ISOCITRATE

作品数:4被引量:6H指数:2
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相关领域:医药卫生更多>>
相关期刊:《Chinese Medical Journal》《世界最新医学信息文摘》《Molecular Plant》《Journal of Cancer Therapy》更多>>
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Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas被引量:4
《Chinese Medical Journal》2019年第24期2920-2926,共7页Lei-Ming Wang Zhuo Li Yue-Shan Piao Yan-Ning Cai Li-Yan Zhang Hai-Jing Ge Wei-Wei Xu De-Hong Lu 
This work was supported by grants from the Capital Health Research and Development of Special Program(No.2014-2-2013);the Beijing Excellent Talent Training Project Grant(No.201600026833ZK07);the National Science-Technology Support Plan(No.2014BAI04B02);the Project of Beijing Municipal Health Commission(No.PXM 2019_026283_000002).
Background:Mutations in the isocitrate dehydrogenase 1(IDH1)and IDH2 genes are important for both the integrated diagnosis and the prognosis of diffuse gliomas.The p.R132H mutation of IDH1 is the most frequently obser...
关键词:ISOCITRATE DEHYDROGENASE 1 ISOCITRATE DEHYDROGENASE 2 TELOMERASE reverse transcriptase GLIOMA OLIGODENDROGLIOMA 
Inborn and acquired metabolic defects in cancer
《世界最新医学信息文摘》2015年第5期6-,共1页Christian Frezza Patrick J Pollard Eyal Gottlieb 
The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. However, the subsequent identification of oncogenes and tumor suppressor genes has displaced Wa...
关键词:CANCER Metabolism Mutation SUCCINATE DEHYDROGENASE FUMARATE hydratase ISOCITRATE DEHYDROGENASE 
Lobar Distribution of Low Grade Oligodendroglioma: Distribution, Molecular Characteristics, and Survival Based upon Location
《Journal of Cancer Therapy》2014年第13期1249-1258,共10页Donald A. Ross Shao Tao Sakir Gultekin Amy M. Ross 
Grade II oligodendrogliomas are rare and slow growing tumors, making long-term follow up difficult, but necessary for better understanding. In this retrospective study a review of all grade II oligodendrogliomas encou...
关键词:Grade II OLIGODENDROGLIOMAS FRONTAL Lobe Superior FRONTAL Gyrus 1p19q ISOCITRATE Dehydrogenase 1 
Mild Reductions in Mitochondrial NAD- Dependent Isocitrate Dehydrogenase Activity Result in Altered Nitrate Assimilation and Piqmentation But Do Not Impact Growth被引量:2
《Molecular Plant》2010年第1期156-173,共18页Agata Sienkiewicz-Porzucek Ronan Sulpice Sonia Osorio Ina Krahnert Andrea Leisse Ewa Urbanczyk-Wochniak Michael Hodges Alisdair R. Fernie Adriano Nunes-Nesi 
Transgenic tomato (Solanum lycopersicum) plants were generated expressing a fragment of the mitochon- drial NAD-dependent isocitrate dehydrogenase gene (SIIDH1) in the antisense orientation. The transgenic plants ...
关键词:Carbon metabolism nitrogen metabolism PHOTORESPIRATION photosynthesis mitochondria tomato. 
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