PROPAFENONE

作品数:16被引量:10H指数:2
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相关领域:医药卫生更多>>
相关作者:刘俊亭王妍高利娜蔡卫民徐军更多>>
相关机构:南京金陵医院南京医科大学中国医科大学江苏省人民医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《中国科技期刊数据库 医药》《World Journal of Gastroenterology》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金更多>>
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研究三磷酸腺苷(ATP)与普罗帕酮(propafenone)急诊转律阵发性室上性心动过速(PSVT)的效果
《中国科技期刊数据库 医药》2022年第11期41-44,共4页汤涛 
研究PSVT(阵发性室上性心动过速)急诊转律中普罗帕酮(propafenone)与三磷酸腺苷(ATP)的应用效果。方法 基于实验对照形式下纳入60例PSVT-阵发性室上性心动过速患者(收治时间,2019年10月至2021年10月)为观察对象,按照入院时间单双号法均...
关键词:PSVT(阵发性室上性心动过速) 急诊转律 普罗帕酮 三磷酸腺苷 
Development of Methodology for the Isolation and Determination of Propafenone in Blood Samples via HPLC
《Journal of US-China Medical Science》2015年第4期163-171,共9页Madina Alikhodjaeva Alisher Atahanov Mirzabotir Xamdamov 
In clinical practice, side effects of anti-arrhythmic medicines such as propafenone are commonly registered. Therapeutic drug monitoring is a solution to the problem regarding to side effects of drugs and aiming to co...
关键词:PROPAFENONE extraction TLC HPLC UV spectroscopy blood. 
Selective killing effect of oxytetracycline,propafenone and metamizole on A549 or Hela cells
《Chinese Journal of Cancer Research》2013年第6期662-670,共9页Jinhui Shao Guihua Feng 
the technical platform in Shandong University and Doctor research fund of Hubei University of Art and Science(2013B009)
Objective: To determine the selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Methods: Proliferation assay, lactate dehydrogenase (LDH) assay, apoptosis detecting, flow...
关键词:CANCER DRUG OXYTETRACYCLINE PROPAFENONE metamizol 
Effects of diltiazem and propafenone on the inactivation and recovery kinetics of fKv1.4 channel currents expressed in Xenopus oocytes被引量:1
《Acta Pharmacologica Sinica》2011年第4期465-477,共13页Dong ZHANG Shi-min WANG Hui CHEN Xue-jun JIANG Sheng-ping CHAO 
Aim: To investigate the effects of diltiazem, an L-type calcium channel blocker, and propafenone, a sodium channel blocker, on the inactivation and recovery kinetics of fKvl.4, a potassium channel that generates the ...
关键词:INACTIVATION RECOVERY Kv1.4 potassium channel DILTIAZEM PROPAFENONE two electrode voltage clamp technique 
propafenone HCL
《中国处方药》2009年第3期18-18,共1页
Watson制药公司是一家权威的专业制药公司。该公司近日宣布,作为一项预防措施,需要收回已向消费者售出的约100瓶225mg规格的propafenone HCL(盐酸普罗帕酮)片。
关键词:盐酸普罗帕酮片 药物 治疗方法 医疗卫生行业 发展现状 
体内普罗帕酮及其代谢物的GC-MS检验被引量:2
《分析测试学报》2007年第z1期44-46,共3页刘俊亭 高利娜 王妍 
In this paper,propafenone in judicial anatomy was quantitated and found to be 11.6 μg/mL in blood,17.8 μg/mL in urine,292 μg/g in gastric content and 196 μg/g in liver with GC-MS. Two metabolites from propafenone ...
关键词:PROPAFENONE METABOLITE GC-MS 
Electrophysiologic Effects of Propafenone on Ischemic Ventricular Tachyarrhythmias
《South China Journal of Cardiology》2006年第2期93-96,共4页Liu Musheng Ma Yanfeng Guo Zhibin 
Objectives To observe the electrophysiologic effects of propafenone (Prop) on ischemic ventricular tachyarrhythmias. Methods A canine ischemic ventricular tachyarrhythmia model was established in open-chest dogs sub...
关键词:Arrhythmia Ischemic Propafenone Electrophysiology 
Effect of CYP2D6~*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia被引量:1
《Acta Pharmacologica Sinica》2002年第11期1040-1044,共5页蔡卫民 徐军 陈冰 张馥敏 黄元铸 张银娣 
RAIM: To determine the effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia. METHODS: Seventeen Chinese patients with ventricular premature contractions (VPC≥10...
关键词:PROPAFENONE PHARMACODYNAMICS cytochrome P-450 CYP2D6 ventricular dysfunction GENOTYPE 
Stereoselective metabolism of propafenone by human liver CYP3A4 expressed in transgenic Chinese hamster CHL cells lines
《Acta Pharmacologica Sinica》2001年第10期944-948,共5页周权 姚彤炜 余应年 曾苏 
Project supported by the National Natural Science Foundation of China(No 39770868 and No 39670801);Zhejiang Natural Science Foundation (No RC97016)
AIM: To investigate the stereoselective metabolism of propafenone ( PPF ) by human liver CYP3A4. METHODS: A chiral and an achiral HPLC were combined to determine the enantiomer of PPF in S9 incubates prepared from tra...
关键词:PROPAFENONE STEREOISOMERS METABOLISM cytochrome P-450 CYP3A4 
Simultaneous modeling of pharmacokinetics and pharmacodynamics of propafenone in healthy subjects被引量:1
《Acta Pharmacologica Sinica》2001年第10期956-960,共5页蔡卫民 张银娣 陈冰 蔡明虹 罗建平 凌树森 
AIM: To study the simultaneous modeling of pharmacokinetics and pharmacodynamics (PK-PD) of propafenone (Pro) in healthy subjects. METHODS: Ten healthy Chinese volunteers, 5 extensive metabolizers (EM) and 5 intermedi...
关键词:PROPAFENONE PHARMACOKINETICS MODELS cytochrome P-450 CYP2D6 
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