GLUCOSE-6-PHOSPHATASE

作品数：8被引量：52H指数：3
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Hepatic retinaldehyde deficiency is involved in diabetes deterioration by enhancing PCK1-and G6PC-mediated gluconeogenesis被引量：2
《Acta Pharmaceutica Sinica B》2023年第9期3728-3743,共16页Hanyu Yang Mengxiang Su Ming Liu Yun Sheng Liang Zhu Lu Yang Ruijing Mu Jianjun Zou Xiaodong Liu Li Liu 
supported by the National Natural Science Foundation of China (Nos. 82173884, 82204511, and 82073922);the Jiangsu Funding Program for Excellent Postdoctoral Talent (No. 1412200067, China);the “Double First-Class” university project (No. CPU2022QZ21, China)。
Type 2 diabetes(T2D) is often accompanied with an induction of retinaldehyde dehydrogenase 1(RALDH1 or ALDH1A1) expression and a consequent decrease in hepatic retinaldehyde(Rald)levels. However, the role of hepatic R...
关键词：Type 2 diabetes RETINALDEHYDE Retinaldehyde dehydrogenase 1 GLUCONEOGENESIS Retinoid X receptor Oleic acid GLUCOSE-6-PHOSPHATASE Phosphoenolpyruvate carboxykinase 1 
Recent development and gene therapy for glycogen storage disease type Ia被引量：3
《Liver Research》2017年第3期174-180,共7页Janice Y.Chou Goo-Young Kim Jun-Ho Cho 
This research was supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development,National Institutes of Health(HD000912-38).
Glycogen storage disease type Ia(GSD-Ia)is an autosomal recessive metabolic disorder caused by a deficiency in glucose-6-phosphatase-α(G6Pase-αor G6PC)that is expressed primarily in the liver,kidney,and intestine.G6...
关键词：Glycogen storage disease type Ia(GSD-Ia) Glucose-6-phosphatase-α(G6Pase-αor G6PC) Gene therapy Hepatocellular adenoma Recombinant adeno-associated virus vector 
Sapium ellipticum(Hochst) Pax ethanol leaf extract modulates glucokinase and glucose-6-phosphatase activities in streptozotocin induced diabetic rats被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2017年第6期544-548,共5页Osasenaga Macdonald Ighodaro Oluseyi Adeboye Akinloye Regina Ngozi Ugbaja Samuel Olatunbosun Omotainse 
Objective:To examine the effects of Sapium ellipticum(SE) leaf extract on the hepatic activities of glucokinase and glucose-6-phosphatase in streptozotocin-induced diabetic Wistar rats.Methods:STZ-induced diabetic Wis...
关键词：Sapium ellipticum Glucose homeostasis DIABETES GLUCOKINASE GLUCOSE-6-PHOSPHATASE 
Sapium ellipticum (Hochst) Pax ethanol leaf extract modulates glucokinase and glucose-6–phosphatase activities in streptozotocin induced diabetic rats
《Journal of Coastal Life Medicine》2017年第4期162-166,共5页Osasenaga Macdonald Ighodaro Oluseyi Adeboye Akinloye Regina Ngozi Ugbaja Samuel Olatunbosun Omotainse 
Objective: To examine the effects of Sapium ellipticum (S. ellipticum) extract on hepatic activities of glucokinase and glucose-6-phosphatase in streptozotocin (STZ)-induced diabetic Wistar rats.Methods: STZ-induced d...
关键词：Sapium ellipticum GLUCOSE homeostasis Diabetes Glucokinse GLUCOSE-6-PHOSPHATASE 
Diagnosis of hepatic glycogenosis in poorly controlled type 1 diabetes mellitus被引量：1
《World Journal of Diabetes》2014年第6期882-888,共7页Stefania Giordano Antonio Martocchia Lavinia Toussan Manuela Stefanelli Francesca Pastore Antonio Devito Marcello G Risicato Luigi Ruco Paolo Falaschi 
Hepatic glycogenosis(HG) in type 1 diabetes is a underrecognized complication. Mauriac firstly described the syndrome characterized by hepatomegaly with altered liver enzymes, growth impairment, delay puberty and Cush...
关键词：Hepatic glycogenosis Type 1 diabetes mellitus HEPATOMEGALY GLYCOGEN Glucose transporters Insulin GLUCOKINASE Glycogen synthase GLUCOSE-6-PHOSPHATASE 
Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin被引量：36
《Acta Pharmacologica Sinica》2009年第2期202-208,共7页Shao-yu WU Guang-fa WANG Zhong-qiu LIU in-jun RAO Lin Lü Wei XU Shu-guang WU Jia-jie ZHANG 
Aim： Hepatic glycogen phosphorylase （GP） and glucose-6-phosphatase （G6Pase） play an important role in the control of blood glucose homeostasis and are proposed to be potential targets for anti-diabetic drugs. Gen...
关键词：type 2 diabetes GENIPOSIDE glycogen phosphorylase GLUCOSE-6-PHOSPHATASE hepatic glucose-regulating enzymes hypoglycemic agents 
Anti-diabetic property of ethanolic extract of Andrographis paniculata in streptozotocin-diabetic rats被引量：9
《Acta Pharmacologica Sinica》2000年第12期102-109,共8页Benny Kwong-Huat TAN 
AIM: To investigate the anti-diabetic effect of a crude ethanolic extract of Andrographis paniculata in normal and streptozotocin ( STZ )-induced diabetic rats. METHODS & RESULTS: Oral administration of the extract at...
关键词：ANDROGRAPHIS paniculata diabetes MELLITUS glucose tolerance test insulin leptin triglyc-erides cholesterol GLUCOSE-6-PHOSPHATASE GLYCOGEN 
HEXOKINASE, GLUCOSE-6-PHOSPHATASE DEHYDROGENASE AND ALEOSE REDUCTASE IN HUMAN FETAL LENSES
《眼科学报》1991年第1期31-33,共3页Winifred Mao 
The lens HK, G6PD, AR activity and its relationship with fetal age was determined.There is a positive correlation between the age of fetus and the activity(IU/mg pro.) of HK and G6PD(r=0.8069, 0.8204, P<0.01) and a ne...
关键词：HK AR GLUCOSE-6-PHOSPHATASE DEHYDROGENASE AND ALEOSE REDUCTASE IN HUMAN FETAL LENSES HEXOKINASE 
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