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作品数:64被引量:257H指数:9
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相关领域:医药卫生生物学更多>>
相关作者:陈友国沈宗姬陈小平王钊廖鼐更多>>
相关机构:苏州大学第四军医大学东南大学上海大学更多>>
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相关基金:国家自然科学基金国家高技术研究发展计划北京市自然科学基金湖北省自然科学基金更多>>
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Surface-enhanced Raman scattering on nanomaterials for cancer and pathogens diagnosis
《Nano Research》2025年第2期650-674,共25页Jingjing Wu Baohong Zhang Lei Xu Yanyu Zhao Tao Chen Jie Lin Anran Li 
This work was supported by National Natural Science Foundation of China(Nos.62401053 and 12374390);the Fundamental Research Funds for the Central Universities,the member of Youth Innovation Promotion Association Foundation of CAS,China(No.2023310);the Key Scientific and Technological Special Project of Ningbo City(No.2023Z209).
Surface-enhanced Raman scattering(SERS)is a non-invasive spectroscopic technique that provides specific chemical fingerprint information for biomarkers in cancer and pathogen diagnosis.However,the SERS strategies are ...
关键词:surface-enhanced Raman scattering(SERS) SERS-active nanomaterials cancer and pathogen diagnosis artificial intelligence(Al)technology 
AP-1 and SP1 trans-activate the expression of hepatic CYP1A1 and CYP2A6 in the bioactivation of AFB1 in chicken
《Science China(Life Sciences)》2024年第7期1468-1478,共11页Jiang Deng Jia-Cheng Yang Yue Feng Ze-Jing Xu Kamil Kuča Meng Liu Lv-Hui Sun 
partly supported by the Chinese Natural Science Foundation Projects(31772636,32072775,32272915);the National Key Research and Development Program of China(2023YFD1301003);the Fundamental Research Funds for the Central Universities(2662023DKPY002);the Top-notch Young Talent Supporting Program to LHS,a gift from Beijing Deyuanshun Biotechnology Co.,Ltd。
Dietary exposure to aflatoxin B1(AFB1)is harmful to the health and performance of domestic animals.The hepatic cytochrome P450s(CYPs),CYP1A1 and CYP2A6,are the primary enzymes responsible for the bioactivation of AFB1...
关键词:aflatoxin B1 CYP1A1 CYP2A6 SP1 AP-1 transcriptional activation 
Metal coordination-driven assembly of stimulator of interferon genes-activating nanoparticles for tumor chemo-immunotherapy
《BMEMat(BioMedical Engineering Materials)》2024年第2期118-133,共16页Guiqiang Zhang Ning Wang Yuan Ma Shumei Zhai To Ngai Shilei Ni Xinyi Jiang Jianwei Jiao Jiwei Cui 
Shandong Traditional Chinese Medicine Technology Project,Grant/Award Number:Q-2023127;Innovation Project of Jinan Science and Technology Bureau,Grant/Award Number:2020GXRC022;Project for Scientific Research Innovation Team of Young Scholars in Colleges and Universities of Shandong Province,Grant/Award Numbers:2020KJC001,2022KJ196;National Natural Science Foundation of China,Grant/Award Number:22372091;Natural Science Foundation of Shandong Province,Grant/Award Number:ZR2023MB081。
Activating the stimulator of interferon genes(STING)signaling pathway is critical for enhancing antitumor immunity and remodeling the immunosuppressive tumor microenvironment(TME).Herein,we report the preparation of S...
关键词:amino acid metabolism immunotherapy NANOPARTICLES self-assembly STING 
MEMS-actuated terahertz metamaterials driven by phase-transition materials
《Frontiers of Optoelectronics》2024年第2期23-32,共10页Zhixiang Huang Weipeng Wu Eric Herrmann Ke Ma Zizwe A.Chase Thomas A.Searles M.Benjamin Jungfleisch Xi Wang 
supported by NSF through the University of Delaware Materials Research Science and Engineering Center DMR-2011824.
The non-ionizing and penetrative characteristics of terahertz(THz)radiation have recently led to its adoption across a variety of applications.To effectively utilize THz radiation,modulators with precise control are i...
关键词:METAMATERIALS MEMS THZ VO_(2) Phase-transition material 
Spatial dynamics of a reaction-diffusion SIS epidemic model with mass-action-type nonlinearity
《International Journal of Biomathematics》2024年第4期75-104,共30页Renhu Wang Xuezhong Wang 
supported by the NNSF of China(Grant No.12061032).
This work is devoted to investigate the global asymptotic stability of equilibriums for a reaction-diffusion susceptible-infected-susceptible(SIS)epidemic model with spatial heterogeneity and mass-action-type nonlinea...
关键词:DISCRETIZATION basic reproduction number Lyapunov functional global stability spatial heterogeneity 
Observer-based dynamic event-triggered control for distributed parameter systems over mobile sensor-plus-actuator networks
《Chinese Physics B》2024年第4期237-243,共7页穆文英 庄波 邱芳 
Project supported by the National Natural Science Foundation of China (Grant No.62073045)。
We develop a policy of observer-based dynamic event-triggered state feedback control for distributed parameter systems over a mobile sensor-plus-actuator network.It is assumed that the mobile sensing devices that prov...
关键词:distributed parameter systems event-triggered control mobile sensors mobile actuators 
Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis被引量:2
《World Journal of Pediatric Surgery》2023年第4期244-255,共12页Zhan Wang Gu Weizhong Juan Zhou Daxing Tang 
supported by the National Key R&D Program of China(2018YFC100272)。
Objective To explore the characteristics and mechanism of sirtuin 1(SIRT1)in lipopolysaccharide(LPS)-activated pyroptosis in the renal tissue of children with congenital hydronephrosis(CHn).Methods We detected the exp...
关键词:SIRT1 NLRP3 CONGENITAL 
Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma被引量:1
《Journal of Genetics and Genomics》2023年第6期422-433,共12页Bo Gong Yi Liang Qian Zhang Huan Li Jialing Xiao Liang Wang Han Chen Wenjie Yang Xiaoqing Wang Yi Wang Zongze He 
supported by the grants from Department of Science and Technology of Sichuan Province,China(No.23ZDYF2212);Medico-Engineering Cooperation Funds from the University of Electronic Science and Technology of China(No.ZYGX2021YGLH209);the Department of Science and Technology of Sichuan Province(Nos.2022NSFSC0760 and 2022JDTD0024);the Chengdu Science and Technology Bureau(2022-YF05-01625-SN)。
Gliomas are the most prevalent and aggressive malignancies of the nervous system.Previous bioinformatic studies have revealed the crucial role of the secretory pathway kinase FAM20C in the prediction of glioma invasio...
关键词:GLIOMA Alternativepolyadenylation sites FAM20C Trans-activefactors 
Valerian (Valeriana officinalis) extract inhibits TNF-α and iNOS gene expression in mouse LPS-activated microglial cells
《Traditional Medicine Research》2022年第5期65-70,共6页Hashem Marawne Reza Mohammadhassan Zahra Mohammadalipour Sedigheh Ahmadpour 
Background:Inflammation and damage to neurons and other cells in the nervous system can cause disorders of the central nervous system.Microglial cells are activated by pathogen infection and injury to release nitric o...
关键词:microglial cells nitric oxide Valeriana officinalis TNF-Α INOS 
Generation and Application of a Luciferase Reporter Virus Based on Yellow Fever Virus 17D被引量:1
《Virologica Sinica》2021年第6期1456-1464,共9页Dan Li Jing-Long Ye Zhong-Yu Liu 
This work is supported by the National Natural Science Foundation of China(81871632 and 32070183);the Natural Science Foundation of Guangdong Province(2020A1515010656);the Creative Research Group Foster Project of the Sun Yat-sen University;supported by the One-Hundred People Project of the Sun Yat-sen University。
Yellow fever virus(YFV) is a re-emerging virus that can cause life-threatening yellow fever disease in humans.Despite the availability of an effective vaccine,little is known about the replication mechanism of YFV,and...
关键词:Yellow fever virus(YFV) 17D Reporter virus Cis-acting RNA elements Anti-viral medicines 
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