigue resistance 
Pharmacological effects of bioactive agents in earthworm extract:A comprehensive review
《Animal Models and Experimental Medicine》2024年第5期653-672,共20页Zihan Zhu Xinyi Deng Wenqing Xie Hengzhen Li Yusheng Li Zhenhan Deng 
supported by the National Key R&D Program of China(2021YFC2502100,2023YFC3603404,2019YFA0111900);National Natural Science Foundation of China(82072506,82272611,92268115);Hunan Provincial Science Fund for Distinguished Young Scholars(2024JJ2089);Hunan Young Talents of Science and Technology(2021RC3025);Provincial Clinical Medical Technology Innovation Project of Hunan(2023SK2024,2020SK53709);Provincial Natural Science Foundation of Hunan(2020JJ3060);National Natural Science Foundation of Hunan Province(2023JJ30949);National Clinical Research Center for Geriatric Disorders,Xiangya Hospital(2021KFJJ02,2021LNJJ05);the Hunan Provincial Innovation Foundation for Postgraduate(CX20230308,CX20230312);the Independent Exploration and Innovation Project for Postgraduate Students of Central South University(2024ZZTS0163)。
This review compiles information from the literature on the chemical composition,pharmacological effects,and molecular mechanisms of earthworm extract(EE)and suggests possibilities for clinical translation of EE.We al...
关键词:ANTITHROMBOTIC ANTITUMOR bioactive agent earthworm extract pharmacological effects 
Antibiofilm and antithrombotic hydrogel coating based on superhydrophilic zwitterionic carboxymethyl chitosan for blood-contacting devices被引量:1
《Bioactive Materials》2024年第4期112-124,共13页Dong Uk Lee Mukhammad Kayumov Junghun Park Se Kye Park Yeongkwon Kang Yejin Ahn Woojin Kim Seung Hwa Yoo Jun-Kyu Park Bong-Gi Kim Yong Suk Oh In-Seok Jeong Dong Yun Choi 
supported by the Korea Evaluation Institute of Industrial Technology(KEIT)grant funded by the South Korea government(MOTIE)(No.1415187426,RS-2023-00238181);supported by the institutional program funded by the Korea Institute of Industrial Technology(JA230007);the National Research Foundation of Korea(NRF)grant funded by the South Korea government(MSIT)(No.2022R1F1A1074255,No.RS-2022-00144435).
Blood-contacting devices must be designed to minimize the risk of bloodstream-associated infections,thrombosis,and intimal lesions caused by surface friction.However,achieving effective prevention of both bloodstream-...
关键词:ZWITTERIONIC Hydrogel Blood-clotting Antimicrobial Sepsis 
Is medical management useful in Moyamoya disease?被引量:1
《World Journal of Clinical Cases》2024年第3期466-473,共8页Sombat Muengtaweepongsa Vatcharasorn Panpattanakul 
Moyamoya disease(MMD),characterized by progressive internal carotid artery stenosis and collateral vessel formation,prompts cerebral perfusion complications and is stratified into idiopathic and Moyamoya syndrome subt...
关键词:Moyamoya disease Cerebral infarction Antithrombotic management Transcranial doppler REVASCULARIZATION Intracerebral hemorrhage Antihypertensive intervention Lipid-lowering therapies 
Structural characteristics,anticoagulant and antithrombotic mechanism of a novel polysaccharide from Rosa Chinensis Flos被引量:6
《Food Science and Human Wellness》2023年第2期407-415,共9页Xiaofeng Zhang Zhenhua Liang Geoffrey Ivan Neil Waterhouse Shengjun Jiang Dongxiao Sun-Waterhouse Jinmei Wang Changyang Ma Wenyi Kang 
supported by Research on Precision Nutrition and Health Food,Department of Science and Technology of Henan Province(CXJD2021006);Key Project in Science and Technology Agency of Henan Province(202102110283 and 202102110149)。
This is the first report on a polysaccharide(RCJ2-Ib)isolated from Rosa Chinensis Flos.RCJ2-Ib was obtained through the extraction with water,precipitation with ethanol,separation with DEAE-52 column and purification ...
关键词:Rosa Chinensis Flos Polysaccharide isolation Antithrombotic activity Intestinal flora 
An update on the management of non-variceal upper gastrointestinal bleeding被引量:6
《Gastroenterology Report》2023年第1期60-77,共18页Ali A.Alali Alan N.Barkun 
Upper gastrointestinal bleeding(UGIB)continues to be a common gastrointestinal emergency that carries significant morbidity and mortality.The epidemiology of UGIB has been changing over the last few decades with an ov...
关键词:UGIB peptic ulcer endoscopic hemostasis risk assessment ANTITHROMBOTIC 
Antithrombotic therapy and bleeding risk in the era of aggressive lipid-lowering:current evidence,clinical implications,and future perspectives被引量:1
《Chinese Medical Journal》2023年第6期645-652,共8页Xin Zhou Ziping Li Hangkuan Liu Yongle Li Dong Zhao Qing Yang 
National Key Research and Experimental Development Program of China(Nos.2020YFC2004700 and 2020YFC2004706);the National Natural Science Foundation of China(No.81970304);the Tianjin Municipal Science and Technology Commission(No.18ZXZNSY00290)
The clinical efficacy of proprotein convertase subtilisin/kexin type 9 inhibitors(PCSK9i)in reducing major cardiovascular adverse events related to atherosclerotic cardiovascular disease(ASCVD)has been well establishe...
关键词:Cholesterol-lowering drugs BLEEDING ANTITHROMBOTIC LDL cholesterol Proprotein convertase subtilisin/kexin type 9 inhibitors 
Nitric oxide-generating self-assembling peptide hydrogel coating for enhancing hemocompatibility of blood-contacting devices被引量:1
《Journal of Materials Science & Technology》2022年第36期106-114,共9页Hao Li Qianru Guo Qiufen Tu Kaiqin Xiong Wei Wang Lei Lu Wentai Zhang Nan Huang Zhilu Yang 
financially supported by the National Natural Science Foundation of China(Nos.82072072,32171326 and 31800795);the International Cooperation Project by the Science and Technology Department of Sichuan Province(No.2021YFH0056);the Sichuan Science and Technology Program(No.2021JDRC0160);the High-level Talents Research and Development Program of Affiliated Dongguan Hospital(No.K202102)。
Thrombosis is the major stumbling block to the clinical application of blood-contacting devices.Herein,a quick and easy surface engineering strategy of hydrogel coating with the therapeutic gas nitric oxide(NO)generat...
关键词:Blood-contacting device NO generation Self-assembling peptide Hydrogel coating Antithrombotic ability 
Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study
《Journal of Geriatric Cardiology》2022年第5期354-366,共13页Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado 
The study was funded by an unrestricted grant from Abbott Laboratories(COR10620).
OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antith...
关键词:patients BLEEDING ANTITHROMBOTIC 
Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report被引量:2
《World Journal of Clinical Cases》2022年第12期3936-3943,共8页Rui-Feng Liu Xiang-Yu Gao Si-Wen Liang Hui-Qiang Zhao 
Supported by National Natural Science Foundation of China,No. 81600276
BACKGROUND There is no consensus on the antithrombotic treatment strategy for patients with coronary artery ectasia(CAE).CASE SUMMARY This case reports the dynamic observation of a patient for 48 mo after a diagnosis ...
关键词:Coronary artery ectasia Acute myocardial infarction Antithrombotic agents Anti-thrombosis agents Case report 
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