GENE-SILENCING

作品数：4被引量：5H指数：1
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Promoter Region Analysis of STAMP1/STEAP2 Gene-Silencing of STAMP1/STEAP2 Gene Triggers P53 Upregulation
《CellBio》2023年第1期1-9,共9页Ceren Gönen 
Prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer mortality in men in the Western World. In the initial stages, prostate cancer is dependent on androgens for growth which is ...
关键词：LNCAP STAMP1/STEAP2 P53 RT-PCR 
DNAzyme as a rising gene-silencing agent in theranostic settings
《Neural Regeneration Research》2022年第9期1989-1990,共2页Nan Zhang 
supported by a National Ataxia Foundation Young Investigator-SCA Award,No.93000(to NZ).
Decades of biochemical studies have advanced DNA beyond its primary role as genetic blueprint.DNAzymes are single-stranded enzymatic DNA molecules that do not exist in nature.They are ideal candidates for gene silenci...
关键词：compatibility auxiliary BATCH 
Recent advances of DNAzyme-based nanotherapeutic platform in cancer gene therapy
《Biophysics Reports》2020年第6期256-265,共10页Wendi Huo Xiaona Li Bei Wang Haoran Zhang Jinchao Zhang Xinjian Yang Yi Jin 
The work was supported by the National Natural Science Foundation of China(21603051);the Natural Science Foundation of Hebei Province(B2018201221,B2018201157);Hebei Youth top talent project,Key Projects of Education Department of Hebei Province(ZD2018036);Undergraduate Innovation and Entrepreneurship Training Program of Hebei University(2020351).
Deoxyribozyme(or denoted as DNAzyme),which is produced by in vitro screening technology,has gained extensive research interest in the field of biomedicine due to its high catalytic activity and structure identificatio...
关键词：DNAZYME Cancer therapy GENE-SILENCING NANOCARRIER 
Recent advances in DNAzyme-based gene silencing被引量：5
《Science China Chemistry》2017年第5期591-601,共11页Huanhuan Fan Xiaobing Zhang Yi Lu 
supported by the National Key Scientific Program of China(2011CB911000);the National Basic Research Program of China(2013CB932702);the National Natural Science Foundation of China(21325520,21327009,J1210040,21177036);the National Instrumentation Program(2011YQ030124);the Foundation for Innovative Research Groups of NSFC(21521063)
DNAzymes, generated through in vitro selection processes, are single-stranded DNA catalysts that can catalyze a wide variety of reactions, such as RNA or DNA cleavage and ligation or DNA phosphorylation. Based on spec...
关键词：DNAZYMES GENE-SILENCING delivery STABILITY COFACTORS 
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