supported by the National Natural Science Foundation of China (Nos. 82173884, 82204511, and 82073922);the Jiangsu Funding Program for Excellent Postdoctoral Talent (No. 1412200067, China);the “Double First-Class” university project (No. CPU2022QZ21, China)。
Type 2 diabetes(T2D) is often accompanied with an induction of retinaldehyde dehydrogenase 1(RALDH1 or ALDH1A1) expression and a consequent decrease in hepatic retinaldehyde(Rald)levels. However, the role of hepatic R...
Using mice that lack retinaldehyde dehydrogenase 1 gene(Raldh1-/-mice),Kierfer et al demonstrated that retinoids(metabolites of Vitamin A) play an important role in the regulation of cellular metabolisms and energetic...