supported by the National Key Research and Development Program of China(No.2022YFA1207500);the National Natural Science Foundation of China(No.82394445 to D.C.and L.T.;82250710174 and 82030067 to D.C.;82161160342 to D.C.and L.Q.);the Shenzhen Science and Technology Research Funding(No.JCYJ20220818101414032 to L.T.;JSGGKQTD20210831174330015 to D.C.).
The origin of bone marrow osteoblasts is not totally understood.Recent findings demonstrated that bone marrow osteoblasts could be derived from a subpopulation of hypertrophic Col2^(+)/Col10^(+)chondrocytes which migr...
Supported by Sailing Program of Naval Medical University,Program of Shanghai Hongkou District Health Commission,No.2202-27;Special Funds for Activating Scientific Research of Shanghai Fourth People’s Hospital,No.sykyqd05801.
BACKGROUND The hypoxic environment during bone healing is important in regulating the differentiation of periosteal stem cells(PSCs)into osteoblasts or chondrocytes;however,the underlying mechanisms remain unclear.AIM...