This work was supported by grants from the Capital Health Research and Development of Special Program(No.2014-2-2013);the Beijing Excellent Talent Training Project Grant(No.201600026833ZK07);the National Science-Technology Support Plan(No.2014BAI04B02);the Project of Beijing Municipal Health Commission(No.PXM 2019_026283_000002).
Background:Mutations in the isocitrate dehydrogenase 1(IDH1)and IDH2 genes are important for both the integrated diagnosis and the prognosis of diffuse gliomas.The p.R132H mutation of IDH1 is the most frequently obser...
The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. However, the subsequent identification of oncogenes and tumor suppressor genes has displaced Wa...
Grade II oligodendrogliomas are rare and slow growing tumors, making long-term follow up difficult, but necessary for better understanding. In this retrospective study a review of all grade II oligodendrogliomas encou...
Transgenic tomato (Solanum lycopersicum) plants were generated expressing a fragment of the mitochon- drial NAD-dependent isocitrate dehydrogenase gene (SIIDH1) in the antisense orientation. The transgenic plants ...