Niemann-Pick disease (NPD) refers to a group of patients who have varying degrees of lipid storage and foam cell infiltration in tissues, as well as overlapping clinical features, including hepatosplenomegaly, insuffi...
Supported by the Medical and Health Technology Plan of Zhejiang Province,No.2020KY1086 and No.2022ZH086。
BACKGROUND Primary liver cancer is one of the most common malignant tumours,while primary splenic lymphoma is a rare malignancy.Thus,cases of hepatocellular carcinoma(HCC)combined with splenic lymphoma are extremely r...
National Natural Science Foundation of China,Joint Fund Project(grant No.U20A600);National Key R&D Program of China(grant No.2020YFC2002702);National Key Technology Research and Development Program(grant No.2016YFC1302802);Beijing Municipal Science and Technology Project(grant No.Z181100001618013).
Background:Type 1 autoimmune pancreatitis(AIP)is the pancreatic manifestation of IgG4-related disease.However,this benign disease can result in the peripancreatic vascular involvement(PVI)on occasion,which increases t...
Introduction: Sickle cell disease is the most common hemoglobinopathy in the world. Sickle cells are quickly fixed and destroyed by the elements of the reticuloendothelial system mainly in the spleen. It leads to a pa...
The study was funded by private funds(Poverty Foundation,Basel,Switzerland).
Background:Severe hepatosplenic complications arise in patients with chronic Schistosoma mansoni infection after heavy exposure to disease agents in endemic areas.These complications are rarely reported and,hence,unde...
National Natural Science Foundation of China,No.81870444;Tianjin Natural Science Foundation,No.19JCQNJC10300;Spring Bud Plan of Tianjin First Central Hospital,No.TFCHCL201801.
BACKGROUND The most effective treatment for advanced cirrhosis and portal hypertension is liver transplantation(LT).However,splenomegaly and hypersplenism can persist even after LT in patients with massive splenomegal...
Background: Inhabitants from malaria endemic zones often present with enlarged spleen, mainly due to hyper reactive malarial splenomegaly (HMS), and it is seen more commonly associated with elevated l...
Objective To retrospectively analyzed the impact of splenomegaly on outcomes in patients with chronic myelomonocytic leukemia (CMML) receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT).Methods Cli...
supported (in whole or part) by HCA Healthcare and/or an HCA Healthcare affiliated entity
BACKGROUND Histiocytic sarcoma(HS)of the spleen is reported to be a rare and lethal disease.The clinicopathological features of splenic HS have not been well described.The objective of this paper is to describe the di...
Supported by the National Natural Science Foundation of China,No.81760514;Youth Science Fund of Jiangxi Provincial Science and Technology Department,No.20161BAB215252
BACKGROUND Hand-assisted laparoscopic splenectomy(HALS) can help overcome the drawbacks of laparoscopic splenectomy(LS) while maintaining its advantages.AIM To evaluate the efficacy and advantages of HALS for splenome...