NANOSCOPY

作品数：33被引量：78H指数：5
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Visualization of cristae and mtDNA interactions via STED nanoscopy using a low saturation power probe被引量：2
《Light(Science & Applications)》2024年第9期1741-1756,共16页Wei Ren Xichuan Ge Meiqi Li Jing Sun Shiyi Li Shu Gao Chunyan Shan Baoxiang Gao Peng Xi 
supported by the National Key R&D Program of China(2022YFC3401100);National Natural Science Foundation of China(22177024,62025501,31971376,92150301).
Mitochondria are crucial organelles closely associated with cellular metabolism and function.Mitochondrial DNA(mtDNA)encodes a variety of transcripts and proteins essential for cellular function.However,the interactio...
关键词：METABOLISM SATURATION utilizing 
Multiplexed stimulated emission depletion nanoscopy(mSTED)for 5-color live-cell long-term imaging of organelle interactome被引量：1
《Opto-Electronic Advances》2024年第7期17-26,共10页Yuran Huang Zhimin Zhang Wenli Tao Yunfei Wei Liang Xu Wenwen Gong Jiaqiang Zhou Liangcai Cao Yong Liu Yubing Han Cuifang Kuang Xu Liu 
supported by the following grants:National Natural Science Foundation of China(62125504,62361166631);STI 2030-Major Projects(2021ZD0200401);the Fundamental Research Funds for the Central Universities(226-2022-00201);the Open Project Program of Wuhan National Laboratory for Optoelectronics(2021WNLOKF007).
Stimulated emission depletion microscopy(STED)holds great potential in biological science applications,especially in studying nanoscale subcellular structures.However,multi-color STED imaging in live-cell remains chal...
关键词：optical nanoscopy phasor analysis multicolor live cell imaging 
Acoustofluidic scanning fluorescence nanoscopy with a large field of view
《Microsystems & Nanoengineering》2024年第3期159-167,共9页Geonsoo Jin Neil Upreti Joseph Rich Jianping Xia Chenglong Zhao Tony Jun Huang 
support from the National Institutes of Health(R01GM143439,R01HD103727,UH3TR002978,and U18TR003778);the National Science Foundation(CMMI-2104295);a National Science Foundation Graduate Research Fellowship under Grant no.2139754.
Large-field nanoscale fluorescence imaging is invaluable for many applications,such as imaging subcellular structures,visualizing protein interactions,and high-resolution tissue imaging.Unfortunately,conventional fluo...
关键词：FIELD RESOLUTION utilize 
Photoswitchable vibrational nanoscopy with sub-100-nm optical resolution被引量：1
《Advanced Photonics》2023年第6期29-36,共8页Jianpeng Ao Xiaofeng Fang Liyang Ma Zhijie Liu Simin Wu Changfeng Wu Minbiao Ji 
the financial support from the National Key Research and Development Program of China(Grant No.2021YFF0502900);the National Natural Science Foundation of China(Grant Nos.61975033 and 81771930);the Shanghai Municipal Science and Technology Major Project(Grant Nos.2017SHZDZX01 and 2018SHZDZX01);the financial support from the Shenzhen Science and Technology Innovation Commission(Grant No.KQTD20170810111314625);the National Key Research and Development Program of China(Grant No.2018YFB0407200).
Stimulated Raman scattering(SRS)microscopy has shown superior chemical resolution due to the much narrower vibrational spectral bandwidth than its fluorescence counterpart.However,breaking the diffraction-limited spat...
关键词：stimulated Raman scattering superresolution microscopy vibrational imaging PHOTOSWITCHING 
Characterizing and controlling infrared phonon anomaly of bilayer graphene in optical-electrical force nanoscopy
《Light(Science & Applications)》2023年第12期2700-2710,共11页Junghoon Jahng Sunho Lee Seong-Gu Hong Chang Jun Lee Sergey G.Menabde Min Seok Jang Dong-Hyun Kim Jangyup Son Eun Seong Lee 
support of the KPFM calibration.J.J.,S.L.and E.S.L.acknowledge the supports from the National Research Foundation of Korea(NRF)grant(MSIT;Grant No.2022R1C1C1008766);the Nano Material Technology Development Program(Grant No.2016M3A7B6908929)funded by the Korea government.S.G.M.;M.S.J.acknowledge the Basic Science Research Program through the NRF funded by the Ministry of Education(Grant No.2021R1I1A1A01057510);the support of the NRF grant funded by MSIT(2022R1A2C2092095).D.K.;J.S.acknowledged to the National Research Council of Science&Technology(NST)grant by the Korea government(MSIT)(No.CRC-20-01-NFRI)and the KIST Institutional program(2E32634).
We,for the first time,report the nanoscopic imaging study of anomalous infrared(IR)phonon enhancement of bilayer graphene,originated from the charge imbalance between the top and bottom layers,resulting in the enhance...
关键词：ELECTRICAL FORCE OPTICAL 
Toward augmenting tip-enhanced nanoscopy with optically resolved scanning probe tips被引量：1
《Advanced Photonics Nexus》2023年第2期48-64,共17页Jeremy Belhassen Simcha Glass Eti Teblum George A.Stanciu Denis E.Tranca Zeev Zalevsky Stefan G.Stanciu Avi Karsenty 
support of the Romanian Executive Agency for Higher Education,Research,Development and Innovation Funding(Grant Nos.RO-NO-2019-0601 MEDYCONAI and PN-III-P1-1.1-TE-2019-1339 OPTIGAN);the support of Horizon 2020 Attract(Phase 1)via the TEFPLASNOM project.
A thorough understanding of biological species and emerging nanomaterials requires,among other efforts,their in-depth characterization through optical techniques capable of nanoresolution.Nanoscopy techniques based on...
关键词：tip-enhanced nanoscopy scanning probes COMSOL simulations nano-objects optical modeling 
Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
《Light(Science & Applications)》2023年第4期502-504,共3页Rui Pu Qiuqiang Zhan 
supported by the National Natural Science Foundation of China(62122028,11974123);Guangdong Basic and Applied Basic Research Foundation(2023B1515040018,2018B030306015,2019A050510037).
Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles,i.e.,exosome.The number of surface antigens o...
关键词：surface RESOLUTION REVEALING 
Application and development of fluorescence probes in MINFLUX nanoscopy(invited paper)被引量：1
《Journal of Innovative Optical Health Sciences》2023年第1期67-78,共12页Jing Wang Zhen Zhang Hongyu Shen Qi Wu Min Gu 
supported by the Science and Technology Commission of Shanghai Municipality (21DZ1100500);the Shanghai Municipal Science and Technology Major Project;the Shanghai Frontiers Science Center Program (2021-2025 No.20);Shanghai Hong Kong,Macao,and Taiwan Cooperation Project (No.19490760900).
The MINimal emission FLUXes(MINFLUX)technique in optical microscopy,widely recognized as the next innovative fluorescence microscopy method,claims a spatial resolution of 1-3 nm in both dead and living cells.To make u...
关键词：Fluorescence probes MINFLUX nanoscopy photoblinking super-resolution imaging labeling strategy 
Fluorescence Nanoscopy in Neuroscience被引量：1
《Engineering》2022年第9期29-38,共10页Yangyundou Wang Jian Lin Qiming Zhang Xi Chen Haitao Luan Min Gu 
the Zhangjiang National Innovation Demonstration Zone(ZJ2019-ZD-005);the National Natural Science Foundation of China(11874267);supported by a fellowship of the China Postdoctoral Science Foundation(2020M671169)。
Fluorescence nanoscopy provides imaging techniques that overcome the diffraction-limited resolution barrier in light microscopy,thereby opening up a new area of research in biomedical imaging in fields such as neurosc...
关键词：Fluorescence imaging Diffraction limit Nanoscale resolution NEUROSCIENCE 
Versatile chip-based nanoscopy becomes ready for histopathology assessment
《Light(Science & Applications)》2022年第5期730-732,共3页Martin Lopez-Garcia 
Nanoscopy is a mature technology used routinely in life science to obtain images well below the optical diffraction limit.But the use of nanoscopy in histopathology assessment is very limited mostly due to the low thr...
关键词：NANOS offering illumination 
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