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Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?: 《Neural Regeneration Research》2025年第9期2596-2597,共2页Christopher J.O’Connell Matthew J.Robson; Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic...; 关键词：SUSTAINED ORANGE dynamic

Artificial intelligence-enabled microfluidic cytometer using gravity-driven slug flow for rapid CD4^(+)T cell quantification in whole blood: 《Microsystems & Nanoengineering》2025年第1期441-452,共12页Desh Deepak Dixit Tyler P.Graf Kevin J.McHugh Peter B.Lillehoj; supported in part by the National Institutes of Health(R21CA283852);a Rice University COVID-19 Research Award(U50807).; The quantification of immune cell subpopulations in blood is important for the diagnosis,prognosis and management of various diseases and medical conditions.Flow cytometry is currently the gold standard technique for ...; 关键词：microfluidic cytometer gravity driven slug flow cell quantificationhoweverit flow cytometry portable instrumentation whole blood artificial intelligence quantification immune cell subpopulations

Uncovering immune cell heterogeneity in hepatocellular carcinoma by combining single-cell RNA sequencing with T-cell receptor sequencing: 《World Journal of Hepatology》2025年第2期140-158,共19页Xin-Yu Gu Shuang-Lin Gu Zi-Yi Chen Jin-Long Tong Xiao-Yue Li Hui Dong Cai-Yun Zhang Wen-Xian Qian Xiu-Chang Ma Chang-Hua Yi Yong-Xiang Yi; Supported by the Scientific Research Topic of Jiangsu Provincial Health Care Commission,No.M2021017;the High-level Talent Research Project of the Second Hospital of Nanjing,No.0313504;the Nanjing Second Hospital Academic Leader Program,No.0313506.; BACKGROUND Understanding the status and function of tumor-infiltrating immune cells is essential for improving immunotherapeutic effects and predicting the clinical response in human patients with carcinoma.However,li...; 关键词：Single-cell RNA sequencing Paired T-cell receptor sequencing Hepatocellular carcinoma Immune cell subpopulations Tumor-infiltrating immune cells

Revolutionizing stem cell research:unbiased insights through single-cell sequencing: 《BIOCELL》2024年第11期1531-1542,共12页HAO WU NA HUO SITUO WANG ZIWEI LIU YI JIANG QUAN SHI; Stem cells have shown great application potential in wound repair,tissue regeneration,and disease treatment.Therefore,a full understanding of stem cells and their related regulatory mechanisms in disease treatment is ...; 关键词：Stem cell Single-cell sequencing Cellular heterogeneity SUBPOPULATIONS Functional analysis Lineage-tracing

Differences of gene expression profiles of different subpopulations of exhausted T cells in patients with active pulmonary tuberculosis: 《China Medical Abstracts(Internal Medicine)》2024年第3期168-168,共1页LIN Weifang; Objective To explore the differences of gene expression profiles of precursors of exhausted T cells(Tpex) and terminal exhausted T cells (Tex) in the peripheral blood of patients with active pulmonary tuberculosis (ATB).; 关键词：TUBERCULOSIS PULMONARY cells

Single-cell transcriptomics reveals neural stem cell trans-differentiation and cell subpopulations in whole heart decellularized extracellular matrix: 《Biophysics Reports》2024年第4期241-253,共13页Xiaoning Yang Yuwei Zhao Wei Liu Zhongbao Gao Chunlan Wang Changyong Wang Siwei Li Xiao Zhang; supported by Youth Talent Fund Project of Military Medical Research Institute(AMMS-QNPY-2021-005);the Joint Fund Project of the National Natural Science Foundation of China(U21A20394);National Natural Science Foundation of China Youth Fund(32201116).; The whole heart decellularized extracellular matrix(ECM)has become a promising scaffold material for cardiac tissue engineering.Our previous research has shown that the whole heart acellular matrix possesses the memor...; 关键词：Single-cell transcriptomics Neural stem cell TRANS-DIFFERENTIATION Decellularized extracellular matrix Cardiac lineage cells

An Integrated External Archive Local Disturbance Mechanism for Multi-Objective Snake Optimizer: 《Chinese Journal of Electronics》2024年第4期989-996,共8页Leifu GAO Zheng LIU; National Natural Science Foundation of China (Grant No. 12201275);Planning Fund of the Ministry of Education, Humanities and Social Sciences (Grant No. 21YJCZH204)。; It is an interesting research direction to develop new multi-objective optimization algorithms based on meta-heuristics. Both the convergence accuracy and population diversity of existing methods are not satisfactory....; 关键词：Multi-objective optimization Snake optimizer Adaptive mating between subpopulations strategy External archive local disturbance mechanism

Correction: Defining two subpopulations of marginal zone B cells: 《Cellular & Molecular Immunology》2024年第7期800-800,共1页

Subpopulations of regulatory T cells are associated with subclinical atherosclerotic plaques,levels of LDL,and cardiorespiratory fitness in the elderly被引量：2: 《Journal of Sport and Health Science》2024年第3期288-296,I0002,共10页Tim Böttrich Pascal Bauer Vincent Gröβer Magdalena Huber Hartmann Raifer Torsten Frech Svenja Nolte Theresa Dombrowski Franz Cemic Natascha Sommer Robert Ringseis Klaus Eder Karsten Krüger Christopher Weyh; funded by the Central Hessen Research Campus,Flexi Fund,Project No.20121_1_1.; Background:Atherosclerosis forms the pathological basis for the development of cardiovascular disease.Since pathological processes initially develop without clinically relevant symptoms,the identification of early mar...; 关键词：Cardiorespiratory fitness ELDERLY Regulatory T cells Subclinical atherosclerosis

Single-cell sequencing technology in diabetic wound healing:New insights into the progenitors-based repair strategies: 《World Journal of Stem Cells》2024年第5期462-466,共5页Zhen Xiang Rui-Peng Cai Yang Xiao Yong-Can Huang; Supported by Shenzhen Science and Technology Program,No.GJHZ20210705142543019;Guangdong Basic and Applied Basic Research Foundation,No.2023A1515220074.; Diabetes mellitus(DM),an increasingly prevalent chronic metabolic disease,is characterised by prolonged hyperglycaemia,which leads to long-term health consequences.Although much effort has been put into understanding ...; 关键词：Single-cell sequencing Diabetic wound healing Cell subpopulations Heterogeneity PATHOGENESIS Progenitor cells

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