CROSS-SPECIES

作品数：39被引量：24H指数：3
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相关领域：生物学更多>>
相关作者：宋小凯李祥瑞更多>>
相关机构：南京农业大学更多>>
相关期刊：《Journal of Integrative Agriculture》《Horticulture Research》《Current Zoology》《Synthetic and Systems Biotechnology》更多>>
相关基金：国家自然科学基金中国博士后科学基金江苏高校优势学科建设工程资助项目福建省自然科学基金更多>>
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Cross-species single-cell transcriptomics reveals neuronal similarities and heterogeneity in amniote pallium
《Zoological Research》2025年第1期193-208,共16页Fu-Bao-Qian Huang Kuo Liao Yu-Nong Sun Zi-Hao Li Yan-Ru Zhang Ping-Fang Liao Si-Yuan Jiang Zhi-Yong Zhu Duo-Yuan Chen Ying Lei Shi-Ping Liu You-Ning Lin Zhen-Kun Zhuang 
supported by the National Key Research and Development Program (2022YEF0203200);National Science and Technology Innovation 2030 Major Program (STI2030-2021ZD0200100);National Key Research and Development Program (2018YFA0801400,2021YFA0805100)。
The amniote pallium,a vital component of the forebrain,exhibits considerable evolutionary divergence across species and mediates diverse functions,including sensory processing,memory formation,and learning.However,the...
关键词：Amniote Pallium evolution Cross-species comparison Comparative transcriptomics Single-nucleus RNA sequencing 
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model被引量：1
《Cell Research》2024年第12期830-845,共16页Xiaodong Yang Guole Liu Guihai Feng Dechao Bu Pengfei Wang Jie Jiang Shubai Chen Qinmeng Yang Hefan Miao Yiyang Zhang Zhenpeng Man Zhongming Liang Zichen Wang Yaning Li Zheng Li Yana Liu Yao Tian Wenhao Liu Cong Li Ao Li Jingxi Dong Zhilong Hu Chen Fang Lina Cui Zixu Deng HaipingJiang Wentao Cui Jiahao Zhang Zhaohui Yang Handong Li Xingjian He Liqun Zhong Jiaheng Zhou Zijian Wang Qingging Long Ping Xu Hongmei Wang Zhen Meng Xuezhi Wang Yangang Wang Yong Wang Shihua Zhang Jingtao Guo Yi Zhao Yuanchun Zhou Fei Li Jing Liu Yiqiang Chen Ge Yang Xin Li Baoyang Hu Wei Li Fei Gao Leqian Yu Qi Gu Weiwei Zhai Zhengting Zou Jingqi Yu Wenhui Wu Xinxin Lin Yu Zou Yongshun Ren Fan Li Yixiao Zhao Yike Xin Longfei Han Shuyang Jiang Kai Ma Qicheng Chen Haoyuan Wang Huanhuan Wu Chaofan He Yilong Hu Shuyu Guo Yiyun Li Zaitian Wang Huimin He Shan Zong Jiajia Wang Yan Chen Chunyang Zhang Chengrui Wang Qingqing Long Ran Zhang Meng Xiao Yining Wang Xin Qin Jiaxin Qin Chenhao Li Zhufeng Xu Zeyuan Zhang Xiaoning Qi Wuliang Huang Yaoru Luo Qinxuan Luo Ziwen Liu Teng Wang Yiming Huang Shirui Li Kangning Dong Qunlun Shen 
This work was also supported by CAS Project for Young Scientists in Basic Research(YSBR-076 and YSBR-034);the National Natural Science Foundation of China(31971289,32341013,91954201,62202455,and 32341019);the Informatization Plan of Chinese Academy of Sciences(CAS-WX2021SF-0101).
Deciphering universal gene regulatory mechanisms in diverse organisms holds great potential for advancing our knowledge of fundamental life processes and facilitating clinical applications.However,the traditional rese...
关键词：KNOWLEDGE MECHANISMS FOUNDATION 
A cross-species foundation model for single cells
《Cell Research》2024年第12期818-819,共2页Korbinian Traeuble Matthias Heinig 
Foundation models in transcriptomics have gained attention due to their ability to generalize across tasks with limited labeled data. GeneCompass builds upon these models by incorporating prior biological knowledge an...
关键词：CROSS gained FOUNDATION 
Integrative cross-species transcriptome analysis reveals earlier occurrence of myelopoiesis in pre-circulation primates compared to mice
《Zoological Research》2024年第6期1276-1286,共11页Junjie Du Zongcheng Li Yandong Gong Yu Lan Bing Liu 
supported by the Beijing Natural Science Foundation(5222035);Beijing Nova Program(Z211100002121033,20230484407);National Key R&D Program of China(2021YFA0805703,2021YFA1100901,2022YFA1105700);National Natural Science Foundation of China(31930054,32100646,82370107,82270118);Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2017ZT07S347)。
Hematopoiesis originates in the yolk sac,which forms prior to the establishment of blood circulation and exhibits distinct developmental processes between primates and mice.Despite increasing appreciation of yolk sac ...
关键词：Yolk sac HEMATOPOIESIS Macrophage Integrative analysis Single-cell RNA sequencing 
PCMD:A multilevel comparison database of intraand cross-species metabolic profiling in 530 plant species
《Plant Communications》2024年第10期33-44,共12页Yue Hu Yao Ruan Xin-Le Zhao Feng Jiang Dongxu Liu Qiang Zhu Qing-Ye Zhang Qing-Yong Yang 
supported by the National Natural Science Foundation of China(32322061 and 32070559);the Fundamental Research Funds for the Central University HZAU(2662022XXYJ007 and 2662023XX PY001);the China Postdoctoral Science Foundation(2024M751038)。
Comparative metabolomics plays a crucial role in investigating gene function,exploring metabolite evolution,and accelerating crop genetic improvement.However,a systematic platform for intra-and crossspecies comparison...
关键词：comparative metabolomics plant database multilevel comparison metabolite characteristics 
Learning Sequential and Structural Dependencies Between Nucleotides for RNA N6-Methyladenosine Site Identification
《IEEE/CAA Journal of Automatica Sinica》2024年第10期2123-2134,共12页Guodong Li Bowei Zhao Xiaorui Su Dongxu Li Yue Yang Zhi Zeng Lun Hu 
supported in part by the National Natural Science Foundation of China(62373348);the Natural Science Foundation of Xinjiang Uygur Autonomous Region(2021D01D05);the Tianshan Talent Training Program(2023TSYCLJ0021);the Pioneer Hundred Talents Program of Chinese Academy of Sciences.
N6-methyladenosine(m6A)is an important RNA methylation modification involved in regulating diverse biological processes across multiple species.Hence,the identification of m6A modification sites provides valuable insi...
关键词：Cross-domain reconstruction cross-species prediction N6-methyladenosine(m6A)modification site RNA sequence sequential and structural dependencies 
Suppression of host plant defense by bacterial small RNAs packaged in outer membrane vesicles
《Plant Communications》2024年第4期239-250,共12页Yan Wu Sai Wang Peihong Wang Wenhan Nie Iftikhar Ahmad Panagiotis F.Sarris Gongyou Chen Bo Zhu 
supported by the National Natural Science Foundation of China (32272479,32200142);Open Project Program of State Key Laboratory of Rice Biology (20190109);Open Project Program of State Key Laboratory for Biology of Plant Diseases and Insect Pests (SKLOF202201);Zhejiang Province Ecological Environment Research and Promotion Project (2020HT0009);Shanghai Committee of Science and Technology (19390743300 and 21ZR1435500);Chongqing Natural Science Foundation (CSTB2022NSCQ-MSX0524).
Noncoding small RNAs(sRNAs)packaged in bacterial outer membrane vesicles(OMVs)function as novel mediators of interspecies communication.While the role of bacterial sRNAs in enhancing virulence is well established,the ...
关键词：small RNAs outer membrane vesicles Xanthomonas oryzae stomatal immunity cross-species communication 
SARS-CoV-2 infection in animals: Patterns, transmission routes, and drivers
《Eco-Environment & Health》2024年第1期45-54,共10页Ruying Fang Xin Yang Yiyang Guo Bingjie Peng Ruixuan Dong Sen Li Shunqing Xu 
supported by the National Natural Science Foundation of China(42107458).
The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is more widespread in animals than previously thought,and it may be able to infect a wider range of domestic and wild species.To effectively control the s...
关键词：SARS-CoV-2 Biophysical factors Anthropogenic factors Transmission CROSS-SPECIES 
Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus
《Zoological Research》2023年第6期1015-1025,共11页Runchu Zhao Sheng Niu Pu Han Yue Gao Dezhi Liu Chunliang Luo Honghui Liu Bo Liu Yanli Xu Jianxun Qi Zhihai Chen Weifeng Shi Lili Wu George F.Gao Qihui Wang 
supported by the National Key R&D Program of China (2022YFC2303403);National Natural Science Foundation of China (82225021);supported by the Chinese Academy of Sciences (YSBR-010 and Y2022037)。
Following the outbreak of coronavirus disease 2019(COVID-19),several severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-related coronaviruses have been discovered.Previous research has identified a novel line...
关键词：SARS-CoV-2-related coronavirus RsYN04 ACE2 Antibody Structure 
Cross-species single-cell transcriptomic analysis of animal gastric antrum reveals intense porcine mucosal immunity
《Cell Regeneration》2023年第1期133-146,共14页Xiaodan Wang Fan Hong Haonan Li Yalong Wang Mengxian Zhang Shibo Lin Hui Liang Hongwen Zhou Yuan Liu Ye‑Guang Chen 
supported by grants from the National Key Research and Development Program of China(2017YFA0103601);the National Natural Science Foundation of China(31988101 and 31730056 to YGC).
As an important part of the stomach,gastric antrum secretes gastrin which can regulate acid secretion and gastric emptying.Although most cell types in the gastric antrum are identified,the comparison of cell compositi...
关键词：Single cell RNA-seq Gastric antrum CROSS-SPECIES Porcine immunity 
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