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作品数:83被引量:125H指数:6
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Immunotherapy in gastric cancer with liver metastasis:Challenges and opportunities
《World Journal of Gastrointestinal Surgery》2024年第6期1513-1516,共4页Murat Bardakçi Yakup Ergun 
In this editorial,we review the article by Liu et al published in the World Journal of Gastrointestinal Surgery investigating the efficacy and safety of immunotherapy in patients with gastric cancer(GC)and liver metas...
关键词:Gastric cancer Liver metastasis IMMUNOTHERAPY Immune checkpoint in-hibitors Transarterial chemoembolization Tumor microenvironment 
Tumor microenvironment of cancer stem cells:Perspectives on cancer stem cell targeting被引量:2
《Genes & Diseases》2024年第3期275-302,共28页Qianqian Guo Yi Zhou Tianyuan Xie Yin Yuan Huilong Li Wanjin Shi Lufeng Zheng Xiaoman Li Wenzhou Zhang 
supported by the National Natural Science Foundation of China(No.82173842,82204432);the Medical Science and Technology Research Project of Henan Province,China(No.SBGJ202003010);the Henan Province Science and Technology Research Project(No.222102310414);the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions(China).
There are few tumor cell subpopulations with stem cell characteristics in tumor tis-sue,defined as cancer stem cells(CSCs)or cancer stem-like cells(CSLCs),which can recon-struct neoplasms with malignant biological beh...
关键词:Cancer stem cells Cancerstem-like cells Cellular factors Non-cellularfactors Tumor microenvironment 
Electric-Induced Cycloelimination for Simulating Structural Plasticity in Organic Nociceptors
《CCS Chemistry》2024年第6期1466-1476,共11页Zhiheng Zhu Kai Liu Haojie Huang Yangshuang Bian Mingcong Qin Chengyu Wang Wei Wen Mingliang Zhu Wenkang Shi Yanwei Liu Zhiyuan Zhao Huijuan Yan Hanlin Wang Yunqi Liu Yunlong Guo 
the National Key R&D Program(grant no.2018YFA0703200);the National Natural Science Foundation of China(grant nos.61890940 and 52003274);the Chinese Academy of Sciences(CAS)Project for Young Scientists in Basic Research(grant no.YSBR-053);the Strategic Priority Research Program of the CAS(grant no.XDB30000000);the CAS-Croucher Funding Scheme for Joint Laboratories,the CAS Cooperation Projects(grant no.121111KYSB20200036);Lu Jiaxi international team(grant no.GJTD-2020-02).
Continuous lifelong acquisition,updating,and finetuning of knowledge and skills is of crucial significance for the survival of humans.However,current neuromorphic devices exhibit obvious catastrophic forgetting when r...
关键词:electric-induced cycloelimination structural plasticity organic nociceptors organic transistors METAPLASTICITY 
Scarcity and Mental Health—Multiple Mediators of Sleep Quality and Life Satisfaction
《International Journal of Mental Health Promotion》2024年第6期449-462,共14页Na Liu Yan Zhang Junxiu Wang 
the Key Projects of Philosophy and Social Sciences Research,Ministry of Education(Grant Number 21JZD038).
Background:In the current social environment,scarcity,as a universally present objective state,profoundly impacts individuals’decision-making and health through the subjective feeling it induces,known as a“scarcity ...
关键词:SCARCITY sleep quality life satisfaction mental health multiple mediators 
Emerging materials and transistors for integrated circuits
《National Science Review》2024年第3期1-2,共2页Ming Liu Lian-Mao Peng 
The device technology for integrated circuits(ICs)has received a great deal of attention in the past decade since the mainstream silicon-based complementary metal-oxide-semiconductor(CMOS)field-effect transistor(FET)f...
关键词:TRANSISTOR COMPLEMENTARY constraints 
Electric-double-layer-gated 2D transistors for bioinspired sensors and neuromorphic devices被引量:2
《International Journal of Smart and Nano Materials》2024年第1期238-259,共22页Xiangde Lin Yonghai Li Yanqiang Lei Qijun Sun 
supported by the National Key Research and Development Program of China(2021YFB3200304);the National Natural Science Foundation of China(52073031),Beijing Nova Program(Z211100002121148);Fundamental Research Funds for the Central Universities(EOEG6801X2);the"Hundred Talents Program"of the Chinese Academy of Sciences.
Electric double layer(EDL)gating is a technique in which ions in an electrolyte modulate the charge transport in an electronic material through electrical field effects.A sub-nanogap capacitor is induced at the interf...
关键词:Electrical double layer transistors 2D materials SENSORS applications 
Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk被引量:2
《Genes & Diseases》2024年第1期103-134,共32页Kevin Qin Michael Yu Jiaming Fan Hongwei Wang Piao Zhao Guozhi Zhaoo Wei Zeng Connie Chen Yonghui Wang Annie Wang Zander Schwartz Jeffrey Hong Lily Song William Wagstaff Rex C.Haydon Hue H.Luu Sherwin H.Ho Jason Strelzow Russell R.Reid Tong-Chuan He Lewis L.Shi 
supported in part by research grants from the National Institutes of Health(No.CA226303 to TCH and No.DE030480 to RRR);the American Shoulder and Elbow Surgeons PJI Research Grant(LLS).JF was supported in part by research grants from the Natural Science Foundation of China(No.82102696);the 2019 Science and Technology Research Plan Project of Chongqing Education Commission(China)(No.KJQN201900410);the 2019 Funding for Postdoctoral Research(Chongqing Human Resources and Social Security Bureau No.298);WW was supported by the Medical Scientist Training Program of the National Institutes of Health(No.T32 GM007281);This project was also supported in partby The University of Chicago Cancer Center Support Grant(No.P30CA014599);the National Center for Advancing Translational Sciences(NCATS)of the National Institutes of Health through Grant Number 5UL1TR002389.
Wnt signaling plays a major role in regulating cell proliferation and differentiation.The Wnt ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via binding to Frizzled receptors an...
关键词:β-catenin Canonical Wnt Noncanonical Wnt Signal transduction Signaling crosstalk 
Plant Promoters and Terminators for High-Precision Bioengineering被引量:1
《BioDesign Research》2023年第1期86-105,共20页Emily G.Brooks Estefania Elorriaga Yang Liu James R.Duduit Guoliang Yuan Chung-Jui Tsai Gerald A.Tuskan Thomas G.Ranney Xiaohan Yang Wusheng Liu 
the USDA Floriculture and Nursery Research Initiative(FNRI)grant 8020-21000-071-23S;the USDA National Institute of Food and Agriculture(NIFA)Hatch project 02913;the Center for Bioenergy Innovation(CBI),which is a U.S.Department of Energy Bioenergy Research Center supported by the Office of Biological and Environmental Research in the DOE Office of Science.Oak Ridge National Laboratory is managed by UT-Battelle,LLC for the U.S.DOE under contract number DE-AC05-00OR22725。
High-precision bioengineering and synthetic biology require fine-tuning gene expression at both transcriptional and posttranscriptional levels.Gene transcription is tightly regulated by promoters and terminators.Promo...
关键词:expression PROMOTER PROXIMAL 
Fin field-effect transistors based on 2D Bi_(2)O_(2)Se——a huge innovation of 2D transistors device structure
《Science China Chemistry》2023年第9期2439-2440,共2页Qundong Fu Beng Kang Tay Zheng Liu 
The continuous downscaling(sub 5-nm nodes) of the processing technology is severely hampered by the shortchannel effects of the silicon(Si) material, which degrade the transistor's performance and raise the demand in ...
关键词:TRANSISTORS transistor OVERCOME 
Rational design of semiconductor metal oxide nanomaterials for gas sensing by template-assisted synthesis:a survey
《Frontiers of Information Technology & Electronic Engineering》2023年第7期945-963,共19页Yuanyang XUN Siqi LI Feiyu ZHANG Yan HONG Ke XU Ligang CHEN Song LIU Bin LI 
Project supported by the National Natural Science Foundation of China(No.62001097);the Natural Science Foundation of Heilongjiang Province(No.LH2020F001);the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(CAST)(No.YESS20210262);the China Postdoctoral Science FoundationFunded Project(No.2021M690571);the Heilongjiang Postdoctoral Fund,China(No.LBH-Z21096);the Fundamental Research Funds for the Central Universities,China(No.2572020BU04)。
Gas sensors have received extensive attention because of the gas pollution caused by rapid construction of urbanization and industrialization.Gas sensors based on semiconductor metal oxide(SMO)have the advantages of h...
关键词:Gas sensors Chemi-resistors Template-assisted methods NANOSTRUCTURE DIMENSION 
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